Исследование энергетических характеристик рентгеновской трубки

В настоящей работе приведены результаты исследования энергетических характеристикрентгеновской трубки Xstrahl300 путем моделирования процесса переноса тормозного излучения методом Монте-Карло, на котором основаны алгоритмы расчёта программы PC LAB. Показана возможность оценки распределения поглощенной дозы в различных точках координат водного фантома используя математическую модель. Таким образом, могут быть найдены оптимальные условия эксплуатации рентгеновской трубки в лучевой терапии при различных локализациях. Кроме того, математическая модель рентгеновского излучения способна моделировать ожидаемую эффективность проводимой терапии и относительную биологическую эффективность, используя теоретические модели

Biological-Based and Physical-Based Optimization for Biological Evaluation of Prostate Patient's Plans

Modern modalities of radiation treatment therapy allow irradiation of the tumor to high dose values and irradiation of organs at risk (OARs) to low dose values at the same time. In this paper we study optimal radiation treatment plans made in Monaco system. The first aim of this study was to evaluate dosimetric features of Monaco treatment planning system using biological versus dose-based cost functions for the OARs and irradiation targets (namely tumors) when the full potential of built-in biological cost functions is utilized. The second aim was to develop criteria for the evaluation of radiation dosimetry plans for patients based on the macroscopic radiobiological criteria - TCP/NTCP. In the framework of the study four dosimetric plans were created utilizing the full extent of biological and physical cost functions using dose calculation-based treatment planning for IMRT Step-and-Shoot delivery of stereotactic body radiation therapy (SBRT) in prostate case (5 fractions per 7 Gy)

Study of HeLa Cells Clone Survival after X-ray Irradiation in the Presence of Cisplatin

Radiation therapy in the presence of heavy elements nuclei (Z>53) is widely developed these days. The presence of such nuclei in cancer cells results in the local increase of energy release from primary photon beam thus increasing relative biological efficiency. In this paper we present the preliminary results of the cell survival study while irradiating cells by X-Ray photon beam in the presence of cisplatin (Pt, Z=78). The preliminary results show the decrease of the cell survival in the presence of both radiation and cisplatin

Study of HeLa Cells Clone Survival after X-ray Irradiation in the Presence of Cisplatin

Radiation therapy in the presence of heavy elements nuclei (Z>53) is widely developed these days. The presence of such nuclei in cancer cells results in the local increase of energy release from primary photon beam thus increasing relative biological efficiency. In this paper we present the preliminary results of the cell survival study while irradiating cells by X-Ray photon beam in the presence of cisplatin (Pt, Z=78). The preliminary results show the decrease of the cell survival in the presence of both radiation and cisplatin