72 research outputs found

    The hierarchical control and protection of power systems

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    Editing and reading early modern mathematical texts in the digital age

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    The advent of digital technology has brought a world of new possibilities for editors of historical texts. Though much has been written about conventions for digital editing, relatively little attention has been paid to the particular question of how best to deal with texts with heavily mathematical content. This essay outlines some ways of encoding mathematics in digital form, and then discusses three recent digital editions of collections of early modern mathematical manuscripts

    Computer simulations of the growth of synthetic peptide fibres

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    Abstract. We present a coarse-grained computer model designed to study the growth of fibres in a synthetic self-assembling peptide system. The system consists of two 28 residue α-helical sequences, denoted AB and CD, in which the interactions between the half peptides, A, B, C and D, may be tuned individually to promote different types of growth behaviour. In the model, AB and CD are represented by double ended rods, with interaction sites distributed along their lengths. Monte Carlo simulations are performed to follow fibre growth. It is found that lateral and longitudinal growth of the fibre are governed by different mechanisms -the former is diffusion limited with a very small activation energy for the addition of units, whereas the latter occurs via a process of secondary nucleation at the fibre ends. As a result, longitudinal growth generally proceeds more slowly than lateral growth. Furthermore, it is shown that the aspect ratio of the growing fibre may be controlled by adjusting the temperature and the relative strengths of the interactions. The predictions of the model are discussed in the context of published data from real peptide systems
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