The range of LD in datasets using the CubeX tool to calculate r2 and D'

<p><b>Copyright information:</b></p><p>Taken from "Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'"</p><p>http://www.biomedcentral.com/1471-2105/8/428</p><p>BMC Bioinformatics 2007;8():428-428.</p><p>Published online 2 Nov 2007</p><p>PMCID:PMC2180187.</p><p></p> (A) Simulated data. D' on x-axis, ron y axis. (B) Real SNP data (Chr. 17:60 to 60.5 MB, 121 SNPs) from the HapMap project [23,24]. D' on x-axis, ron y axis

Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'-0

<p><b>Copyright information:</b></p><p>Taken from "Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'"</p><p>http://www.biomedcentral.com/1471-2105/8/428</p><p>BMC Bioinformatics 2007;8():428-428.</p><p>Published online 2 Nov 2007</p><p>PMCID:PMC2180187.</p><p></p>als. x-axis: allele frequency of SNP1, y-axis: allele frequency of SNP2. Black = more than one solution. Grey = one solution

Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'-4

<p><b>Copyright information:</b></p><p>Taken from "Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'"</p><p>http://www.biomedcentral.com/1471-2105/8/428</p><p>BMC Bioinformatics 2007;8():428-428.</p><p>Published online 2 Nov 2007</p><p>PMCID:PMC2180187.</p><p></p>als. x-axis: allele frequency of SNP1, y-axis: allele frequency of SNP2. Black = more than one solution. Grey = one solution

Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'-2

<p><b>Copyright information:</b></p><p>Taken from "Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'"</p><p>http://www.biomedcentral.com/1471-2105/8/428</p><p>BMC Bioinformatics 2007;8():428-428.</p><p>Published online 2 Nov 2007</p><p>PMCID:PMC2180187.</p><p></p>plotype frequencies (for the two solutions) displayed for comparison (lower table)