Additional file 1 of The epidemiology of primary FSGS including cluster analysis over a 20-year period

Additional file 1: Supplement material 1. Raw anonymised data file of the 87 patients included within the study

ROC analysis: aβ₂GPI tests best discriminate for APS.

<p>Receiver operating characteristic (ROC) analysis was performed to assess the ability of each of the nine aPL assays to discriminate between APS and non-APS subjects. For all three antibody isotypes, the resulting ROC curves illustrate the superiority of aβ₂GPI tests compared to aCL and aDI for APS diagnosis (numerical results are listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0156407#pone.0156407.t003" target="_blank">Table 3</a>). Abbreviations: GPLU, MPLU, APLU: IgG/IgM/IgA phospholipid units respectively; GBU, MBU, ABU: IgG/IgM/IgA β₂GPI units respectively; GDIU, MDIU, ADIU: IgG/IgM/IgA DI units respectively.</p

Triple, double & single positivity per antibody isotype in APS.

<p>Triple, double & single positivity per antibody isotype in APS.</p

Demographic and clinical profile of subjects.

<p>Demographic and clinical profile of subjects.</p

Regression analysis: hazard ratio for APS.

<p>Regression analysis: hazard ratio for APS.</p

aPL activity and percentage of positivity in APS, SLE and HC groups.

<p>aPL activity and percentage of positivity in APS, SLE and HC groups.</p

ROC analysis: discriminatory ability of each aPL test for APS.

<p>ROC analysis: discriminatory ability of each aPL test for APS.</p