413 research outputs found

    Of transgender and sin in Asia

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    There are vibrant transgender communities in both Thailand and the Philippines (e.g. see Winter, 2006; Winter, Sasot and King, in prep). Yet the languages of Thailand and the Philippines lack single words that correspond to our words ‘transgender’/ ‘transsexual’. In Thailand the commonest word for transwomen is kathoey. Originally used to describe hermaphrodites, the word later broadened to embrace any male contravening gender role expectations (gays, effeminate males etc), only recently (with the word ‘gay’ entrenched in Thai) used more specifically to describe transwomen. The word kathoey can carry negative connotations; transwomen are not always comfortable with it. One reason may be that the word implies that one is a variant of male rather than female. Whether it is taken offensively depends a lot on how it is used. In this paper I use the word respectfully, seeking to reclaim it in the way that Western gays have done with the word ‘queer’AsiaPacifiQueer Network, Australian National Universit

    Energy and Environmental Policy Trends: The Growing Opportunity for LNG in China

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    THE GROWING OPPORTUNITY FOR LNG IN CHINANatural gas consumption in China has been growing rapidly since 2006 and was 237 billion cubic metres in 2017. Domestic natural gas production has not kept pace, leaving substantial opportunity for LNG importers.In 2016 the Chinese National Development and Reform Commission released the 13th Five-Year Plan for the Natural Gas Industry, which set a goal of natural gas accounting for 10% of total primary energy consumption by 2020. China’s total energy consumption in 2016 was equivalent to 3,053 million barrels of oil; natural gas accounted for 189.3 million barrels of oil equivalent, 6.2% of total energy consumption

    The Child Play Behavior and Activity Questionnaire: A Parent-Report Measure of Childhood Gender-Related Behavior in China

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    Boys and girls establish relatively stable gender stereotyped behavior patterns by middle childhood. Parent-report questionnaires measuring children’s gender-related behavior enable researchers to conduct large-scale screenings of community samples of children. For school-aged children, two parent-report instruments, the Child Game Participation Questionnaire (CGPQ) and the Child Behavior and Attitude Questionnaire (CBAQ), have long been used for measuring children’s sex-dimorphic behaviors in Western societies, but few studies have been conducted using these measures for Chinese populations. The current study aimed to empirically examine and modify the two instruments for their applications to Chinese society. Parents of 486 Chinese boys and 417 Chinese girls (6–12 years old) completed a questionnaire comprising items from the CGPQ and CBAQ, and an additional 14 items specifically related to Chinese gender-specific games. Items revealing gender differences in a Chinese sample were identified and used to construct a Child Play Behavior and Activity Questionnaire (CPBAQ). Four new scales were generated through factor analysis: a Gender Scale, a Girl Typicality Scale, a Boy Typicality Scale, and a Cross-Gender Scale (CGS). These scales had satisfactory internal reliabilities and large effect sizes for gender. The CPBAQ is believed to be a promising instrument for measuring children’s gender-related behavior in China

    Prevalence and correlates of sexual behaviors among university students: a study in Hefei, China

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    In China, sexual health and behaviors of young people have become a growing public concern but few studies have been conducted to investigate the prevalence and psychosocial correlates of the phenomenon. A self-reported questionnaire survey on youth sexual behaviors was conducted among 1,500 university students in 2011 at Hefei, a middle-size city in eastern China. A total of 1,403 students (age = 20.30 Âą 1.27 years) completed the questionnaire with a high response rate of 93.5%. Among the respondents, 12.6% (15.4% of male versus 8.6% of female) students reported having pre-marital heterosexual intercourse; 10.8% (10.5% of males versus 11.2% females) had oral sex; 2.7% (3.4% of males versus 1.7% females) reported same-sex activities; 46% (70.3% of males versus 10.8% of females) reported masturbation behaviors; 57.4% (86.2% of males versus 15.6% females) students viewed pornography. In terms of sexual communication about sexual knowledge acquisition, 13.7% (10.7% of males versus 18% of females) talked to their parents about sex; 7.1% (6.1% of males versus 8.4% of females) students reported having conversation with parents on contraception. About forcing sexual behavior, 2.7% (4% of males versus 0.9% of females) reported forcing their sexual partners to have sex, and 1.9% (2.4% of males versus 1.2% of females) reported being forced to have sex. Gender was found to be significant predictor of sexual behaviors in university students: males reported more sexual behaviors including sexual fantasy, heterosexual intercourse, masturbation, viewing pornography and talking about sex with friends. Several correlates of sexual behaviors were identified for students of different gender separately. For males, having romantic relationships, past sex education experiences, low educational aspirations, time spent on the Internet, and urban native settings were significantly associated with more sexual behaviors. For female students, having romantic relationships and urban native settings predicted sexual behaviors. Sexual behavior among University students in China is not uncommon, although there are limited ways for students to acquire sex-related knowledge: male students showed significantly more sexual behaviors than female students. Having romantic relationships and more time spent online were important predictors of sexual behaviors among university students. To guide healthy sexual behaviors in young people, comprehensive sex education programs that provide necessary sexual health knowledge about safe sex should be developed and implemented in universities in China, particularly for students who have romantic relationships and those who spend long periods of time on the Internet

    Weak weak approximation and the Hilbert property for degree-two del Pezzo surfaces

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    We prove that del Pezzo surfaces of degree 22 over a field kk satisfy weak weak approximation if kk is a number field and the Hilbert property if kk is Hilbertian of characteristic zero, provided that they contain a kk-rational point lying neither on any 44 of the 5656 exceptional curves nor on the ramification divisor of the anticanonical morphism. This builds upon results of Manin, Salgado--Testa--V\'arilly-Alvarado, and Festi--van Luijk on the unirationality of such surfaces, and upon work of the first two authors verifying weak weak approximation under the assumption of a conic fibration.Comment: 22 pages, minor edits, comments welcom

    Modelling changes in the pharmacokinetics of tacrolimus during pregnancy after kidney transplantation:A retrospective cohort study

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    Aims: Pregnancy after kidney transplantation is realistic but immunosuppressants should be continued to prevent rejection. Tacrolimus is safe during pregnancy and is routinely dosed based on whole-blood predose concentrations. However, maintaining these concentrations is complicated as physiological changes during pregnancy affect tacrolimus pharmacokinetics. The aim of this study was to describe tacrolimus pharmacokinetics throughout pregnancy and explain the changes by investigating covariates in a population pharmacokinetic model. Methods: Data of pregnant women using a twice-daily tacrolimus formulation following kidney transplantation were retrospectively collected from 6 months before conception, throughout gestation and up to 6 months postpartum. Pharmacokinetic analysis was performed using nonlinear mixed effects modelling. Demographic, clinical and genetic parameters were evaluated as covariates. The final model was evaluated using goodness-of-fit plots, visual predictive checks and a bootstrap analysis. Results: A total of 260 whole-blood tacrolimus predose concentrations from 14 pregnant kidney transplant recipients were included. Clearance increased during pregnancy from 34.5 to 41.7 L/h, by 15, 19 and 21% in the first, second and third trimester, respectively, compared to prior to pregnancy. This indicates a required increase in the tacrolimus dose by the same percentage to maintain the prepregnancy concentration. Haematocrit and gestational age were negatively correlated with tacrolimus clearance (P ≤ 0.01), explaining 18% of interindividual and 85% of interoccasion variability in oral clearance.Conclusions: Tacrolimus clearance increases during pregnancy, resulting in decreased exposure to tacrolimus, which is explained by gestational age and haematocrit. To maintain prepregnancy target whole-blood tacrolimus predose concentrations during pregnancy, increasing the dose is required.</p

    The Grizzly, September 15, 1989

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    Greek Golden Age Growing Dark • U.C. Slasher Case Finally Closed • Letters: Physics Major Majorly Miffed; Wismer Eggs on Disgusted Diner • SAO Makes Room for Zimmer • Go Abroad: It\u27s Worth It • Mann\u27s Soda Can Hit with Crowd • Bears Upset Hoyas in Season Opener • Grizzlies Take Tourney with Defense • V-ball: Victors! • Endurance is Key • Athletes of the Week • Pledging: Git! • Myrin Booking • Lucas Heads Frosh Seminar • Dumas: Cook of Monte Cristo • Smith Donation • Freshmen Make Necessary Adjustmentshttps://digitalcommons.ursinus.edu/grizzlynews/1240/thumbnail.jp

    Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study

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    Background Osteosarcoma is an aggressive and painful bone neoplasm in dogs. Previous studies have reported epidemiological associations suggesting that large body mass, long bone length and the genetics of certain breeds including the Rottweiler are associated with elevated osteosarcoma risk. However, these studies were often limited by selection bias and confounding factors, and have rarely offered insights into breed-associated protection for osteosarcoma. The current study includes 1756 appendicular and axial osteosarcoma cases presenting to VPG Histology (Bristol, UK) compared against a control population of 905,211 dogs without osteosarcoma from primary care electronic patient records in the VetCompass™ dataset. Methods and study design Retrospective, case-control study. Multivariable logistic regression analysis explored associations between demographic risk factors (including breed, chondrodystrophy, age, sex/neuter status, skull-shape, and body mass) and osteosarcoma of all anatomical sites. Results We identified several breeds with increased and reduced odds of osteosarcoma. At highest risk were the Rottweiler and Great Dane, with > 10 times the odds of osteosarcoma compared with crossbreds, and the Rhodesian Ridgeback, which has not featured in previous lists of at-risk breeds for osteosarcoma, and had an odds ratio of 11.31 (95% confidence interval 7.37–17.35). Breeds at lowest risk of osteosarcoma (protected breeds) included the Bichon Frise, the French Bulldog and the Cavalier King Charles Spaniel, all with odd ratios of less than 0.30 compared with crossbreds. Body mass was strongly associated with osteosarcoma risk; dogs over 40 kg exhibited osteosarcoma odds of 45.44 (95% confidence interval 33.74–61.20) compared with dogs less than 10 kg. Chondrodystrophic breeds had an osteosarcoma odds ratio of 0.13 (95% confidence interval 0.11–0.16) compared with non-chondrodystrophic breeds. Conclusions This study provides evidence of strong breed-associated osteosarcoma risk and protection, suggesting a genetic basis for osteosarcoma pathogenesis. It highlights that breeds selected for long legs/large body mass are generally overrepresented amongst at-risk breeds, whilst those selected for short leg length/small body mass are generally protected. These findings could inform genetic studies to identify osteosarcoma risk alleles in canines and humans; as well as increasing awareness amongst veterinarians and owners, resulting in improved breeding practices and clinical management of osteosarcoma in dogs

    Planning, implementation, and monitoring Pacific salmonid recovery following the removal of two hydroelectric dams on Washington\u27s Elwha River

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    The removal of Elwha and Glines Canyon dams on the Elwha River is the largest existing dam removal project in the United States. Project planning, implementation, and monitoring have occurred over 30 years and has required diverse technical expertise. Because of the size and nature of the project—two high-head dams releasing massive amounts of sediment into the river, estuary, and nearshore ecosystem—the project was unprecedented and required a great deal of technical expertise to plan, execute, and monitor. The relative success of this project required effective collaboration among individuals and organizations with varying missions. Individuals with diverse technical expertise (i.e., engineering, geomorphology, hydrology, botany, wildlife, fisheries, stream ecology, ecological monitoring) have successfully collaborated to develop several technical plans ensuring dam removal was completed, while at the same time protecting a city water supply, infrastructure, and listed and unlisted salmonids in the basin. This collaboration has continued following dam removal through the implementation of a monitoring and adaptive management plan. Our monitoring strategy often uses multiple scientific methods to evaluate metrics or performance indicators to create multiple lines of evidence, reduce uncertainty, and ensure data availability. Employing such diverse methods would not have been possible without multidisciplinary and multiagency collaboration. Collaboration and extensive monitoring has allowed project partners to identify potential barriers, assess the rate and extent of recolonization, estimate abundance, life history attributes, and productivity. This collaborative multidisciplinary approach has allowed us to monitor salmonid recovery, while also improving our understanding of ecosystem response and linkages. This has resulted in the Elwha River being one of the best studied dam removal projects in history
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