Effect of International Federation of Gynecology and Obstetrics- the Federation of Obstetric and Gynecological Societies of India Postpartum Intra Uterine Contraceptive Device initiative, India on postpartum contraceptive choices- last year and post-project one-year review in a rural medical college

Background: The FIGO-FOGSI launched an initiative in 2015 to expand the use of PPIUCD in six centers in phase 1, including our institution. This study aimed at the evaluating the effect of this program on the postpartum contraceptive choices during the last year of the project and one year thereafter.Methods: This was a clinical study conducted in the Department of Obstetrics and Gynecology, College of Medicine and J. N. M. Hospital, Kalyani, West Bengal, India from 1 January 2018 to 31 December 2019. All antenatal women were counseled about the various methods available for postpartum contraception. Data was collected on a monthly basis and results were analyzed.Results: There was a marked reduction of the acceptance rate of PPIUCD after the withdrawal of the program, with mild variation of the user percentage of most other methods.Conclusions: Further initiation and continuation of this FIGO-FOGSI project may definitely improve the scenario of acceptance of postpartum family-planning methods in this institution. However, in the existing situation, the capacity of available human resources should be built towards achieving this, to sustain the same impact as while on the FOGSI-FIGO project

Hydrogen bonded supramolecular architecture of a copper(II)-citrate coordination building block: Synthesis and crystal structure with theoretical insight

A tricarboxylate supported binuclear metal organic hybrids of Cu(II), [Cu2(µ-cit)(phen)4]·9H2O (1) has been synthesized using well known pyridyl based N,N′ linker, 1,10-phenanthroline and has been structurally characterized. The use of the flexible hydroxyl tricarboxylate, citrate, in designing such framework has created a marked diversity in the topology. The structural and topological diversity has been analyzed from the single crystal X-ray structure. Here, in an unit, each of the two Cu(II) centres are chelated by two phenanthrolineligands and citrate (cit4-) serves the role of a bridging ligand. Furthermore, the carboxylate moiety/hydroxyl oxygen sites of citrate and the aromatic chelating ligands promote the supramolecular recognition through hydrogen bonding and other non-covalent interactions (like π-π interaction) and thereby results in higher dimensional architecture.Along with this, there are water molecules as water of crystallization. The oxygen atoms of the carboxylate moiety involve in both inter and intra-molecular hydrogen bonding with the hydrogen atoms of the water molecules resulting in a hydrogen bonded helical supramolecular solid. Theoretical study is performed to analyze the structure and the role of non-covalent interactions through DFT based calculations and Hirshfeld surface analysis

An ensemble prediction approach to weekly Dengue cases forecasting based on climatic and terrain conditions

Introduction: Dengue fever has been one of the most concerning endemic diseases of recent times. Every year, 50-100 million people get infected by the dengue virus across the world. Historically, it has been most prevalent in Southeast Asia and the Pacific Islands. In recent years, frequent dengue epidemics have started occurring in Latin America as well. This study focused on assessing the impact of different short and long-term lagged climatic predictors on dengue cases. Additionally, it assessed the impact of building an ensemble model using multiple time series and regression models, in improving prediction accuracy. Materials and Methods: Experimental data were based on two Latin American cities, viz. San Juan (Puerto Rico) and Iquitos (Peru). Due to weather and geographic differences, San Juan recorded higher dengue incidences than Iquitos. Using lagged cross-correlations, this study confirmed the impact of temperature and vegetation on the number of dengue cases for both cities, though in varied degrees and time lags. An ensemble of multiple predictive models using an elaborate set of derived predictors was built and validated. Results: The proposed ensemble prediction achieved a mean absolute error of 21.55, 4.26 points lower than the 25.81 obtained by a standard negative binomial model. Changes in climatic conditions and urbanization were found to be strong predictors as established empirically in other researches. Some of the predictors were new and informative, which have not been explored in any other relevant studies yet. Discussion and Conclusions: Two original contributions were made in this research. Firstly, a focused and extensive feature engineering aligned with the mosquito lifecycle. Secondly, a novel covariate pattern-matching based prediction approach using past time series trend of the predictor variables. Increased accuracy of the proposed model over the benchmark model proved the appropriateness of the analytical approach for similar epidemic prediction research

Hydrogen bonded supramolecular architecture of a copper(II)-citrate coordination building block: Synthesis and crystal structure with theoretical insight

469-476A tricarboxylate supported binuclear metal organic hybrid of Cu(II), [Cu2(µ-cit)(phen)4]·9H2O (1) has been synthesized using the well known pyridyl based N,N′ linker, 1,10-phenanthroline and structurally characterized. The use of the flexible hydroxyl tricarboxylate citrate, in designing such a framework has created a marked diversity in the topology. The structural and topological diversity has been analyzed from the single crystal X-ray structure. Here, in a unit, each of the two Cu(II) centres is chelated by two phenanthroline ligands and citrate (cit4–) serves the role of a bridging ligand. Furthermore, the carboxylate moiety/hydroxyl oxygen sites of citrate and the aromatic chelating ligands promote supramolecular recognition through hydrogen bonding and other non-covalent interactions (like π-π interaction) and water of crystallization, thereby resulting in a higher dimensional architecture. The oxygen atoms of the carboxylate moiety involve in both inter and intra-molecular hydrogen bonding with the water molecules resulting in a hydrogen bonded helical supramolecular solid. Theoretical study is performed to analyze the structure and the role of non-covalent interactions through DFT based calculations and Hirshfeld surface analysis