Iridium-Catalyzed Annulation of Salicylimines with 1,3-Dienes

Iridium-catalyzed annulation of salicylimines with 1,3-dienes gave high yields of the corresponding 4-aminochromanes with high stereoselectivity. The use of a chiral diene ligand enabled the asymmetric reaction to give 4-aminochromanes with high enantioselectivity

Iridium-Catalyzed Branch-Selective Hydroarylation of Vinyl Ethers via C–H Bond Activation

Iridium-catalyzed hydroarylation of vinyl ethers via a directed C–H bond activation of aromatic compounds gave high yields of the corresponding addition products with high branch selectivity

Selective H/D Exchange at Vinyl and Methylidene Groups with D₂O Catalyzed by an Iridium Complex

Selective H/D exchange at vinyl and methylidene groups of alkenes with D₂O was promoted by an iridium catalyst generated in situ from a hydroxoiridium complex and <i>N</i>-mesylbenzamide

Effect of Chiral Diene Ligands in Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to α,β-Unsaturated Sulfonyl Compounds

Asymmetric addition of arylboronic acids to α,β-unsaturated sulfonyl compounds proceeded in the presence of a rhodium catalyst coordinated with a chiral diene ligand to give high yields of the addition products with high enantioselectivity (96–>99.5% ee). The diene ligand was proved to be essential for the formation of the addition products, while the use of a bisphosphine ligand mainly gave the <i>cine</i>-substitution product

Cobalt-Catalyzed Asymmetric Addition of Silylacetylenes to 1,1-Disubstituted Allenes

The asymmetric addition of silylacetylenes to 1,1-disubstituted allenes proceeded in the presence of a cobalt/chiral bisphosphine ligand to give the corresponding enynes with high enantioselectivity. The results of deuterium-labeling experiments indicated that a hydrogen atom at the chiral center is originated from the terminal alkyne, and they were in good agreement with the proposed catalytic cycle where enantioselectivity is determined by the reaction of the proposed π-allylcobalt intermediate with the terminal alkyne

Iridium-Catalyzed Hydroarylation of Conjugated Dienes via π‑Allyliridium Intermediates

A hydroxoiridium/cod complex efficiently catalyzed hydroarylation of conjugated dienes with arenes bearing an acidic N–H bond as a directing group, which can form an amidoiridium species as an active intermediate for C–H activation. A π-allyliridium­(III) complex was isolated as a key intermediate leading to the addition product

Effect of Chiral Diene Ligands in Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to α,β-Unsaturated Sulfonyl Compounds

Asymmetric addition of arylboronic acids to α,β-unsaturated sulfonyl compounds proceeded in the presence of a rhodium catalyst coordinated with a chiral diene ligand to give high yields of the addition products with high enantioselectivity (96–>99.5% ee). The diene ligand was proved to be essential for the formation of the addition products, while the use of a bisphosphine ligand mainly gave the <i>cine</i>-substitution product

Effect of Chiral Diene Ligands in Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to α,β-Unsaturated Sulfonyl Compounds

Asymmetric addition of arylboronic acids to α,β-unsaturated sulfonyl compounds proceeded in the presence of a rhodium catalyst coordinated with a chiral diene ligand to give high yields of the addition products with high enantioselectivity (96–>99.5% ee). The diene ligand was proved to be essential for the formation of the addition products, while the use of a bisphosphine ligand mainly gave the <i>cine</i>-substitution product

Iridium-Catalyzed [3 + 2] Annulation of Cyclic <i>N</i>‑Sulfonyl Ketimines with 1,3-Dienes via C–H Activation

Ir-catalyzed [3 + 2] annulation of cyclic <i>N</i>-sulfonyl ketimines with 1,3-dienes, in which an aryliridium intermediate is formed via C–H activation, gives aminoindane derivatives in high yields with high regio- and diastereoselectivity

Silpha sabulosa

Ir-catalyzed [3 + 2] annulation of cyclic <i>N</i>-sulfonyl ketimines with 1,3-dienes, in which an aryliridium intermediate is formed via C–H activation, gives aminoindane derivatives in high yields with high regio- and diastereoselectivity