34 research outputs found
The architecture of a web service-based remote control service system
There is increasing attention recently in the development of
remote control and monitoring. Many applications and
experiments have been done to apply internet technology in this
field with the aim of developing a general and expendable
architecture. In this paper, a novel Web Service-based Remote
Control Service System (WSRCSS) is proposed. Compared with
other designs, this system focuses on offering a service
development and delivery environment. The system architecture
and data structure for the system are given. Related works are also
discussed in this paper
The architecture of a web service-based remote control service system
There is increasing attention recently in the development of
remote control and monitoring. Many applications and
experiments have been done to apply internet technology in this
field with the aim of developing a general and expendable
architecture. In this paper, a novel Web Service-based Remote
Control Service System (WSRCSS) is proposed. Compared with
other designs, this system focuses on offering a service
development and delivery environment. The system architecture
and data structure for the system are given. Related works are also
discussed in this paper
Regio- and Chemoselective Diboration of Allenes with Unsymmetrical Diboron: Formation of Vinyl and Allyl Boronic Acid Derivatives
A platinum-catalyzed
terminal diboration of 1,1-disubstituted allenes
using a differentially protected diboron is described. Diboration
occurs in a regio- and chemoselective fashion to furnish vinyl and
allyl boronates in good to excellent yield and selectivity. Transformation
of the bis-boronyl products to other functional groups as well as
in chemoselective cross-coupling is demonstrated
Plasmon-Induced Photoreaction of <i>o</i>‑Nitrobenzyl-Based Ligands under 550 nm Light
We
have studied the plasmon-driven photoreaction of a dual thiol-anchored <i>o</i>-nitrobenzyl-based photouncaging ligand on silver nanoparticles.
Previous results have shown that this compound strongly anchors to
gold surfaces, and a 1 J/cm<sup>2</sup> dose of UV light induces the
intended photoreaction, uncaging an amine on the surface. This allows
for photopatterning and the selective adhesion of gold nanospheres
(AuNSs) to a surface via electrostatic attraction between the positively
charged amines and negatively charged AuNSs. Here, we report that
when the ligand is adsorbed on a silver nanospheroid film (AgNS),
an additional photoreaction induced by green light inhibits AuNSs
adhesion in the UV exposed film. Our findings suggest that this is
a result of the neutralization of the amine group’s ability
to become charged, as opposed to the removal of the ligand from the
surface of the silver nanospheroids. We hypothesize that this neutralization
may be due to a form of hot-hole-induced photocatalysis, resulting
in an Nî—»N double bond between two neighboring ligands. This
reaction has been documented in similarly amine-terminated moieties.
This neutralization allows for a more fine-tuned, plasmonically based
control of the ligand’s photoreaction, as the green light exposure
only affects the ligand if it has previously been cleaved by UV light,
and makes it possible to perform reverse photopatterning on the surface
Flow chart of selection process for the eligible studies.
<p>Flow chart of selection process for the eligible studies.</p
The prognostic value of <i>KRAS</i> mutation by cell-free DNA in cancer patients: A systematic review and meta-analysis
<div><p><i>KRAS</i> mutation has been found in various types of cancer. However, the prognostic value of <i>KRAS</i> mutation in cell-free DNA (cfDNA) in cancer patients was conflicting. In the present study, a meta-analysis was conducted to clarify its prognostic significance. Literature searches of Cochrane Library, EMBASE, PubMed and Web of Science were performed to identify studies related to <i>KRAS</i> mutation detected by cfDNA and survival in cancer patients. Two evaluators reviewed and extracted the information independently. Review Manager 5.3 software was used to perform the statistical analysis. Thirty studies were included in the present meta-analysis. Our analysis showed that <i>KRAS</i> mutation in cfDNA was associated with a poorer survival in cancer patients for overall survival (OS, HR 2.02, 95% CI 1.63–2.51, <i>P</i><0.01) and progression-free survival (PFS, HR 1.64, 95% CI 1.27–2.13, <i>P</i><0.01). In subgroup analyses, <i>KRAS</i> mutation in pancreatic cancer, colorectal cancer, non-small cell lung cancer and ovarian epithelial cancer had HRs of 2.81 (95% CI 1.83–4.30, <i>P</i><0.01), 1.67 (95% CI 1.25–2.42, <i>P</i><0.01), 1.64 (95% CI 1.13–2.39, <i>P</i> = 0.01) and 2.17 (95% 1.12–4.21, <i>p</i> = 0.02) for OS, respectively. In addition, the ethnicity didn’t influence the prognostic value of <i>KRAS</i> mutation in cfDNA in cancer patients (<i>p</i> = 0.39). Prognostic value of KRAS mutation was slightly higher in plasma than in serum (HR 2.13 vs 1.65), but no difference was observed (<i>p</i> = 0.37). Briefly, <i>KRAS</i> mutation in cfDNA was a survival prognostic biomarker in cancer patients. Its prognostic value was different in various types of cancer.</p></div
Survival curves of the number of resected lymph nodes (nLNs).
<p>(A) Overall survival curves of nLNs (<i>p</i><0.001). (B) Disease free survival curves of nLNs (<i>p</i> = 0.004).</p
Survival curves of the number of resected lymph nodes (nLNs) in patients with stage I.
<p>(A) 1 resected LN as cutoff (<i>p</i> = 0.001). (B) 3 resected LNs as cutoff (<i>p</i> = 0.007). (C) 5 resected LNs as cutoff (<i>p></i>0.05). (D) 7 resected LNs as cutoff (<i>p></i>0.05).</p
The sensitivity analysis for the meta-analysis.
<p>The sensitivity analysis for the meta-analysis.</p
Survival curves of the new predictor (nLNs combined with tumor size).
<p>(A) Overall survival curves of the new predictor (<i>p</i><0.001). (B) Disease free survival curves of the new predictor (<i>p</i><0.001).</p