The cross-correlation search for a hot spot of gravitational waves : Numerical study for point spread function

The cross-correlation search for gravitational wave, which is known as 'radiometry', has been previously applied to map of the gravitational wave stochastic background in the sky and also to target on gravitational wave from rotating neutron stars/pulsars. We consider the Virgo cluster where may be appear as `hot spot' spanning few pixels in the sky in radiometry analysis. Our results show that sufficient signal to noise ratio can be accumulated with integration times of the order of a year. We also construct numerical simulation of radiometry analysis, assuming current constructing/upgrading ground-based detectors. Point spread function of the injected sources are confirmed by numerical test. Typical resolution of radiometry analysis is a few square degree which corresponds to several thousand pixels of sky mapping.Comment: 9 pages, 9 figures, Amaldi 9 & NRD

Cellular Control of Dengue Virus Replication: Role of Interferon-Inducible Genes

Dengue, one of the most common mosquito‐borne viral infectious diseases in the world, is caused by the dengue virus (DENV). This enveloped RNA virus has immunologically distinct serotypes that increase the risk of life‐threatening diseases, such as dengue haemorrhagic fever. However, no effective antiviral therapy against DENV infection has yet been established. As seen in other RNA viruses, various cellular factors have been reported to participate in efficient DENV replication. On the other hand, increasing recent evidence demonstrates that host cells harbour inhibitory factors that limit the DENV replication. In particular, it is well known that the response of interferons (IFNs), the first line of a host defence system against invading pathogens, evokes the expression of a number of genes that negatively regulate various steps of virus replication. This set of inhibitory genes, called interferon‐stimulated genes (ISGs), is considered to be a central force in IFN‐mediated antiviral responses. In this chapter, we focus our attention on the cellular factors involved in DENV infection, particularly to those that modulate DENV replication through their association with viral RNA. In addition, we also summarize general experimental approaches for identifying the host factors of RNA viruses, including DENV

A chi-squared time-frequency discriminator for gravitational wave detection

Searches for known waveforms in gravitational wave detector data are often done using matched filtering. When used on real instrumental data, matched filtering often does not perform as well as might be expected, because non-stationary and non-Gaussian detector noise produces large spurious filter outputs (events). This paper describes a chi-squared time-frequency test which is one way to discriminate such spurious events from the events that would be produced by genuine signals. The method works well only for broad-band signals. The case where the filter template does not exactly match the signal waveform is also considered, and upper bounds are found for the expected value of chi-squared.Comment: 18 pages, five figures, RevTex

Detecting gravitational waves from inspiraling binaries with a network of detectors : coherent strategies by correlated detectors

We discuss the coherent search strategy to detect gravitational waves from inspiraling compact binaries by a network of correlated laser interferometric detectors. From the maximum likelihood ratio statistic, we obtain a coherent statistic which is slightly different from and generally better than what we obtained in our previous work. In the special case when the cross spectrum of two detectors normalized by the power spectrum density is constant, the new statistic agrees with the old one. The quantitative difference of the detection probability for a given false alarm rate is also evaluated in a simple case.Comment: 4 pages, 1 Postscript figures, uses revtex4.st