23 research outputs found

    Pediatric Fibromyxoma Maxilla – A rare entity

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    Fibromyxoma is a rare benign tumour of mesenchymal origin that mostly involves the posterior part of the mandible. It is a locally aggressive and slowly growing painless tumour that mostly occurs in second and third decades of life. We report a case of 2 years old child with huge mass of the right maxilla. After proper diagnosis mass was completely excised via sublabial approach and reported histopathologically as fibromyxoma. Because of its rarity in the maxilla and in this age, it is being reported here

    Phytochemical and Anti-Inflammatory Evaluation of Herbal Gel Prepared from Bark Extract of Mesua Ferrea Linn

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    The present research work involves formulation of herbal gel containing stem bark extracts of Mesua ferrea Linn and its evaluation for in vitro anti-inflammatory activity. The gel formulations were prepared using ethanolic extracts along with different polymer. The physiochemical parameters of formulations like; pH, viscosity and spreadability etc. also evaluated. Phytochemical analysis revealed presence of phenols, flavonoids and alkaloids, etc. The ethanolic extracts showed appreciable anti-inflammatory activity compared to the standard drug. Study confirmed that potential anti-inflammatory formulation can be developed from bark extract of Mesua ferrea Linn.   Keywords: Mesua ferrea Linn., Anti-inflammatory, Herbal Gel, Phytochemical, Albumin denaturation

    Genetic divergence, path coefficient and cluster analysis of French bean (Phaseolus vulgaris) genotypes

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    Thirty four pole type French bean (Phaseolus vulgaris L.) genotypes were evaluated to assess their genetic variability to identify desirable ones for yield and quality traits. The genotypic variance was moderate to high for the all the 14 traits studied, which resulted in high heritability and moderate to high genetic advance values. Pod yield/plant was positively correlated with all traits except days to 50% flowering, pod diameter and vitamin C content. High heritability and genetic advance of leaf width, first flowering node, number of seeds/pod, number of pods per plant, average pod weight and dry matter content vis-a-vis their positive association and direct positive effect on pod yield per plant suggested for their improvement through simple selection method. All the French bean genotypes were grouped into five distinct clusters. An analysis of the percentage contribution of individual characters towards genetic diversity revealed that vitamin C content, number of pods/plant and dry matter content were the major characters contributing to genetic diversity in French bean. Based on the finding it can concluded that French bean genotypes exhibited a wide range of variability for most of the traits. Some genotypes possessed desirable genes for more than one characters, hence may be utilized directly or included in hybridization programme

    Oxidative Stress in Neurodegenerative Diseases

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    Unusual occurrence of primary malignant melanoma of the nasal cavity

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    Malignant melanoma of nasal cavity is an extremely rare tumor with an incidence rate of 0.67% among all malignant melanomas. Melanomas are tumors arising from melanocytes that are neuroectodermal cells located in the basal layers of skin, skin adnexa, uveal tract, and occasionally in mucosal membranes. We report a case of malignant melanoma of nasal cavity in a 60-year-old female for its rare occurrence. These tumors have poor prognosis owing to high rates of locoregional recurrence and distant metastasis. We report this case without the symptom of epistaxis because of its rarity

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    Not AvailableEggplant (Solanum melongena L.) is an important solanaceous vegetable crop grown worldwide over tropics and subtropics. Bacterial wilt (caused by Ralstonia solanacearum) is one of the most serious diseases of the crop, especially in the humid tropics. The present investigation was carried out using 26 accessions of eggplant including wild relatives aiming to identify stable genotypes of eggplant with tolerant to bacterial wilt. The accessions were characterised using 40 simple sequence repeat (SSR) markers. Thirty-four markers were found polymorphic and produced 136 alleles with an average of four alleles per marker. All the markers have shown amplification across accessions of eggplant-related species. Markers EES- 050, EES-065, and EES-066 were highly informative. Among the species, scarlet eggplant (Solanum aethiopicum var.gilo) was found to be the closest to S.melongena. Markers, EES- 031 and EES-051, were specific to the accessions with tolerance to bacterial wilt. Based on the three-year evaluations, the disease incidence (DI) ranged from 1.27% (S.torvum) to 72.85% (S. melongena var. Kasi Taru). The AMMI and GGE biplot analyses have shown the significant contribution of genotype variation over the environment and interaction. The local eggplant accessions (Bhola Nath, RCMB-10, Singh Nath and RCMBL-1) were found highly stable for yield with lowest wilt incidences when compared to other Indian accessions. The results suggested the incorporation of local accessions/landraces into the eggplant breeding programmes aiming to develop stable cultivars with improved yield and resistant to bacterial wilt.Not Availabl

    Validation of a questionnaire to identify noise-induced hearing loss among drivers

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    Objective: To assess the validity of a questionnaire (consisting of 10 items/questions) to identify hearing loss (HL) among three-wheeler tempo and noncommercial car drivers. Materials and Methods: This was a cross-sectional study conducted in an urban area of Lucknow city. Three-wheeler tempo drivers and noncommercial car drivers were assessed for HL by audiometry. A total of 300 subjects, who fulfilled the study criteria, were selected for the interview and health assessment. The pure tone audiometry was conducted after >12 hours of the last noise exposure to avoid temporary threshold shift. Results: The percentage of respondents aged between 31 and 40 years was 36%. The highest affirmative response item was “Do you have trouble hearing in noisy background?” constituting 68% and the lowest affirmative response item was “Do you have trouble understanding the speech of women and children?” constituting 33.7%. Kappa values showed that there was significantly (<0.05) mild agreement between most of the items and the gold standard for mid and high-frequency HL. The area under the curve for low, mid, and high frequency HL was 0.76% (95% CI = 0.68–0.84), 0.69 (95% CI = 0.73–0.75), and 0.67 (95% CI = 0.62–0.73), respectively. The sensitivity and specificity were reasonable for all the definition of HL at different cutoff scores. Conclusion: A self-reported questionnaire-based approach may be used for the assessment of HL especially when audiometry is not feasible

    Effect of Varying Feeding Formulas on The Growth Performance of Buffalo Heifers

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    The present experiment was conducted at dairy farm during the year 2020-21 at CSAUA&amp;T Kanpur. The growth rate of buffalo heifers is a major problem at dairy farms. Twelve buffalo heifers were selected for digestibility that on a nutrition slide sample contains 86.50% DM, 20.10 %CP, 2.00 EE, 15.5% CF, 52.70% NFE and 9.50%Ash. The average dry matter intake per 100 kg body weight was (6.34, 5.44, 7.06 kg) the digestibility coefficient of DM was recorded (61.40, 59.95, 62.77) and digestibility coefficient of CP (63.55, 61.78, 65.77) and digestibility coefficient of CF (56.11, 54.75, 58.99) and digestibility coefficient of EE (64.89, 64.39, 67.52) and digestibility coefficient of NFE (64.06, 62.58, 65.75) and digestibility coefficient of Organic matter (64.45, 62.75, 66.99). The average live weight in buffalo heifers was increased (627.04, 610.44, 687.73) g per day in group I, II and III groups respectively. The growth parameters were statistically significant. Group III was shown better performance in respect of growth parameters in other groups I and II from the present study, it was apparent that the extra concentrate to be added in diet for proper development of growing heifers, III group was higher in growth. Digestibility coefficients of Dry matter, Crude Fiber, Ether extract, Nitrogen free extract and Organic matter were also higher in group III

    Post-Covid mucormycosis presenting as retropharyngeal abscess: a rare case report

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    Abstract Background Post-Covid retropharyngeal mucormycosis is a rare presentation, and no case has been reported in literature until date. Case presentation A-32-year-old female post Covid presented to our OPD with history of dysphagia and with a history of steroid intake. Radiology confirmed it as retropharyngeal abscess. Endoscopic-guided aspiration was done. HPE (histopathological examination) revealed classic broad aseptate hyphae of mucormycosis. Patient was managed conservatively with broad-spectrum antifungal. Conclusion Retropharyngeal mucormycosis is a rare entity in Covid era. Rapid diagnosis and management are needed to save life of an individual, or results could be fatal
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