Unscarred uterine rupture: a retrospective analysis in tertiary center

Background: Uterine rupture is a catastrophic obstetrical emergency associated with a significant fetomaternal morbidity and mortality. Many risk factors for uterine rupture, as well as a wide range of clinical presentations have been identified. The objectives of the present study were to analyze the frequency, predisposing factors, maternal and fetal outcomes of unscarred uterine rupture.Methods: A retrospective analysis of cases of unscarred uterine rupture was conducted at the Department of Obstetrics and Gynaecology Jhalawar medical college Jhalawar Rajasthan from January 2009 to December 2016.Results: Our analysis comprised of 11 cases with unscarred uterine rupture. Incidence of unscarred uterine rupture is 0.01% or 1/10,000  deliveries.Conclusions: In our study there was no history of uterine scarring so the main predisposing factor are maltiparity and obstructed labour. The grand multiparas women and obstructed labour must be managed by proper trained personnel and in tertiary care center in order to avoid the morbidity and mortality

Bank Recapitalisation and Credit Growth: The Indian Case

The continuing deterioration in asset quality of public sector banks in India since 2012 has had multidimensional ramifications. On the one hand, while significant loan loss provisions were required to be kept, eroding the profitability of these banks, on the other hand, it affected their risk-taking ability and resources available for on-lending to commercial sector. From a macroeconomic perspective thus, poor asset quality and lower economic growth reinforced each other into a vicious cycle. The government intermittently infused capital in the public-sector banks, but most of that was absorbed by the continuing deterioration in asset quality, delaying the revival in the credit growth cycle. This led to the question of how much capital infusion is necessary to kick-start the credit cycle. Using bank-wise data for the period 2008-18, the present study analyses this question in a dynamic panel framework. The findings of the study suggest that the relationship between bank capital and credit growth is non-linear. Any amount of recapitalisation in banks is may be helpful in accelerating credit growth. However, the study found the single threshold level 13.1 per cent of CRAR level would be optimal. Above this threshold level, incremental increase in bank capital has positive but declining marginal effects on lending

Bank Recapitalisation and Credit Growth: The Indian Case

The continuing deterioration in asset quality of public sector banks in India since 2012 has had multidimensional ramifications. On the one hand, while significant loan loss provisions were required to be kept, eroding the profitability of these banks, on the other hand, it affected their risk-taking ability and resources available for on-lending to commercial sector. From a macroeconomic perspective thus, poor asset quality and lower economic growth reinforced each other into a vicious cycle. The government intermittently infused capital in the public-sector banks, but most of that was absorbed by the continuing deterioration in asset quality, delaying the revival in the credit growth cycle. This led to the question of how much capital infusion is necessary to kick-start the credit cycle. Using bank-wise data for the period 2008-18, the present study analyses this question in a dynamic panel framework. The findings of the study suggest that the relationship between bank capital and credit growth is non-linear. Any amount of recapitalisation in banks is may be helpful in accelerating credit growth. However, the study found the single threshold level 13.1 per cent of CRAR level would be optimal. Above this threshold level, incremental increase in bank capital has positive but declining marginal effects on lending

State of fabric producing units in India

The estimates in the government funded survey of handloom and powerloom sectors of the number of units, looms and employment are not reliable since they are especially designed to identify units eligible for sector-specific schemes. The Unit-wise Annual survey of Industries and the NSSO 62nd round data for 2005-06 cover the entire manufacturing data, but the results derived for variables such as value added, output, fabric production etc are also not considered reliables as the small units have a tendency to under report their production in order to retain the benefits of small-scale sector tax incentives. This paper presents an analysis of the National Counicl of Applied Economic Research sample survey, which was designed to estimate the weighted per unit ratio for various size classess of units belonging to the handloom, powerloom mill and kitting sectors

Unscarred uterine rupture: a retrospective analysis in tertiary center

Background: Uterine rupture is a catastrophic obstetrical emergency associated with a significant fetomaternal morbidity and mortality. Many risk factors for uterine rupture, as well as a wide range of clinical presentations have been identified. The objectives of the present study were to analyze the frequency, predisposing factors, maternal and fetal outcomes of unscarred uterine rupture.Methods: A retrospective analysis of cases of unscarred uterine rupture was conducted at the Department of Obstetrics and Gynaecology Jhalawar medical college Jhalawar Rajasthan from January 2009 to December 2016.Results: Our analysis comprised of 11 cases with unscarred uterine rupture. Incidence of unscarred uterine rupture is 0.01% or 1/10,000  deliveries.Conclusions: In our study there was no history of uterine scarring so the main predisposing factor are maltiparity and obstructed labour. The grand multiparas women and obstructed labour must be managed by proper trained personnel and in tertiary care center in order to avoid the morbidity and mortality

Credit and Efficiency in Indian Agriculture: Evidence from Household-Level Data

The paper estimates technical efficiency in agriculture for cultivator households applying the Data Envelopment technique to the Rural Economic and Demographic Survey (REDS) database covering 17 major States in India, and analyses its association with agricultural credit along with other household-level economic and demographic variables through a Tobit framework. Agricultural efficiency was observed to have a positive and significant relation with agricultural credit. The impact was positive for all cultivator households including marginal and small cultivator households. Agricultural credit influenced efficiency when directly factored into the model but also in an indirect manner when replaced by various variable and fixed inputs generally purchased by a cultivator using crop and investment credit. Most of these inputs showed positive elasticity with respect to agricultural credit. The paper underlines the need to continue with the policy of providing directed credit support to agriculture with a distinct thrust on marginal and small cultivators

Antileukemic Activity of hsa-miR-203a-5p by Limiting Glutathione Metabolism in Imatinib-Resistant K562 Cells

Imatinib has been the first and most successful tyrosine kinase inhibitor (TKI) for chronic myeloid leukemia (CML), but many patients develop resistance to it after a satisfactory response. Glutathione (GSH) metabolism is thought to be one of the factors causing the emergence of imatinib resistance. Since hsa-miR-203a-5p was found to downregulate Bcr-Abl1 oncogene and also a link between this oncogene and GSH metabolism is reported, the present study aimed to investigate whether hsa-miR-203a-5p could overcome imatinib resistance by targeting GSH metabolism in imatinib-resistant CML cells. After the development of imatinib-resistant K562 (IR-K562) cells by gradually exposing K562 (C) cells to increasing doses of imatinib, resistant cells were transfected with hsa-miR-203a-5p (R+203). Thereafter, cell lysates from various K562 cell sets (imatinib-sensitive, imatinib-resistant, and miR-transfected imatinib-resistant K562 cells) were used for GC-MS-based metabolic profiling. L-alanine, 5-oxoproline (also known as pyroglutamic acid), L-glutamic acid, glycine, and phosphoric acid (Pi)—five metabolites from our data, matched with the enumerated 28 metabolites of the MetaboAnalyst 5.0 for the GSH metabolism. All of these metabolites were present in higher concentrations in IR-K562 cells, but intriguingly, they were all reduced in R+203 and equated to imatinib-sensitive K562 cells (C). Concludingly, the identified metabolites associated with GSH metabolism could be used as diagnostic markers