99 research outputs found
sj-xlsx-2-dhj-10.1177_20552076231169846 - Supplemental material for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety
Supplemental material, sj-xlsx-2-dhj-10.1177_20552076231169846 for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety by Wenjun Wang, Tianlong Liu and Yi Zhang in DIGITAL HEALTH</p
sj-xlsx-3-dhj-10.1177_20552076231169846 - Supplemental material for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety
Supplemental material, sj-xlsx-3-dhj-10.1177_20552076231169846 for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety by Wenjun Wang, Tianlong Liu and Yi Zhang in DIGITAL HEALTH</p
sj-png-1-dhj-10.1177_20552076231169846 - Supplemental material for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety
Supplemental material, sj-png-1-dhj-10.1177_20552076231169846 for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety by Wenjun Wang, Tianlong Liu and Yi Zhang in DIGITAL HEALTH</p
sj-xlsx-5-dhj-10.1177_20552076231169846 - Supplemental material for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety
Supplemental material, sj-xlsx-5-dhj-10.1177_20552076231169846 for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety by Wenjun Wang, Tianlong Liu and Yi Zhang in DIGITAL HEALTH</p
sj-xlsx-4-dhj-10.1177_20552076231169846 - Supplemental material for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety
Supplemental material, sj-xlsx-4-dhj-10.1177_20552076231169846 for An integrated targeted metabolomics and network pharmacology approach to exploring the mechanism of ellagic acid against sleep deprivation-induced memory impairment and anxiety by Wenjun Wang, Tianlong Liu and Yi Zhang in DIGITAL HEALTH</p
Image3_The oncogenic role of SNRPB in human tumors: A pan-cancer analysis.TIF
Purpose: The purpose of this study was to explore the oncogenic role of small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB) in human tumors.Materials and methods: Study cases were acquired from The Cancer Genome Atlas database, the Gene Expression Omnibus database, The Human Protein Atlas, and the Clinical Proteomic Tumor Analysis Consortium. We then used the R package and several online tools to analyze and visualize the role of SNRPB across tumors.Results: We found that the expression of SNRPB was significantly increased in 28 of 33 tumors, and higher expression was observed in late pathological and TNM stages. Significantly decreased levels of SNRPB promoter methylation were observed in 12 tumors. SNRPB was found to be a risk factor for decreased overall survival in 10 tumors (p Conclusion and limitations: The expression of SNRPB was significantly elevated in almost all tumors, and the decreased promoter methylation level may contribute to the elevated expression of SNRPB. SNRPB may facilitate the progression of pathological and TNM stages and is a risk factor for unfavorable prognosis across tumors. However, our research was based on data obtained from public databases, without further validation of our findings at the cellular and animal levels. Therefore, further studies are needed to clarify the oncogenic mechanism of SNRPB and its potential as a therapeutic target.</p
Image1_The oncogenic role of SNRPB in human tumors: A pan-cancer analysis.JPEG
Purpose: The purpose of this study was to explore the oncogenic role of small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB) in human tumors.Materials and methods: Study cases were acquired from The Cancer Genome Atlas database, the Gene Expression Omnibus database, The Human Protein Atlas, and the Clinical Proteomic Tumor Analysis Consortium. We then used the R package and several online tools to analyze and visualize the role of SNRPB across tumors.Results: We found that the expression of SNRPB was significantly increased in 28 of 33 tumors, and higher expression was observed in late pathological and TNM stages. Significantly decreased levels of SNRPB promoter methylation were observed in 12 tumors. SNRPB was found to be a risk factor for decreased overall survival in 10 tumors (p Conclusion and limitations: The expression of SNRPB was significantly elevated in almost all tumors, and the decreased promoter methylation level may contribute to the elevated expression of SNRPB. SNRPB may facilitate the progression of pathological and TNM stages and is a risk factor for unfavorable prognosis across tumors. However, our research was based on data obtained from public databases, without further validation of our findings at the cellular and animal levels. Therefore, further studies are needed to clarify the oncogenic mechanism of SNRPB and its potential as a therapeutic target.</p
Image2_The oncogenic role of SNRPB in human tumors: A pan-cancer analysis.TIF
Purpose: The purpose of this study was to explore the oncogenic role of small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB) in human tumors.Materials and methods: Study cases were acquired from The Cancer Genome Atlas database, the Gene Expression Omnibus database, The Human Protein Atlas, and the Clinical Proteomic Tumor Analysis Consortium. We then used the R package and several online tools to analyze and visualize the role of SNRPB across tumors.Results: We found that the expression of SNRPB was significantly increased in 28 of 33 tumors, and higher expression was observed in late pathological and TNM stages. Significantly decreased levels of SNRPB promoter methylation were observed in 12 tumors. SNRPB was found to be a risk factor for decreased overall survival in 10 tumors (p Conclusion and limitations: The expression of SNRPB was significantly elevated in almost all tumors, and the decreased promoter methylation level may contribute to the elevated expression of SNRPB. SNRPB may facilitate the progression of pathological and TNM stages and is a risk factor for unfavorable prognosis across tumors. However, our research was based on data obtained from public databases, without further validation of our findings at the cellular and animal levels. Therefore, further studies are needed to clarify the oncogenic mechanism of SNRPB and its potential as a therapeutic target.</p
Nanospot Soldering Polystyrene Nanoparticles with an Optical Fiber Probe Laser Irradiating a Metallic AFM Probe Based on the Near-Field Enhancement Effect
With the development of nanoscience
and nanotechnology for the
bottom-up nanofabrication of nanostructures formed from polystyrene
nanoparticles, joining technology is an essential step in the manufacturing
and assembly of nanodevices and nanostructures in order to provide
mechanical integration and connection. To study the nanospot welding
of polystyrene nanoparticles, we propose a new nanospot-soldering
method using the near-field enhancement effect of a metallic atomic
force microscope (AFM) probe tip that is irradiated by an optical
fiber probe laser. On the basis of our theoretical analysis of the
near-field enhancement effect, we set up an experimental system for
nanospot soldering; this approach is carried out by using an optical
fiber probe laser to irradiate the AFM probe tip to sinter the nanoparticles,
providing a promising technical approach for the application of nanosoldering
in nanoscience and nanotechnology
Degrees of enzymolysis of PSGs at 2, 6, 10, and 20 DAA.
<p>Degrees of enzymolysis of PSGs at 2, 6, 10, and 20 DAA.</p
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