Integrated Water Law: Local to International

Table of Contents INTRODUCTION PART I: WATER ALLOCATION: LOCAL AND INTERNATIONAL CHAPTER 1: LOCAL WATER LAW CHAPTER TWO: INTERNATIONAL WATER LAW COMPARISON OF RESTATEMENT AND INTERNATIONAL FACTORS FOR REASONABLE USE CHAPTER 3: THE VERMEJO RIVER CHAPTER 4 WATER LAWS: ENTITLEMENTS, RIGHTS, DUTIES AND PRIVILEGES CONCLUSION TO PART I PART II: NEGOTIATING WATERCOURSE ENTITLEMENTS CHAPTER FIVE: WATERCOURSE NEGOTIATIONS ARE DIFFERENT CHAPTER SIX: THE ROLE OF LA

The Rio Grande as an International River

The Rio Grande is divided into two major river reaches and has different legal regimes for each. New Mexico is primarily concerned with the Rio Grande from the headwaters in Colorado to Ft. Quitman in Texas, a distance of approximately 670 miles. This section of the river is the subject of the1906 Rio Grande Convention (Treaty) between the United States and Mexico. The lower section of the Rio Grande from Ft. Quitman to the Gulf of Mexico is the subject of the 1944 Rivers Treaty between the United States and Mexico; the 1944 Rivers Treaty also includes the Colorado and Tijuana River. As with many international and interstate rivers, the Rio Grande’s history, particularly that leading up to the 1906 Rio Grande Convention, helps explain the law of the river t

Integrated Water Law: Local to International

Table of Contents INTRODUCTION PART I: WATER ALLOCATION: LOCAL AND INTERNATIONAL CHAPTER 1: LOCAL WATER LAW CHAPTER TWO: INTERNATIONAL WATER LAW COMPARISON OF RESTATEMENT AND INTERNATIONAL FACTORS FOR REASONABLE USE CHAPTER 3: THE VERMEJO RIVER CHAPTER 4 WATER LAWS: ENTITLEMENTS, RIGHTS, DUTIES AND PRIVILEGES CONCLUSION TO PART I PART II: NEGOTIATING WATERCOURSE ENTITLEMENTS CHAPTER FIVE: WATERCOURSE NEGOTIATIONS ARE DIFFERENT CHAPTER SIX: THE ROLE OF LA

Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies

To study the substrate specificity of enzymes, we use the amidohydrolase and enolase superfamilies as model systems; members of these superfamilies share a common TIM barrel fold and catalyze a wide range of chemical reactions. Here, we describe a collaboration between the Enzyme Specificity Consortium (ENSPEC) and the New York SGX Research Center for Structural Genomics (NYSGXRC) that aims to maximize the structural coverage of the amidohydrolase and enolase superfamilies. Using sequence- and structure-based protein comparisons, we first selected 535 target proteins from a variety of genomes for high-throughput structure determination by X-ray crystallography; 63 of these targets were not previously annotated as superfamily members. To date, 20 unique amidohydrolase and 41 unique enolase structures have been determined, increasing the fraction of sequences in the two superfamilies that can be modeled based on at least 30% sequence identity from 45% to 73%. We present case studies of proteins related to uronate isomerase (an amidohydrolase superfamily member) and mandelate racemase (an enolase superfamily member), to illustrate how this structure-focused approach can be used to generate hypotheses about sequence–structure–function relationships