7 research outputs found
Report from the Annual Conference of the British Society of Echocardiography, November 2016, Queen Elizabeth II Conference Centre, London.
Peer reviewedPublisher PD
Semi-active control of magnetorheological dampers for automotive suspension systems
EThOS - Electronic Theses Online ServiceGBUnited Kingdo
Right ventricular function and region-specific adaptation in athletes engaged in high-dynamic sports: A meta-analysis
Background
Structural remodeling of the right ventricle (RV) is widely documented in athletes. However, functional
adaptation, including RV pressure generation and systolic free-wall longitudinal mechanics, remains
equivocal. This meta-analysis compared RV pressure and function in athletes and controls.
Methods
A systematic review of online databases was conducted up to June 4, 2020. Meta-analyses were
performed on RV systolic pressures (RVSP), at rest and during exercise, tricuspid annular plane systolic
displacement (TAPSE), myocardial velocity (Sâ), and global and regional longitudinal strain. Bias was
assessed using Eggerâs regression for asymmetry. Data were analyzed using random-effects models
with weighted mean difference (WMD) and 95% confidence interval (95%CI).
Results
Fifty-three studies were eligible for inclusion. RVSP was obtained from 21 studies at rest
(n=1043:1651; controls:athletes) and 8 studies during exercise (n=240:495) and was significantly
greater in athletes at rest (WMD: 2.9mmHg, CI: 1.3-to-4.5mmHg; P=0.0005) and during exercise (11.0,
6.5-to-15.6 mmHg; P<0.0001) vs. controls. Resting TAPSE (P<0.0001) and Sâ (P=0.001) were greater
in athletes. In contrast, athletes had similar RV free-wall longitudinal strain (17 studies; n=450:605),
compared to controls, but showed greater longitudinal apical strain (16 studies; n=455:669; 0.9%, 0.1-
to-1.8%;P=0.03) and lower basal strain (-2.5%, -1.4-to -3.5%;P<0.0001).
Conclusions
Functional RV adaptation, characterized by increased tricuspid annular displacement and velocity and
a greater base-to-apex strain gradient, is a normal feature of the athleteâs heart, together with a slightly
elevated RVSP. These findings contribute to our understanding of RV in athletes and highlight the
importance of considering RV function in combination with structure in the clinical interpretation of
the athleteâs heart