Detection, attribution, and sensitivity of trends toward earlier streamflow in the Sierra Nevada

Observed changes in the timing of snowmelt dominated streamflow in the western United States are often linked to anthropogenic or other external causes. We assess whether observed streamflow timing changes can be statistically attributed to external forcing, or whether they still lie within the bounds of natural (internal) variability for four large Sierra Nevada (CA) basins, at inflow points to major reservoirs. Streamflow timing is measured by “center timing” (CT), the day when half the annual flow has passed a given point. We use a physically based hydrology model driven by meteorological input from a global climate model to quantify the natural variability in CT trends. Estimated 50-year trends in CT due to natural climate variability often exceed estimated actual CT trends from 1950 to 1999. Thus, although observed trends in CT to date may be statistically significant, they cannot yet be statistically attributed to external influences on climate. We estimate that projected CT changes at the four major reservoir inflows will, with 90% confidence, exceed those from natural variability within 1–4 decades or 4–8 decades, depending on rates of future greenhouse gas emissions. To identify areas most likely to exhibit CT changes in response to rising temperatures, we calculate changes in CT under temperature increases from 1 to 5°. We find that areas with average winter temperatures between −2°C and −4°C are most likely to respond with significant CT shifts. Correspondingly, elevations from 2000 to 2800 m are most sensitive to temperature increases, with CT changes exceeding 45 days (earlier) relative to 1961–1990

Development and application of a hydroclimatological stream temperature model within the Soil and Water Assessment Tool

We develop a stream temperature model within the Soil and Water Assessment Tool (SWAT) that reflects the combined influence of meteorological (air temperature) and hydrological conditions (streamflow, snowmelt, groundwater, surface runoff, and lateral soil flow) on water temperature within a watershed. SWAT currently uses a linear air-stream temperature relationship to determine stream temperature, without consideration of watershed hydrology. As SWAT uses stream temperature to model various in-stream biological and water quality processes, an improvement of the stream temperature model will result in improved accuracy in modeling these processes. The new stream temperature model is tested on seven coastal and mountainous streams throughout the western United States for which high quality flow and water temperature data were available. The new routine does not require input data beyond that already supplied to the model, can be calibrated with a limited number of calibration parameters, and achieves improved representation of observed daily stream temperature. For the watersheds modeled, the Nash-Sutcliffe (NS) coefficient and mean error (ME) for the new stream temperature model averaged 0.81 and −0.69°C, respectively, for the calibration period and 0.82 and −0.63°C for the validation period. The original SWAT stream temperature model averaged a NS of −0.27 and ME of 3.21°C for the calibration period and a NS of −0.26 and ME of 3.02°C for the validation period. Sensitivity analyses suggest that the new stream temperature model calibration parameters are physically reasonable and the model is better able to capture stream temperature changes resulting from changes in hydroclimatological conditions

Climate change and stream temperature projections in the Columbia River basin: habitat implications of spatial variation in hydrologic drivers

Water temperature is a primary physical factor regulating the persistence and distribution of aquatic taxa. Considering projected increases in air temperature and changes in precipitation in the coming century, accurate assessment of suitable thermal habitats in freshwater systems is critical for predicting aquatic species\u27 responses to changes in climate and for guiding adaptation strategies. We use a hydrologic model coupled with a stream temperature model and downscaled general circulation model outputs to explore the spatially and temporally varying changes in stream temperature for the late 21st century at the subbasin and ecological province scale for the Columbia River basin (CRB). On average, stream temperatures are projected to increase 3.5 °C for the spring, 5.2 °C for the summer, 2.7 °C for the fall, and 1.6 °C for the winter. While results indicate changes in stream temperature are correlated with changes in air temperature, our results also capture the important, and often ignored, influence of hydrological processes on changes in stream temperature. Decreases in future snowcover will result in increased thermal sensitivity within regions that were previously buffered by the cooling effect of flow originating as snowmelt. Other hydrological components, such as precipitation, surface runoff, lateral soil water flow, and groundwater inflow, are negatively correlated to increases in stream temperature depending on the ecological province and season. At the ecological province scale, the largest increase in annual stream temperature was within the Mountain Snake ecological province, which is characterized by migratory coldwater fish species. Stream temperature changes varied seasonally with the largest projected stream temperature increases occurring during the spring and summer for all ecological provinces. Our results indicate that stream temperatures are driven by local processes and ultimately require a physically explicit modeling approach to accurately characterize the habitat regulating the distribution and diversity of aquatic taxa

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Projections of 21st Century Sierra Nevada Local Hydrologic Flow Components Using an Ensemble of General Circulation Models

Sierra Nevada snowmelt and runoff is a key source of water for many of California’s 38 million residents and nearly the entire population of western Nevada. The purpose of this study was to assess the impacts of expected 21st Century climatic changes in the Sierra Nevada at the subwatershed scale, for all hydrologic flow components, and for a suite of 16 General Circulation Models (GCMs) with two emission scenarios. The Soil and Water Assessment Tool (SWAT) was calibrated and validated at 35 unimpaired streamflow sites. Results show that temperatures are projected to increase throughout the Sierra Nevada, whereas precipitation projections vary between GCMs. These climatic changes drive a decrease in average annual streamflow and an advance of snowmelt and runoff by several weeks. The largest streamflow reductions were found in the mid-range elevations due to less snow accumulation, whereas the higher elevation watersheds were more resilient due to colder temperatures. Simulation results showed that decreases in snowmelt affects not only streamflow, but evapotranspiration, surface, and subsurface flows, such that less water is available in spring and summer, thus potentially affecting aquatic and terrestrial ecosystems. Declining spring and summer flows did not equally affect all subwatersheds in the region, and the subwatershed perspective allowed for identification for the most sensitive basins throughout the Sierra Nevada

Effects of climate change on stream temperature, dissolved oxygen, and sediment concentration in the Sierra Nevada in California

Warmer temperatures are expected to raise mountain stream temperatures, affecting water quality and ecosystem health. We demonstrate the importance of climate-driven changes in hydrology as fundamental to understanding changes in the local water quality. In particular, we focus on changes in stream temperature, dissolved oxygen (DO) concentrations, and sediment transport in mountainous, snowmelt-dominated, and water-limited systems, using the Sierra Nevada as our case study. Downscaled output from an ensemble of general circulation model projections for the A2 (higher greenhouse gas) emission scenario was used to drive the Soil and Water Assessment Tool with a new integrated stream temperature model on the subbasin scale. Spring and summer stream temperature increase by 1°C–5.5°C, with varying increases among subbasins. The highest projected stream temperatures are in the low-elevation subbasins of the southern Sierra Nevada, while the northern Sierra Nevada, with distinct impacts on snowmelt and subsurface flow contributions to streamflow, shows moderated increases. The spatial pattern of stream temperature changes was the result of differences in surface and subsurface hydrologic, snowmelt, and air temperature changes. Concurrent with stream temperature increases and decreases in spring and summer flows, simulations indicated decreases in DO (10%) and sediment (50%) concentrations by 2100. Stream temperature and DO concentrations for several major streams decline below survival thresholds for several native indicator species. These results highlight that climatic changes in water-limited mountain systems may drive changes in water quality that have to be understood on the reach scale for developing adaptive management options

Effects of projected climate change on the hydrology in the Mono Lake Basin, California

The Californian Mono Lake Basin (MLB) is a fragile ecosystem, for which a 1983 ruling carefully balanced water diversions with ecological needs without the consideration of global climate change. The hydroclimatologic response to the impact of projected climatic changes in the MLB has not been comprehensively assessed and is the focus of this study. Downscaled temperature and precipitation projections from 16 Global Climate Models (GCMs), using two emission scenarios (B1 and A2), were used to drive a calibrated Soil and Water Assessment Tool (SWAT) hydrologic model to assess the effects on streamflow on the two significant inflows to the MLB, Lee Vining and Rush Creeks. For the MLB, the GCM ensemble output suggests significant increases in annual temperature, averaging 2.5 and 4.1 °C for the B1 and A2 emission scenarios, respectively, with concurrent small (1–3 %) decreases in annual precipitation by the end of the century. Annual total evapotranspiration is projected to increase by 10 mm by the end of the century for both emission scenarios. SWAT modeling results suggest a significant hydrologic response in the MLB by the end of the century that includes a) decreases in annual streamflow by 15 % compared to historical conditions b) an advance of the peak snowmelt runoff to 1 month earlier (June to May), c) a decreased (10–15 %) occurrence of ‘wet’ hydrologic years, and d) and more frequent (7–22 %) drought conditions. Ecosystem health and water diversions may be affected by reduced water availability in the MLB by the end of the century

Projected 21st-century changes in the Central American mid-summer drought using statistically downscaled climate projections

In addition to periodic long-term drought, much of Central America experiences a rainy season with two peaks separated by a dry period of weeks to over a month in duration, termed the mid-summer drought (MSD). Farmers in the region have adapted their activities to accommodate this phenomenon, anticipating its arrival and estimating its duration. Among the many impacts of global warming on the region are projected changes in precipitation amount, variability, and timing, with potential to affect agriculture and food security. Using gridded daily precipitation for a historic period with future projections, we characterize the MSD across much of Central America using four measures: onset date, duration, intensity, and minimum, and test for significant changes by the end of the twenty-first century. Our findings indicate that the most significant changes are for the duration, which is projected to increase by an average of over a week, and the MSD minimum precipitation, which is projected to decrease by an average of over 26%, with statistically significant changes for the mountains and Pacific side in most of Nicaragua, Honduras, El Salvador, and Guatemala (assuming a higher emissions pathway through the twenty-first century). These changes could portend important impacts on food security for vulnerable communities through the region. We find that for the four metrics, the changes in interannual variability are small compared to historical variability and are generally statistically insignificant

Assessing differences in snowmelt-dependent hydrologic projections using CMIP3 and CMIP5 climate forcing data for the western United States

Most recent climate change impact studies are using Coupled Model Intercomparison Project Phase 5 (CMIP5) projections to replace older generation CMIP3 projections. Here we evaluate whether differences between projections based on comparable high emission pathways of a seven-member general circulation model CMIP3 versus CMIP5 ensemble change our understanding of the expected hydrologic impacts. This work focuses on the important snowmelt-dominated mountain runoff-generating regions of the western United States (WUS; Upper Colorado River Basin (UCRB), Columbia River Basin (CRB), and Sierra Nevada (SN) Basins). Significant declines in snowmelt, and shifts in streamflow timing owing to warmer, wetter CMIP5 projections match or exceed those based on CMIP3 throughout the WUS. CMIP3- and CMIP5-based projections, while generally in agreement about hydroclimatic changes, differ in some important aspects for key regions. The most important is the UCRB, where CMIP5-based projections suggest increases in future streamflows. Comparable hydrologic projections result from similar underlying climate signals in CMIP3 and CMIP5 output for the CRB and SN, suggesting that previous work completed in these basins based on CMIP3 projections is likely still useful. However, UCRB hydrologic projections based on CMIP5 output suggest that a re-evaluation of future impacts on water resources is warranted