Additional file 1: of Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition

The effect of SFN in cell viability of TGF-β1-stimulated cells for 24, 48, and 72 h. In A549 cells, TGF-β1 did not induce significant proliferation (A). TGF-β1-induced proliferation of MRC-5 cells showed inhibition by treatment of SFN for 1 h (B). (PDF 315 kb

Additional file 2: of Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition

Time response in the phosphorylation of SMAD2/3 by TGF-β1 and SFN treatment. In Western blotting of both A549 cells (A) and MRC-5 cells (B) showed phosphorylation of SMAD2/3 in early time within 1 h by TGF-β1. (PDF 113 kb