Changes in biochemistry, catecholamines and haematocrit in the endotoxin group.

<p>Interquartile ranges [IQR] and standard deviations are shown (SD) according to the distribution of the variables.</p>*<p>p<0.05,</p>¤<p>p<0.01.</p

Changes in haemodynamic parameters for the control; hypovolaemia and endotoxaemia rabbits.

<p>The central bar is the mean, the box represents the inter-quartile range and the whiskers the range. Significant differences between the control and experimental groups of p<0.05 are noted by an ‘*’ and p<0.01 by an ‘¤’.</p

Gant chart showing schema of blood sampling and electrical stimulation.

<p>Control rabbits and the experimental groups all received the same number of stimulations and blood samples. Endotoxaemic rabbits had five stimulations and three blood samples that were not analysed, as according to protocol, so as to ensure identical experimental conditions for all groups.</p

Changes in biochemistry, catecholamines and haematocrit in the hypovolaemic rabbits.

<p>Interquartile ranges [IQR] and standard deviations are shown (SD) according to the distribution of the variables.</p>*<p>p<0.05,</p>¤<p>p<0.01.</p

Population characteristics for all patients and the two age sub-groups of neonates and older children.

<p>All of the variables from the columns ‘All Patients’ were entered into the propensity score. the PRISM score was not used for the propensity score. Neonates are ≤28 days and older children >28 days and less than 8 years.</p>*<p>p value <0.05 for the difference between the atropine and non-atropine groups.</p><p>NRD - neonatal respiratory distress, Non-NRD - non-neonatal respiratory distress, ENT - ear nose and throat, PRISM - Paediatric RISk of Mortality score.</p

The influence of atropine of the change in heart rate during intubation of the two age sub-groups.

<p>The influence of atropine of the change in heart rate during intubation of the two age sub-groups.</p

Multivariable analysis of the change in heart rate during intubation following fall in peripheral oxygen saturation (SpO₂) and after the use of atropine (corrected by the propensity score [PS]). Neonates are ≤28 days and older children >28 days and less than 8 years.

<p>Multivariable analysis of the change in heart rate during intubation following fall in peripheral oxygen saturation (SpO₂) and after the use of atropine (corrected by the propensity score [PS]). Neonates are ≤28 days and older children >28 days and less than 8 years.</p

Flow-chart of inclusions, non-inclusions and exclusions. Neonates are ≤28 days and older children >28 days and less than 8 years.

<p>*ICT - Intensive Care Transport team positioned antenatally for premature births.</p

The change in heart rate related to a change in peripheral oxygen saturation (SpO₂) during intubation.

<p>The change in heart rate related to a change in peripheral oxygen saturation (SpO₂) during intubation.</p