Participant Characteristics according to the Number of Days Moving beyond the Neighborhood during One Week.

<p>IQR = interquartile range.</p><p>^a Kruskal Wallis.</p><p>^b Chi-square tests.</p><p>Participant Characteristics according to the Number of Days Moving beyond the Neighborhood during One Week.</p

Group Comparisons of Physical Activity according to the Number of Days Moving beyond the Neighborhood.

<p>M = Mean, 95%CI = 95% confidence interval.</p><p>^a Generalized Linear Models adjusted for accelerometer wear time.</p><p>^b Generalized Linear Models adjusted for accelerometer wear time + age + sex.</p><p>^c Generalized Linear Models adjusted for accelerometer wear time + age + sex + walking difficulty + monthly car driving.</p><p>^d Not adjusted for accelerometer wear time in any model.</p><p>Group Comparisons of Physical Activity according to the Number of Days Moving beyond the Neighborhood.</p

Proportion of Participants according to Greatest Life-Space Area and Frequency of Reaching Respective Area (N = 174).

<p>NOTE: Moving in the life-space areas inside (n = 1), outside (n = 1), neighborhood (n = 2) or beyond town (n = 2) for 6–7 days a week.</p

Within-Subject Comparison of Days on which a Participant Reached Different Life-Space Areas (N = 150).

<p>NOTE: General Estimating Equation models including participants who reached at least two different life-space areas during the assessment week. Statistically significant differences (p < .05) from average day “neighborhood” are indicated in bold.</p><p>b = regression coefficient, 95%CI = 95% confidence interval.</p><p>^a Adjusted for accelerometer wear time.</p><p>Within-Subject Comparison of Days on which a Participant Reached Different Life-Space Areas (N = 150).</p

Multinomial logistic regression analyses on baseline associations between perceived environmental barriers outdoors and mobility modifications and mobility difficulty among community-dwelling older people (n = 848).

<p>Multinomial logistic regression analyses on baseline associations between perceived environmental barriers outdoors and mobility modifications and mobility difficulty among community-dwelling older people (n = 848).</p

Number of perceived environmental barriers and mobility modification as predictors of incident mobility difficulty among community-dwelling older people without mobility difficulty at baseline (n = 492).

<p>Number of perceived environmental barriers and mobility modification as predictors of incident mobility difficulty among community-dwelling older people without mobility difficulty at baseline (n = 492).</p

Association between number of perceived environmental barriers outdoors and type of mobility modification among community-dwelling older people (n = 848).

<p>Association between number of perceived environmental barriers outdoors and type of mobility modification among community-dwelling older people (n = 848).</p

Baseline characteristics according to mobility categorizations among community-dwelling people (n = 848).

<p>Baseline characteristics according to mobility categorizations among community-dwelling people (n = 848).</p

Additional file 1: of Biological clocks and physical functioning in monozygotic female twins

Table S1. Differences between users and non-users from 24 twin pairs discordant for hormone replacement therapy. (DOCX 21 kb

Mean differences (Mdf), standard errors (SE), p values and partial correlations (r_Y⋅e) for genetic effects in age-adjusted models including COMT Val158Met polymorphism and physical activity for muscle CSA, hand grip strength, knee extension strength and leg extension power.

<p>sed = sedentary</p><p>mod = moderately active</p><p>act = active</p