1,241 research outputs found

    MIS Faculty Perceptions Regarding the Reengineered Organizational & End-User Information Systems Curriculum in Information Technology Education

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    A report submitted by C. Steven Hunt to the Research and Creative Research Committee on the use of organizational computing for providing enhanced productivity at the desktop level and the competitive advantage of current IT implementations

    Research On The Value Of AACSB Business Accreditation In Selected Areas: A Review And Synthesis

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    The AACSB claims that its accreditation provides evidence of business school quality in a variety of areas. This paper reviews and synthesizes existing research on the value of AACSB accreditation on four key topics of importance to schools, prospective students, and employers: effect on obtaining quality students, students’ job placement, faculty recruitment, and teaching quality. The very limited research comparing AACSB to other business accreditation is also examined.  Overall, the analysis indicates very mixed support, at best, for the claims of AACSB schools’ superiority in these areas. This analysis should be useful for business schools, employers, and prospective business students

    Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR.

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    Telomere length/DNA content has been measured in epidemiological/clinical settings with the goal of testing a host of hypotheses related to the biology of human aging, but often the conclusions of these studies have been inconsistent. These inconsistencies may stem from various reasons, including the use of different telomere length measurement techniques. Here, we report the first impartial evaluation of measurements of leukocyte telomere length by Southern blot of the terminal restriction fragments and quantitative PCR (qPCR) of telomere DNA content, expressed as the ratio of telomeric product (T)/single copy gene (S) product. Blind measurements on the same samples from 50 donors were performed in two independent laboratories on two different occasions. Both the qPCR and Southern blots displayed highly reproducible results as shown by r values > 0.9 for the correlations between results obtained by either method on two occasions. The inter-assay CV measurement for the qPCR was 6.45%, while that of the Southern blots was 1.74%. The relation between the results generated by Southern blots versus those generated by qPCR deviated from linearity. We discuss the ramifications of these findings with regard to measurements of telomere length/DNA content in epidemiological/clinical circumstances

    Association of egg consumption and calcified atherosclerotic plaque in the coronary arteries: The NHLBI Family Heart Study

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    pre-printBackground and Aims: Eggs are a ubiquitous and important source of dietary cholesterol and nutrients, yet their relationship to coronary heart disease (CHD) remains unclear. While some data have suggested a positive association between egg consumption and CHD, especially among diabetic subjects, limited data exist on the influence of egg consumption on subclinical disease. Thus, we sought to examine whether egg consumption is associated with calcified atherosclerotic plaques in the coronary arteries. Methods: In a cross-sectional design, we studied 1848 participants of the NHLBI Family Heart Study without known CHD. Egg consumption was assessed by a semi-quantitative food frequency questionnaire and coronary-artery calcium (CAC) was measured by cardiac CT. We defined prevalent CAC using an Agatston score of at least 100 and fitted generalized estimating equations to calculate prevalence odds ratios of CAC. Results: Mean age was 56.5 years and 41% were male. Median consumption of eggs was 1/week. There was no association between frequency of egg consumption and prevalent CAC. Odds ratios (95% CI) for CAC were 1.0 (reference), 0.95 (0.66-1.38), 0.94 (0.63-1.40), and 0.90 (0.57-1.42) for egg consumption of almost never, 1-3 times per month, once per week, and 2+ times per week, respectively (p for trend 0.66), adjusting for age, sex, BMI, smoking, alcohol, physical activity, income, field center, total calories, and bacon

    Genetics and geography of leukocyte telomere length in sub-Saharan Africans

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    Leukocyte telomere length (LTL) might be causal in cardiovascular disease and major cancers. To elucidate the roles of genetics and geography in LTL variability across humans, we compared LTL measured in 1295 sub-Saharan Africans (SSAs) with 559 African-Americans (AAms) and 2464 European-Americans (EAms). LTL differed significantly across SSAs (P = 0.003), with the San from Botswana (with the oldest genomic ancestry) having the longest LTL and populations from Ethiopia having the shortest LTL. SSAs had significantly longer LTL than AAms [P = 6.5(e-16)] whose LTL was significantly longer than EAms [P = 2.5(e-7)]. Genetic variation in SSAs explained 52% of LTL variance versus 27% in AAms and 34% in EAms. Adjustment for genetic variation removed the LTL differences among SSAs. LTL genetic variation among SSAs, with the longest LTL in the San, supports the hypothesis that longer LTL was ancestral in humans. Identifying factors driving LTL variation in Africa may have important ramifications for LTL-associated diseases

    Perceptions And Validation Of Key Information Technology Competencies From An IT Alumni Viewpoint: Another Stakeholder In The Curriculum Design Process

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    The objective of this research was to determine the perceptions of End-user Information Systems graduates from selected universities (now alumni status) regarding an updated Organizational & End-user Information Systems (OEIS) curriculum sponsored by the Organizational Systems Research Association now referred to as AIS-SIG OSRA.  The study included the following research objectives:  (1) to determine the perceived level of importance of the OEIS curriculum content in today’s global workforce and (2) to ascertain the information systems (IS) personnel viewpoints on the overall importance of the specific course objectives.  Survey findings revealed specific topics are of critical and/or considerable importance upon graduation from an end-user information systems-related program.  An understanding of the systems development life cycle (SDLC) including planning and implementation of end-user support systems in combination with troubleshooting skills were perceived to be noted essential components of an IT curriculum.  Moreover, an experiential learning/internship experience—similar to a clinical practicum--was deemed to be of critical importance for information technology (IT) professionals.  To further validate the model, it is recommended that universities in other regions of the United States survey their alumni to assess what specific IS & IT objectives and skill sets are currently needed, especially given the exponential demand for trained personnel in emerging areas of health information technology, enterprise systems, project management, virtualization,  and information assurance

    MIS Faculty Perceptions Regarding The Reengineered Organizational & End-User Information Systems Curriculum In Information Technology Education

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    The Office Systems Research Association’s recent revision of the Organizational End-User Information Systems (OEIS) curriculum model provides an opportune setting for determining the value of the model regarding undergraduate education in end-user information systems. This study follows an established method for examining IS curriculum perceptions by MIS faculty in hopes of providing a realistic snapshot of the model’s strengths and weaknesses to aid the actual decision and implementation process of end-user information systems undergraduate curricula. Key findings regarding the perceived importance of the curriculum objectives are reported as well as conclusions, implications and suggestions for future research in end-user information systems.  Feedback from MIS faculty regarding possible methods for integrating enterprise systems concepts (ERP) are also reported. MIS academicians have shown that the model curriculum and the associated content objectives do indeed have value and is of considerable importance. In addition to its importance, the faculty validated and solidified that the curriculum does have merit in preparing OEIS undergraduate students for participation, as end user support personnel, in a digital, knowledge-based economy of unbridled change

    The Effect Of Gender And Knowledge On Students Impressions Of Accountants In The Post-Enron Era

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    This study examines college students’ impressions of accountants from various sources. It extends previous research on students’ impressions of accountants by analyzing impressions after Enron, gender differences in impressions, and the effect of knowledge on impressions and adding news reports as an impression source. Students rated their impressions of accountants when they selected a major on each of 30 characteristics (such as ethical, versatile, and exciting) from each of four sources, plus a general rating. When qualities were combined into two factors, Professionalism and Personability, accountants were seen as professional, but not particularly personable. In many areas, finance majors had impressions of accountants equal to or higher than those of accounting students, while other majors had significantly lower impressions of accountants. News reports did not significantly influence students’ views of accountants. Knowledge was strongly correlated with impressions. Accounting students had the lowest knowledge of accountants from news reports and movies/TV of any major. Females held more positive impressions of accountants than did males. Implications for various groups, including college and high school accounting education and the accounting profession, are discussed

    ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes

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    Journal ArticleAdipose triglyceride lipase (ATGL) was recently described to predominantly perform the initial step in triglyceride hydrolysis and therefore seems to play a pivotal role in the lipolytic catabolism of stored fat in adipose tissue. In the first study investigating genetic variations within the ATGL gene in humans, 12 polymorphisms identified via sequencing and database search were studied in 2,434 individuals of European ancestry from Utah. These polymorphisms and their haplotypes were analyzed in subjects not taking diabetes medication for association with plasma free fatty acids (FFAs) as primary analysis, as well as triglycerides and glucose as a secondary analysis (n = 1,701, 2,193, or 2,190, respectively). Furthermore, type 2 diabetes (n = 342 of 2,434) was analyzed as an outcome. FFA concentrations were significantly associated with several single nucleotide polymorphisms (SNPs) of ATGL (P values from 0.015 to 0.00003), consistent with additive inheritance. The pattern was similar when considering triglyceride concentrations. Furthermore, two SNPs showed associations with glucose levels (P < 0.00001) and risk of type 2 diabetes (P < 0.05). Haplotype analysis supported and extended the shown SNP association analyses. These results complement previous findings of functional studies in mammals and elucidate a potential role of ATGL in pathways involved in components of the metabolic syndrome
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