288 research outputs found
Implementació paral·lela en MPI de l'algorisme de Shanks
L'objectiu d'aquest projecte es implementar la versiĂł en paral·lel de l'algorisme de Shanks en l'entorn MPI. L'algorisme de Shanks resol el problema del logaritme discret, problema en el qual basa la seva seguretat la xifra de clau pĂșblica ElGamal
Cascade Dehydrogenative Hydroboration for the Synthesis of Azaborabenzofulvenes
Tandem dehydrogenative
hydroboration has been established to be
highly effective in the synthesis of BN isosteres of benzofulvene
and derivatives. The scope of this synthetic method is applicable
to a variety of substrates. Spectroscopic and computational studies
indicate that the new azaborabenzofulvenes have similar electronic
properties as their carbonaceous analogues
Attachment and Release of Water Fleasâ Ephippia on a Medium-Sized Waterfowlâs Leg for Migration
Planktonic crustaceans of the genus Daphnia live
in aquatic environments. Although they lack walking and flying capabilities,
they have developed adaptations that facilitate the dispersal of their
dormant forms, ephippia, to cross terrestrial barriers and reach neighborhood
water bodies. It increases the survival rate of their species. It
is reported that one of the ways this spread occurs is the transport
of their ephippia through waterfowlsâ legs. Yet, little is
known about how these ephippia are initially attached to the waterfowlsâ
legs. In this work, using the legs of American Pekin ducks as test
samples, we found that a âcoatingâ mechanism might play
a significant role in this attachment and that surface tension-induced
attraction might have a secondary effect on it. Furthermore, we demonstrated
that, no matter whether a duckâs leg was inserted into water
at a high or low speed, an ephippium could be released from the leg
Attachment and Release of Water Fleasâ Ephippia on a Medium-Sized Waterfowlâs Leg for Migration
Planktonic crustaceans of the genus Daphnia live
in aquatic environments. Although they lack walking and flying capabilities,
they have developed adaptations that facilitate the dispersal of their
dormant forms, ephippia, to cross terrestrial barriers and reach neighborhood
water bodies. It increases the survival rate of their species. It
is reported that one of the ways this spread occurs is the transport
of their ephippia through waterfowlsâ legs. Yet, little is
known about how these ephippia are initially attached to the waterfowlsâ
legs. In this work, using the legs of American Pekin ducks as test
samples, we found that a âcoatingâ mechanism might play
a significant role in this attachment and that surface tension-induced
attraction might have a secondary effect on it. Furthermore, we demonstrated
that, no matter whether a duckâs leg was inserted into water
at a high or low speed, an ephippium could be released from the leg
Screening and unveiling antibacterial mechanism of dandelion phenolic extracts against <i>Staphylococcus aureus</i> by inhibiting intracellular Na<sup>+</sup>âK<sup>+</sup> ATPase based on molecular docking and molecular dynamics simulation
Staphylococcus aureus is one of the most frequently food-contaminated incidence of healthcare-associated Gram-positive bacteria. The antibacterial function and mechanism of phenolic compounds from dandelion are still unclear. Herein, this work aims to screen one of dandelion phenolic extracts with the strongest antibacterial function from its organ such as flower, stem, leaf and root, and to reveal its antibacterial mechanism. The results indicated dandelion flower phenolic extract (DFPE) containing the highest content of caffeic acid, followed by luteolin and luteolin-7-O-glucoside. They, especially caffeic acid and luteolin-7-O-glucoside, played a key role in making the bacterial cellular-membrane ruptured against the bacteria. The leakage of the intracellular substances (adenosine triphosphate and Na+âK+ ATPase) was further confirmed. Conventional hydrogen bond, pi-anion, pi-alkyl were involved in the interaction between caffeic acid or luteolin-7-O-glucoside and Na+âK+ ATPase. Additionally, the dynamic equilibrium of the liganded ATPase complex were achieved after 105âns, and the lower values from the radius of gyration and solvent accessible surface area in the complex demonstrated the highly tight and compact structure of the liganded protein. The highest free binding energy (ÎGbind = â47.80âkJ/mol) between Na+âK+ ATPase and luteolin-7-O-glycloside was observed. Overall, DFPE can be used as an effective anti-bacterial agent due to the contribution of its bioactive ingredients such as caffeic acid and luteolin-7-O-glucoside for membrane-breaking. Communicated by Ramaswamy H. Sarma</p
Chemoselective Synthesis of Polycyclic Spiroindolines and Polysubstituted Pyrroles via the Domino Reaction of 2âIsocyanoethylindoles
Chemoselective
2-isocyanoethylindole-based domino reactions for
the construction of polycyclic spiroindoline derivatives and polysubstituted
pyrroles have been developed. The reaction of 2-isocyanoethylindoles
and <i>gem</i>-diactivated olefins lead to the polycyclic
spiroindoline derivatives (up to 92% yields) in EtOH under reflux
conditions. Furthermore, the three-component reaction of 2-isocyanoethylindoles
with <i>gem</i>-diactivated olefins and secondary amines
afford polysubstituted pyrroles (in moderate yields) in CH<sub>3</sub>CN under reflux conditions
Attachment and Release of Water Fleasâ Ephippia on a Medium-Sized Waterfowlâs Leg for Migration
Planktonic crustaceans of the genus Daphnia live
in aquatic environments. Although they lack walking and flying capabilities,
they have developed adaptations that facilitate the dispersal of their
dormant forms, ephippia, to cross terrestrial barriers and reach neighborhood
water bodies. It increases the survival rate of their species. It
is reported that one of the ways this spread occurs is the transport
of their ephippia through waterfowlsâ legs. Yet, little is
known about how these ephippia are initially attached to the waterfowlsâ
legs. In this work, using the legs of American Pekin ducks as test
samples, we found that a âcoatingâ mechanism might play
a significant role in this attachment and that surface tension-induced
attraction might have a secondary effect on it. Furthermore, we demonstrated
that, no matter whether a duckâs leg was inserted into water
at a high or low speed, an ephippium could be released from the leg
Visualization 1: High-resolution light field reconstruction using a hybrid imaging system
Video corresponds to the high-resolution reconstructed light fields in
Fig. 9(a). Originally published in Applied Optics on 01 April 2016 (ao-55-10-2580
Visualization 2: High-resolution light field reconstruction using a hybrid imaging system
Video corresponds to the high-resolution reconstructed light fields in
Fig. 9(b). Originally published in Applied Optics on 01 April 2016 (ao-55-10-2580
Datasheet1_Comparison of revascularization with conservative medical treatment in maintenance dialysis patient with coronary artery disease: a systemic review and meta-analysis.docx
BackgroundThe primary cause of death among maintenance dialysis patients is coronary artery disease (CAD). However, the best treatment plan has not yet been identified.MethodsThe relevant articles were retrieved from various online databases and references from their inception to October 12, 2022. The studies that compared revascularization [percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)] with medical treatment (MT) among maintenance dialysis patients with CAD were selected. The outcomes evaluated were long-term (with a follow-up of at least 1 year) all-cause mortality, long-term cardiac mortality, and the incidence rate of bleeding events. Bleeding events are defined according to TIMI hemorrhage criteria: (1) major hemorrhage, intracranial hemorrhage or clinically visible hemorrhage (including imaging diagnosis) with decrease of hemoglobin concentration â„5â
g/dl; (2) minor hemorrhage, clinically visible bleeding (including imaging diagnosis) with a drop in hemoglobin of 3â5â
g/dl; (3) minimal hemorrhage, clinically visible bleeding with hemoglobin drop ResultsA total of eight studies with 1,685 patients were selected for this meta-analysis. The current findings suggested that revascularization was associated with low long-term all-cause mortality and long-term cardiac mortality but a similar incidence rate of bleeding events compared to MT. However, subgroup analyses indicated that PCI is linked to decreased long-term all-cause mortality compared to MT but CABG did not significantly differ from MT in terms of long-term all-cause mortality. Revascularization also showed lower long-term all-cause mortality compared to MT among patients with stable CAD, single-vessel disease, and multivessel disease but did not reduce long-term all-cause mortality among patients with ACS.ConclusionLong-term all-cause mortality and long-term cardiac mortality were reduced by revascularization in comparison to MT alone in patients undergoing dialysis. Larger randomized studies are needed to confirm the conclusion of this meta-analysis.</p
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