A retrospective evaluation of patients with myelodysplastic syndrome

Aim: To determine our results by examining patient's files who we followed up by myelodysplastic syndrome (MDS) diagnosis between 2005 and 2009 as retrospectively and to compare the accordance of our results with literature. Methods: We examined 55 patient's files who got MDS diagnosis in 4 year-term. Complete blood count, biochemical analysis, peripheral spread, bone marrow aspiration, bone marrow biopsy examinations, cytogenetic and fluorescence in situ hybridization (FISH) analyses were made for all cases. Results: Our patient's age average was 69 and when classified according to WHO criterions at the diagnosis time, % 13 (23,6) of cases got diagnosed with RA-RARS, % 29 (52,7) with RCMD-RS, %5 (9,1) with RAEB-1, % 4 (7.3) with RAEB-2, % 3 (5.5) with MDS 5q and % 1 (1.8) with secondary MDS. % 52 of the patients had normal cytogenetic structure. No relation was determined between patients’ diagnosis and international prognostic scoring system (IPSS) scores. During the 4 year-term, our 13 patients died. 6 of these cases died by reason of transforming to acute myeloid leukemia (AML), and 7 patients died because of infection. Mean survival time of cases that died was 6 (1-7) months as of the diagnosis date. Whereas 8 cases were over 70 ages, 5 of our cases were under 70 ages. Conclusion: MDS is a disease that ranges between anemia and AML and requires cytogenetic trials for diagnosis along bone marrow aspiration and biopsy for the purpose of determining the treatment regimen and prognosis. Determining the IPSS scores of patients by obtained outcomes is required. Risk of transforming to acute leukemia and susceptibility to infection are important in terms of mortality. Overage of patient population restricts the treatment regimens. Age must be an important factor for prognosis and treatment choice. &nbsp

Uygulamadaki Beton Parke Taşlarının Mühendislik Özelliklerinin İncelenmesi

Beton kilitli parke taşları, son zamanlarda oldukça yaygın kullanılmaktadır. Özellikle şehir içi yol ve kaldırımlarda, araç park alanlarında, ticari merkezlerde, fabrika çevreleri ve benzeri yerlerde yoğun çalışmalara maruz kalan bölgelerde görülmektedir. Beton kilitli parke taşlarının özellikle standartta belirtilen minimum dayanımın üstünde olması gerekmektedir. Bu çalışmada, 5 farklı kullanım alanından ve her alan için 12 adet olmak üzere toplamda 60 adet beton kilitli parke taşı temin edilmiştir.  Temin edilen numunelerin TS 2824 EN1338 standardına uygun su emme ve dayanım özellikleri incelenmiştir. Numunelerden elde edilen sonuçlar standartta belirtilen sınır değerlerle karşılaştırılmıştır. Sonuç olarak bütün guruplarda su emme yüzdeleri standartta belirtilen sınır değerin altında olduğu görülmüştür. Dayanım değerlerinde ise gurup ortalama değerleri standarttın altında fakat yakın değerler elde edilmiştir

A Study on Composite Panels Prepared from Mixture of Mineral Adducts with Calabrian Pine Tree (Pinus brutia) Residues

The heat transfer coefficient values of 0.250 W/mK and l: 0.261 W/mK were found for Type 1 boards (bark based experimental boards of XBI and YBV)and l: 0.321 W/mK and l: 0.311 W/mK were found for Type 2 boards (cone based experimental boards of XCV and YCII), respectively. But all these are lower than standard value of 0.065 W/mK. However, visual evaluation show that all samples have low flame spreading properties which did not reach the threshold limit of 150 mm under a single flame combustion test. All Type 1 boards show lower mass loss (w, %) than control sample (B0: 11.97%), regardless of mineral additive type and proportions. The lowest mass loss of 6.36% was obtained with sample of YBIV. It is noticeable that olivine-cone (YC) and olivine-bark (YB) based panels usually show lower mass loss than dolomite-cone and dolomite-bark based panels at similar experimental conditions. The surface burning tests clearly indicate that the both mineral additions have lowering effects on burning feature of boards. This is probably olivine and dolomite could be absorbing heat and release water. Hence the burning area might become colder during evaporation of water with increasing charring and improve insulation of materials. The heat insulation levels of boards have found to be closely related with mineral content. But olivine seems to more effective for improving insulation properties for Type 1 boards. It is also found that both type panels (Type 1 and 2) which prepared from various proportions of dolomite and olivine as additives (10-50%) were show higher resistance against thermal degradation than control panels which prepared only (100%) from lignocellulosic material (cone and bark)

A Case of Vogt-Koyanagi-Harada Disease Associated With Polycystic Ovary Syndrome

We report a female patient diagnosed as Vogt-Koyanagi-Harada (VKH) and polycystic ovary syndrome (PCOS). She has diagnosed as VKH with diminished vision, bilateral serous retinal detachment, the signs of fundus fluorescein angiography and the findings of optical coherence tomography. The patient was referred to the gynecology clinic for her complaints as weight gain, hirsutismus and amenorrhea. She has also been diagnosed with PCOS. With oral steroid treatment, visual acuity has improved and the detachments have resolved within a month. VKH disease may be associated with polycystic ovary syndrome. The two conditions may have a common autoimmune pathogenesis

Treatment of adolescent idiopathic scoliosis with global (ROD) derotation maneuver using pedicle screws

Introduction: Adolescent idiopathic scoliosis is a three dimensional deformity. For the treatment of deformity, nature of deformity should be well understood and treatment strategy has to be directed to the coronal, sagittal and axial components of deformity. Global Derotation (GD) maneuver is based on simple rod derotation from concave side aiming to correct the deformity on coronal, sagittal and axial profile. In this report we reviewed AIS surgery results treated by global derotation maneuver with all pedicle screw instrumentation.Material& Methods: Between 2003 and 2011, 253 patients had been operated using GD technique.80 of 253 patients was included to our study. The patients routinely evaluated with preoperative-postoperative and last follow up standing ortho-x-rays. Coronal and sagittal profile parameters measured on x-rays with digital software using Cobb method. Rotational component of the deformity was measured according to Nash-Moe method at the apical vertebra.Results: 80 patients (71 female ; 9 male)had been followed up average 19,8 (7-37) months. Patients age average were 15,1(12-21) at operation date. Coronal cobb angle measure in thoracic curves preoperative were 48,9° decreased to mean 3,2° postoperatively. The mean coronal thoracolumbar curve were 45,8° preoperatively and decreased to mean 2°. Apical vertebra rotation measure regressed to mean 0,68 (0-1). Thoracic kyphosis showed downward tendency from mean 37,8° to mean 27,8°.Conclusion: Rod derotation technique enable to correct coronal and axial profile. Coronal Cobb angle improvement seen obviously with correction of axial profile rotation. Sagittal hypokyphotic effect of GD should be kept in mind

Farklı Tip Sıvaların Yüksek Sıcaklık ve Donma – Çözülme Etkisinde Mekanik Davranışı

Yapılarda duvar ve tavan elemanlarının kaplanmasında kullanılan sıvalar farklı özelliklere sahip olabilmektedir. Bu çalışmada, inşaatlarda yaygın olarak kullanılan üç farklı sıva karışımı (alçı, ısı yalıtım ve çimento esaslı sıva) üretici firma önerilerine uygun olarak 50x50x50 mm’lik kalıplara yerleştirilmiştir. Kalıplardan alınan numuneler 180 gün laboratuvar ortamında bekletilmiştir. Kür süreci sonunda numunelere 300-600 ve 900 ˚C yüksek sıcaklık ve 25-50 çevrim donma-çözülme etkisi uygulanmıştır. Ayrıca 50 çevrim donma – çözülme deneyine tabi tutulan numunelere daha sonra 900 ˚C yüksek sıcaklığa maruz bırakılmış ve numunelerin dayanım kayıpları incelenmiştir. Sonuç olarak; yüksek sıcaklık sonrası en az dayanım kayıpları 300 ve 600 ˚C’lerde çimento esaslı, 900 ˚C’de ise ısı yalıtım sıvalarında meydana gelmiştir. Donma- çözülme çevrimleri sonrasında en düşük dayanım kayıpları ısı yalıtım sıva numunelerinden elde edilmiştir

Unusual Suspect After Spinal Anesthesia: Herpetic Encephalitis

Herpes simplex virus (HSV) is the most common cause of acute, sporadic viral encephalitis. Usually occurs with the activation of the latent virus. Sudden onset fever and especially temporal lobe involvement are typical clinical features of HSV encephalitis. In this article, we aimed to present a case of herpetic encephalitis, which is an unusual factor in meningitis after spinal anesthesia. Severe headache and convulsion developed at postoperatively. Body temperature of the patient was 38.3 °C and neck stiffness developed. The patient was diagnosed with herpes encephalitis by clinical, laboratory and cranial magnetic resonance, and acyclovir treatment was started immediately. The patient was discharged home with recovery on the 14th day. Loss of consciousness and convulsions with fever seen at the postoperative period after spinal anesthesia, may not always be due to bacterial meningitis but sometimes due to HSV-associated acute herpetic meningoencephalitis. Rapid diagnosis and treatment is life-saving

Choroidal Thickness in Patients with Mild Cognitive Impairment and Alzheimer’s Type Dementia

Aim. To asses both choroidal thickness differences among Alzheimer’s type dementia (ATD) patients, mild cognitive impairment (MCI) patients, and healthy control (C) subjects and choroidal thickness relationships with cognitive performance. Methods. A total of 246 eyes of 123 people (41 ATD, 38 MCI, and 44 healthy C subjects) were included in this study. Complete ophthalmological and neurological examination was performed in all subjects. Choroidal thicknesses (CT) were measured at seven locations: the fovea, 500-1500-3000 μm temporal and 500-1500-3000 μm nasal to the fovea by enhanced depth imaging optical coherence tomography (EDI-OCT). Detailed neurological examination including mini mental state examination (MMSE) test which evaluates the cognitive function was applied to all participants. Results. The ages and genders of all participants were similar in all groups. Compared with healthy C subjects, the CT measurements at all regions were significantly thinner both in patients with ATD and in patients with MCI than in healthy C subjects (p<0.05). The MMSE scores were significantly different among ATD patients, MCI patients, and healthy C subjects. They were 19.3±1.8, 24.8±0.9, and 27.6±1.2 in ATD, MCI, and healthy controls, respectively (p<0.001). There were also significant correlation between MMSE score and choroidal thickness at each location (p<0.05). Conclusions. CT was reduced in ATD patients and MCI patients. Since vascular structures were affected in ATD patients and MCI patients, they had thin CT. Besides CT was correlated with degree of cognitive impairment. Therefore CT may be a new biomarker in diagnosis and follow-up of MCI and ATD patients