Two Compounds Constructed from Bimolybdenum-Capped Sandwich-Type Tetra-Ni-molybdogermanate and N‑Donor Multidentate Ligand

Two organic–inorganic hybrid bimolybdenum-capped tetra-Ni^II sandwich-type molybdogermanates, namely, (H₂L)₄[Ni₄(H₂O)₂­{B-α-GeMo₉O₃₄ (MoO₂)}₂]·6H₂O (<b>1</b>), [Ni₂(HL)₄(H₂O)₂]­[Ni₄(H₂O)₂­{B-α-GeMo₉O₃₄(MoO₂)}₂]·12H₂O (<b>2</b>), L = 2,4,5-tri­(4-pyridyl)­imidazole, were prepared with hydrothermal synthesis method and characterized by elemental analysis, IR spectroscopy, powder X-ray diffraction, thermogravimetric analysis, and single-crystal X-ray diffraction. Their magnetic properties and electrochemical properties were investigated. The results show that compounds <b>1</b> and <b>2</b> contain a new bimolybdenum-capped sandwich-type heteropolymolybdate anion, [Ni₄(H₂O)₂­{B-α-GeMo₉O₃₄(MoO₂)}₂]^8–. The compound <b>1</b> is a zero-dimensional supramolecular compound, and the supramolecular architecture of compound <b>2</b> is constructed from covalent layers through hydrogen bonds and π–π interaction. The two compounds both present electrocatalytic activities for the reduction of nitrite

Nucleic Acid and Nanomaterial Synergistic Amplification Enables Dual Targets of Ultrasensitive Fluorescence Quantification to Improve the Efficacy of Clinical Tuberculosis Diagnosis

Interferon-γ (IFN-γ) release assays (IGRAs) are constrained by the limited diagnostic performance of a single indicator and the excessive Mycobacterium tuberculosis (Mtb) antigen stimulation time. This study presents a simultaneous, homogeneous, rapid, and ultrasensitive fluorescence quantification strategy for IFN-γ and IFN-γ-induced protein 10 (IP-10). This method relies on the high-affinity binding of aptamers to IFN-γ and IP-10, the enzyme-free catalytic hairpin assembly reaction, and the heightened sensitivity of CdTe quantum dots to Ag+ and hairpin structure C-Ag+-C and carbon dots to Hg2+ and hairpin structure T-Hg2+-T. Under optimized conditions, the selectivity of IFN-γ and IP-10 was excellent, with a linear range spanning from 1 to 100 ag/mL and low limits of detection of 0.3 and 0.5 ag/mL, respectively. Clinical practicality was confirmed through testing of 57 clinical samples. The dual-indicator combination detection showed 92.8% specificity and 93.1% sensitivity, with an area under the curve of 0.899, representing an improvement over the single-indicator approach. The Mtb antigen stimulation time was reduced to 8 h for 6/7 clinical samples. These findings underscore the potential of our approach to enhance the efficiency and performance of a tuberculosis (TB) clinical diagnosis

Functionalized Pentamolybdodiphosphate-Based Inorganic–Organic Hybrids: Synthesis, Structure, and Properties

Three inorganic–organic hybrid compounds based on functionalized pentamolybdodiphosphonopropionate anion [(HO₂CC₂H₄PO₃)₂Mo₅O₁₅]^4–, [Co₃(bipy)₄(H₂O)₆{(HO₂CC₂H₄PO₃)₂Mo₅O₁₅}₂]·(H₂bipy)₂·18H₂O (<b>1</b>), [Fe₃(bipy)₄(H₂O)₆{(HO₂CC₂H₄PO₃)₂Mo₅O₁₅}₂]·(H₂bipy)₂·18H₂O (<b>2</b>), and [Cu­(bipy)­(H₂O)₂{(HO₂CC₂H₄PO₃)₂Mo₅O₁₅}]·(H₂bipy)·4H₂O (<b>3</b>), where bipy = 4,4′-bipyridine, have been successfully synthesized at different pH values in aqueous solutions. In compound <b>1</b>, [(HO₂CC₂H₄PO₃)₂Mo₅O₁₅]^4– acts as a tridentate ligand and coordinates to the Co²⁺ ions of trimeric complex cations [Co₃(bipy)₄(H₂O)₆]⁶⁺ forming a layer. In <b>3</b> [(HO₂CC₂H₄PO₃)₂Mo₅O₁₅]^4– acts as a bidentate ligand and coordinates to the Cu²⁺ ions of complex chains [Cu­(bipy)­(H₂O)₂]_<i>n</i>^2<i>n</i>+, forming a different layer from that in <b>1</b>. The three compounds were characterized by elemental analysis, IR spectra, and TGA. In addition, their fluorescent properties and magnetic properties have also been investigated

Photoexcited Single-Electron Transfer for Efficient Green Synthesis of Cyclic Carbonate from CO₂

It is attractive but challenging to produce high-value-added cyclic carbonates at ambient condition by the 100% atom-economic photocatalytic cycloaddition of CO2, which is limited by the insufficient understanding of the catalytic mechanism. Here, by taking Mg-MOF-74 as a model system, we propose the photoexcited catalyst can generally activate CO2 via single-electron-transfer mechanism, leading to the rapid formation of •CO2– radical. Subsequently, beneficial for the activation of inert CO2, the energy barrier of the rate-determining step (RDS) of the whole cycloaddition, i.e., the CO2 attacking step, significantly decreases, resulting in the feasible synthesis of cyclic carbonates under ambient condition. With the combination of synchrotron radiation in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS), in situ electron spin resonance (ESR) spectroscopy, and the density functional theory calculation, the reaction process and corresponding key intermediates are systematically investigated, revealing the CO2 activation to be the most energy consumption steps in cyclic carbonate production, rather than the ring-opening of epoxide, thus furnishing new insights into photocatalytic CO2 cycloaddition