17,483 research outputs found

    Strain specific effects of low level lead exposure on associative learning and memory in rats.

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    Exposure to lead (Pb) remains a significant public health concern. Lead exposure in early life impairs the normal development of numerous cognitive and neurobehavioral processes. Previous work has shown that the effects of developmental Pb exposure on gene expression patterns in the brain are modulated by various factors including the developmental timing of the exposure, level of exposure, sex, and genetic background. Using gene microarray profiling, we previously reported a significant strain-specific effect of Pb exposure on the hippocampal transcriptome, with the greatest number of differentially expressed transcripts in Long Evans (LE) rats and the fewest in Sprague Dawley (SD) rats. The present study examined the extent to which this differential effect of Pb on hippocampal gene expression might influence behavior. Animals (males and females) were tested in a trace fear conditioning paradigm to evaluate effects of Pb exposures (perinatal (PERI; gestation to postnatal day 21) or early postnatal (EPN; postnatal day 1 to day 21)) on associative learning and memory. All animals (Pb-exposed and non-Pb-exposed controls) showed normal acquisition of the conditioned stimulus (tone)-unconditioned stimulus (footshock) association. Long Evans rats showed a significant deficit in short- and long-term recall, influenced by sex and the timing of Pb exposure (PERI or EPN). In contrast, Pb exposure had no significant effect on memory consolidation or recall in any SD rats. These results further demonstrate the important influence of genetic background to the functional outcomes from developmental Pb exposure

    Field theoretic calculation of scalar turbulence

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    The cascade rate of passive scalar and Bachelor's constant in scalar turbulence are calculated using the flux formula. This calculation is done to first order in perturbation series. Batchelor's constant in three dimension is found to be approximately 1.25. In higher dimension, the constant increases as d1/3d^{1/3}.Comment: RevTex4, publ. in Int. J. Mod. Phy. B, v.15, p.3419, 200

    Cellulose based materials to accelerate the transition towards sustainability

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    Several significant sectors use cellulose, including paper manufacturing, cellophane, textiles (including rayon and viscose), and food and medicine additives. It can be utilised as a raw materials in production of fuel sources like cellulosic ethanol. Crystalline cellulose possesses a tensile strength of about 7.5 GPa, Young’s modulus of 110-220 GPa and as the most abundantly available natural polymer, with excellent biocompatibility, good degradation and regeneration properties, it is considered as a remarkable biomaterial. Cellulose-based materials can be fabricated with tuneable magnetic properties, electrical conductivity, photosensitivity, sensing abilities, catalytic activity, and other specific properties by incorporating nanoparticles. These qualities make cellulose a sustainable multifunctional material. To harness such properties, strenuous efforts are being made to manufacture cellulose based materials through a wide number of manufacturing processes. This review provides an overview of the current readiness in producing cellulose-based functional materials by surveying the manufacturing procedures, characteristics and their potential applications for the end users. Future directions and opportunities of work are suggested and the limitations inherent with every process and the challenges that needs to be overcome in scalable manufacturing of cellulose-based materials are also discussed

    Calculation of renormalized viscosity and resistivity in magnetohydrodynamic turbulence

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    A self-consistent renormalization (RG) scheme has been applied to nonhelical magnetohydrodynamic turbulence with normalized cross helicity σc=0\sigma_c =0 and σc1\sigma_c \to 1. Kolmogorov's 5/3 powerlaw is assumed in order to compute the renormalized parameters. It has been shown that the RG fixed point is stable for ddc2.2d \ge d_c \approx 2.2. The renormalized viscosity ν\nu^* and resistivity η\eta^* have been calculated, and they are found to be positive for all parameter regimes. For σc=0\sigma_c=0 and large Alfv\'{e}n ratio (ratio of kinetic and magnetic energies) rAr_A, ν=0.36\nu^*=0.36 and η=0.85\eta^*=0.85. As rAr_A is decreased, ν\nu^* increases and η\eta^* decreases, untill rA0.25r_A \approx 0.25 where both ν\nu^* and η\eta^* are approximately zero. For large dd, both ν\nu^* and η\eta^* vary as d1/2d^{-1/2}. The renormalized parameters for the case σc1\sigma_c \to 1 are also reported.Comment: 19 pages REVTEX, 3 ps files (Phys. Plasmas, v8, 3945, 2001

    Fabrication and testing of a multifunctional SiO2@ZnO core-shell nanospheres incorporated polymer coating for sustainable marine transport

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    We report the development of a coating system relying on the incorporation of SiO2@ZnO coreshel nanospheres in polyurethane media as a novel approach to achieve longevity and sustainability in marine transport. This polymeric coating showed significant improvement in surface abrasion resistance, the transition from a hydrophilic state to a hydrophobic state (~125.2± 2°), improved antifungal, antibacterial and antialgae effects which make the proposed coating ideal to protect steel surfaces against biofouling. To substantiate our claims, we performed X-Ray diffraction, Transmission electron microscopy, Fourier transform infrared spectroscopy, scanning acoustic microscopy, Thermogravimetric analysis (TGA), contact angle measurements, antimicrobial (antialgal, antibacterial, antifungal) tests and Taber abrasion tests (ASTM D1044 and D4060) to highlight the mechanical and biological functionality as well as the bonding configuration of this coating. The wear analysis of the Taber abraded coating using SEM and optical microscopy showed significant improvement in the adhesion and shear resistance achieved by the SiO2@ZnO core-shell nanospheres incorporated PU coating which was a contrasting feature compared to using PU alone. The overall investigations we performed led us to find out that the addition of 4% (wt.) SiO2@ZnO core-shell nanoparticles to the PU media deposited on the low carbon steel surface demonstrated remarkable antimicrobial performance with almost no bacterial growth, significant reductions in growth for algae to about 9.2% and fungus to about 10.2%

    Acoustic-wave Amplification in Semiconductor

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    Two Stream Instabilities in Semiconductors Exhibiting Negative Differential Mobility

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    Scattering due to Plasmas

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