81 research outputs found

    Conditional Complexity of Compression for Authorship Attribution

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    We introduce new stylometry tools based on the sliced conditional compression complexity of literary texts which are inspired by the nearly optimal application of the incomputable Kolmogorov conditional complexity (and presumably approximates it). Whereas other stylometry tools can occasionally be very close for different authors, our statistic is apparently strictly minimal for the true author, if the query and training texts are sufficiently large, compressor is sufficiently good and sampling bias is avoided (as in the poll samplings). We tune it and test its performance on attributing the Federalist papers (Madison vs. Hamilton). Our results confirm the previous attribution of Federalist papers by Mosteller and Wallace (1964) to Madison using the Naive Bayes classifier and the same attribution based on alternative classifiers such as SVM, and the second order Markov model of language. Then we apply our method for studying the attribution of the early poems from the Shakespeare Canon and the continuation of Marlowe’s poem ‘Hero and Leander’ ascribed to G. Chapman.compression complexity, authorship attribution.

    Molecular Characterization of Putative Chordoma Cell Lines

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    Immortal tumor cell lines are an important model system for cancer research, however, misidentification and cross-contamination of cell lines are a common problem. Seven chordoma cell lines are reported in the literature, but none has been characterized in detail. We analyzed gene expression patterns and genomic copy number variations in five putative chordoma cell lines (U-CH1, CCL3, CCL4, GB60, and CM319). We also created a new chordoma cell line, U-CH2, and provided genotypes for cell lines for identity confirmation. Our analyses revealed that CCL3, CCL4, and GB60 are not chordoma cell lines, and that CM319 is a cancer cell line possibly derived from chordoma, but lacking expression of key chordoma biomarkers. U-CH1 and U-CH2 both have gene expression profiles, copy number aberrations, and morphology consistent with chordoma tumors. These cell lines also harbor genetic changes, such as loss of p16, MTAP, or PTEN, that make them potentially useful models for studying mechanisms of chordoma pathogenesis and for evaluating targeted therapies

    Hepcidin and iron metabolism in preterm infants

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    Background: Iron deficiency (ID) and ID anemia are widespread in low-income countries, particularly among preterm infants. Hepcidin is a key regulator of iron metabolism, which offers the possibility of new solutions to diagnose ID in premature infants. Objective: To explore the relationship between iron metabolism and hepcidin in premature infants. Materials and methods: The study involved 81 preterm infants between 28+1 and 36+6 who underwent iron status indicators and hepcidin testing at 6 months of corrected gestational age. The preterm infants were divided into two groups based on iron status indicators: ID and no ID. Results: Serum hepcidin was lower for premature infants with ID compared to those without ID (log10hepcidin, 1.18 ± 0.44 vs 1.49 ± 0.37, p = 0.002). A single-variate linear regression model was used to explore the correlation between hepcidin and other indicators of iron metabolism. A strongly positive relationship was observed between hepcidin levels and ferritin levels (p < 0.001) in the correlation analysis. Conclusions: Hepcidin can be used as an efficient indicator of iron storage and a promising indicator for the early diagnosis of ID in premature infants

    Conditional Complexity of Compression for Authorship Attribution

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    Conditional Complexity of Compression for Authorship Attribution Abstract: We introduce new stylometry tools based on the sliced conditional compression complexity of literary texts which are inspired by the nearly optimal application of the incomputable Kolmogorov conditional complexity (and presumably approximates it). Whereas other stylometry tools can occasionally be very close for different authors, our statistic is apparently strictly minimal for the true author, if the query and training texts are sufficiently large, compressor is sufficiently good and sampling bias is avoided (as in the poll samplings). We tune it and test its performance on attributing the Federalist papers (Madison vs. Hamilton). Our results confirm the previous attribution of Federalist papers by Mosteller and Wallace (1964) to Madison using the Naive Bayes classifier and the same attribution based on alternative classifiers such as SVM, and the second order Markov model of language. Then we apply our method for studying the attribution of the early poems from the Shakespeare Canon and the continuation of Marlowe’s poem ‘Hero and Leander’ ascribed to G. Chapman

    Evaluation and optimization of ecological compensation fairness in prefecture-level cities of Anhui province

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    Scientific evaluation and continuous optimization of the fairness of ecological compensation are conducive to improving the effect of air pollution control. However, relevant research in this field is in its infancy. Based on the data on urban-scale PM _2.5 concentration and ecological compensation from the third quarter of 2018 to the fourth quarter of 2020, this study takes 16 prefecture-level cities in Anhui Province as the research area and uses the Granger causality test to determine the PM _2.5 overflow paths of each city. Moreover, using 2020 as an example, the PM _2.5 spillover effect of each city is calculated, and the haze Gini coefficient of Anhui Province is obtained. According to the empirical results, the ecological compensation policy for PM _2.5 control in Anhui Province is in a relatively equal fairness range (0.295). On this basis, combined with the scatter diagram of ecological compensation and spillover effect, it is suggested to reduce the ecological compensation of five cities, including Maanshan and Xuancheng, while the ecological compensation of the remaining 11 cities should be increased. Two feasible optimization schemes, i.e., annual adjustment and regular adjustment, are proposed for environmental regulators to choose

    Dynamic Coupling Trajectory and Spatial-Temporal Characteristics of High-Quality Economic Development and the Digital Economy

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    This paper takes China’s 2014–2019 provincial data as the observation sample to explore the dynamic coupling law of the digital economy and high-quality economic development. First, using the coupling coordination model, it is found that the coupling coordination degree of the digital economy and high-quality economic growth is on an upward trend, and the coupling coordination degree in the eastern region is higher than that in other regions; then, using Markov chain algorithm, it is found that the coupling coordination degree in the east of region achieves a two-level leap of “antagonism stage-running-in stage-coordination stage”, while the central and western regions accomplish a single level of “antagonism stage-running-in stage” leap. Finally, using the Dagum Gini coefficient decomposition method, it was found that the mean values of inter-regional, intra-regional, and supervariate density differences in coupling coordination contributed 67.60%, 24.03%, and 8.36% to the overall differences, respectively, with highly moderate fluctuations. The general, inter-regional and intra-regional differences all show a decreasing trend, but there is heterogeneity in their corresponding variation characteristics. This paper provides substantial empirical evidence for exploring the inherent laws and provides an essential guarantee for China’s regional economy’s comprehensive, coordinated, and sustainable development

    Efficient Production of N-Butyl Levulinate Fuel Additive from Levulinic Acid Using Amorphous Carbon Enriched with Oxygenated Groups

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    The aim of this study was to develop an effective carbonaceous solid acid for synthesizing green fuel additive through esterification of lignocellulose-derived levulinic acid (LA) and n-butanol. Two different sulfonated carbons were prepared from glucose-derived amorphous carbon (GC400) and commercial active carbon (AC400). They were contrastively studied by a series of characterizations (N-2 adsorption, X-ray diffraction, elemental analysis, transmission electron microscopy, Fourier transform infrared spectroscopy and NH3 temperature programmed desorption). The results indicated that GC400 possessed stronger acidity and higher -SO3H density than AC400, and the amorphous structure qualified GC400 for good swelling capacity in the reaction solution. Assessment experiments showed that GC400 displayed remarkably higher catalytic efficiency than AC400 and other typical solid acids (HZSM-5, H, Amberlyst-15 and Nafion-212 resin). Up to 90.5% conversion of LA and 100% selectivity of n-butyl levulinate could be obtained on GC400 under the optimal reaction conditions. The sulfonated carbon retained 92% of its original catalytic activity even after five cycles

    Enhancement of biocontrol efficacy of Cryptococcus laurentii by cinnamic acid against Penicillium italicum in citrus fruit

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    Cinnamic acid was effective to control blue mold caused by Penicillium italicum in 'Orah' mandarins. The inhibition of fruit decay was positively correlated with cinnamic acid concentration. Cinnamic acid at 1.5 mM, in combination with the biocontrol yeast Cryptococcus laurentii at 1 x 10(7) cells/mL, provided synergistic effects against P. italicum. Population dynamic analysis demonstrated that the growth of C. laurentii in fruit rind wounds was not significantly influenced by cinnamic acid. C. laurentii multiplied rapidly, regardless of whether the yeast was used alone or combined with cinnamic acid. By contrast, spore germination and mycelial growth of P. italicum in the culture medium were markedly inhibited by cinnamic acid. By using propidium iodide fluorescent staining, loss of membrane integrity in P. italicum was observed after cinnamic acid treatment. Furthermore, cinnamic acid led to the leakage of cellular constituents including soluble proteins and carbohydrates from hyphae of P. italicum. These results indicated that the fungal pathogen P. italicum is more sensitive to cinnamic acid than the biocontrol yeast C. laurentii. Taken together, our data suggest that the enhancement in biocontrol efficacy of C. laurentii might be associated with the differential influence of cinnamic acid on the antagonistic yeast and the fungal pathogen
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