Additional file 4: Figure S3. of A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo

Virtual 4C output for the region around Ednrb gene in mouse genome (mm9 assembly). (PDF 308 kb

Additional file 2: Figure S1. of A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo

PCR experiments to confirm the deletion found in KFRS4/Kyo. (PDF 68 kb

Additional file 1: of Design and application of a target capture sequencing of exons and conserved non-coding sequences for the rat

Table S1. Summary statistics for SNV and INDEL in various depths. Figure S1. Sequence coverage of the target regions for each rat strain. Figure S2. Number of homozygous SNVs identified in WTC/Kyo and PVG/Seac strains for each genomic region. Figure S3. Proportion of the number of SNVs in terms of the each class of regions in the target, i.e., CDS, UTR, CNS, and other regions, for each rat strain. Figure S4. The relationship between the phastCons conservation score and SNV density for each rat strain. (PDF 215 kb

Additional file 3: Figure S2. of A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo

A KFRS4/Kyo-specific deletion of approximately 50 kb in length located approximately 50 kb upstream of Ednrb. (PDF 116 kb

Supple Fig:Table.pdf

This item contains supplementary figures and table of a manuscript 'Possible regulation of steroidogenic gene independent of Ad4BP/SF-1 (NR5A1)'

Superior Inorganic Ion Cofactors of Tetraborate Species Attaining Highly Efficient Heterogeneous Electrocatalysis for Water Oxidation on Cobalt Oxyhydroxide Nanoparticles

A heterogeneous catalyst incorporating an inorganic ion cofactor for electrochemical water oxidation was exploited using a CoO­(OH) nanoparticle layer-deposited electrode. The significant catalytic current for water oxidation was generated in a Na₂B₄O₇ solution at pH 9.4 when applying 0.94 V versus Ag/AgCl in contrast to no catalytic current generation in the K₂SO₄ solution at the same pH. HB₄O₇^– and B₄O₇^2– ions were indicated to act as key cofactors for the induced catalytic activity of the CoO­(OH) layer. The Na₂B₄O₇ concentration dependence of the catalytic current was analyzed based on a Michaelis–Menten-type kinetics to provide an affinity constant of cofactors to the active sites, <i>K</i>_m = 28 ± 3.6 mM, and the maximum catalytic current density, <i>I</i>_max = 2.3 ± 0.13 mA cm^–2. The <i>I</i>_max value of HB₄O₇^– and B₄O₇^2– ions was 1.4 times higher than that (1.3 mA cm^–2) for the previously reported case of CO₃^2– ions. This could be explained by the shorter-range proton transfer from the active site to the proton-accepting cofactor because of the larger size and more flexible conformation of HB₄O₇^– and B₄O₇^2– ions compared with that of CO₃^2– ions

Additional file 1: Table S1. of Association between off-hour presentation and endotracheal-intubation-related adverse events in trauma patients with a predicted difficult airway: A historical cohort study at a community emergency department in Japan

The ED census from 2007 to 2016. (DOCX 14 kb

Additional file 2: Figures S1–S8. of DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis

Figure S1: Expression of key molecular markers in isolated cells. Figure S2: CG methylation at ICRs and retrotransposons. Figure S3: PMD distribution in each chromosome. Figure S4: Replication-dependent loss of 5mC and 5hmC in neonatal spermatogonia after the resumption of mitosis. Figure S5: Changes in gene expression levels between stages. Figure S6: Genes involved in the signal transduction pathways for SSC self-renewal have stage-specific DMRs. Figure S7: Expression dynamics of transcription factors listed by motif analysis of the DMRs. Figure S8: Motifs found in the representative DMRs. (PDF 26886 kb

Additional file 6: Table S5. of DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis

GO terms enriched for the differentially expressed genes identified by DAVID analysis. (XLSX 78 kb