3 research outputs found
The First Organocatalytic Addition of 2-Trimethylsilyloxyfuran to Carbonyl Compounds: Hydrogen-Bond Catalysis in g-Butenolides Synthesis
No full textThis letter describes the first example of diastereoselective ‘organocatalyzed’ synthesis of the butenolide products
substituted at the c-position by a chain bearing hydroxyl groups. The urea-derivative 4 has proved to be an efficient catalyst
for the addition of the commercial TMSOF to carbonyl compounds under solvent-free conditions. The reaction conditions and
generality of the procedure have been examined
