87 research outputs found
The electromagnetic effects in decay
The final state interaction of pions in decay allows one to obtain
the value of the isospin and angular momentum zero scattering length
.We take into account the electromagnetic interaction of pions and
isospin symmetry breaking effects caused by different masses of neutral and
charged pions and estimate the impact of these effects on the procedure of
scattering length extraction from decay.Comment: 8 pages,1 figur
The role of iron metabolism indicators in predicting gestational diabetes mellitus
Iron (Fe) deficiency and hyperglycaemia are both widely found throughout the world among pregnant women. According to the latest data from the American Diabetes Association (ADA), the prevalence of gestational diabetes mellitus (GDM) has increased and reaches 15–20%. Nowadays, there is growing evidence that a link between Fe metabolism and glucose homeostasis exists. The study of changes in the indicators of Fe metabolism in the serum of pregnant women with glucose intolerance and GDM plays an important role in expanding the understanding of the pathogenesis of these conditions. The hypothesis that excess Fe increases the risk of developing GDM has prompted us to review and evaluate the potential relationship between elevated Fe levels and the risk of developing GDM. The aim is to integrate all available data on the correlation between GDM and Fe status in the body. It is increasingly being recognised that excess Fe accumulation in the body is associated with an increased risk of diabetes. There is no available data on the relationship between serum ferritin and GDM in the Russian population, while early identification of the risk of GDM development will be of great importance for its related health effects and prevention. The role of Fe status as a GDM biomarker in high-risk populations is of interest, both for prognostic and diagnostic measures, and for therapeutic interventions. For a better understanding of whether an excess of Fe increases the risk of developing GDM, studies are needed to reveal the role of Fe in the mechanisms of GDM development
The isospin symmetry breaking effects in decays
The Fermi-Watson theorem is generalized to the case of two coupled channels
with different masses and applied to final state interaction in
decays. The impact of considered effect on the phase of the scattering
is estimated and shown that it can be crucial for scattering lengths extraction
from experimental data on decays
THz emission from Fe/Pt spintronic emitters with L1-FePt alloyed interface
Recent developments in nanomagnetism and spintronics have enabled the use of
ultrafast spin physics for terahertz (THz) emission. Spintronic THz emitters,
consisting of ferromagnetic FM / non-magnetic (NM) thin film heterostructures,
have demonstrated impressive properties for the use in THz spectroscopy and
have great potential in scientific and industrial applications. In this work,
we focus on the impact of the FM/NM interface on the THz emission by
investigating Fe/Pt bilayers with engineered interfaces. In particular, we
intentionally modify the Fe/Pt interface by inserting an ordered L1-FePt
alloy interlayer. Subsequently, we establish that a Fe/L1-FePt (2\,nm)/Pt
configuration is significantly superior to a Fe/Pt bilayer structure, regarding
THz emission amplitude. The latter depends on the extent of alloying on either
side of the interface. The unique trilayer structure opens new perspectives in
terms of material choices for the next generation of spintronic THz emitters
Acid-Base Properties Of Glass Substrate And SiO[2]-Bi[2]O[3]Thin-Film Systems Obtained On It
The article describes an experimental research as a result of which SiO[2]–Bi[2]O[3] films have been synthesized of film-forming solutions based on tetraethoxysilane and bismuth nitrate (III). Acid-base properties of a glass substrate and SiO[2]–Bi[2]O[3] films obtained on it have been studied. The dependency of physical and chemical properties of SiO[2]–Bi[2]O[3] composites on their percentage composition have been revealed
The activities of drug inactive ingredients on biological targets
Excipients, considered "inactive ingredients," are a major component of formulated drugs and play key roles in their pharmacokinetics. Despite their pervasiveness, whether they are active on any targets has not been systematically explored. We computed the likelihood that approved excipients would bind to molecular targets. Testing in vitro revealed 25 excipient activities, ranging from low-nanomolar to high-micromolar concentration. Another 109 activities were identified by testing against clinical safety targets. In cellular models, five excipients had fingerprints predictive of system-level toxicity. Exposures of seven excipients were investigated, and in certain populations, two of these may reach levels of in vitro target potency, including brain and gut exposure of thimerosal and its major metabolite, which had dopamine D3 receptor dissociation constant Kd values of 320 and 210 nM, respectively. Although most excipients deserve their status as inert, many approved excipients may directly modulate physiologically relevant targets
The potential risks and impact of the start of the 2015–2016 influenza season in the WHO European Region: a rapid risk assessment
Background: Countries in the World Health Organization (WHO) European Region are reporting more severe influenza activity in the 2015–2016 season compared to previous seasons. Objectives: To conduct a rapid risk assessment to provide interim information on the severity of the current influenza season. Methods: Using the WHO manual for rapid risk assessment of acute public health events and surveillance data available from Flu News Europe, an assessment of the current influenza season from 28 September 2015 (week 40/2015) up to 31 January 2016 (week 04/2016) was made compared with the four previous seasons. Results: The current influenza season started around week 51/2015 with higher influenza activity reported in Eastern Europe compared to Western Europe. There is a strong predominance of influenza A(H1N1)pdm09 compared to previous seasons, but the virus is antigenically similar to the strain included in the seasonal influenza vaccine. Compared to the 2014/2015 season, there was a rapid increase in the number of severe cases in Eastern European countries with the majority of such cases occurring among adults aged < 65 years. Conclusions: The current influenza season is characterized by an early start in Eastern European countries, with indications of a more severe season. Currently circulating influenza A(H1N1)pdm09 viruses are antigenically similar to those included in the seasonal influenza vaccine, and the vaccine is expected to be effective. Authorities should provide information to the public and health providers about the current influenza season, recommendations for the treatment of severe disease and effective public health measures to prevent influenza transmission
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