7 research outputs found

    Data Mining in Promoting Flight Safety

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    The incredible rapid development to huge volumes of air travel, mainly because of jet airliners that appeared to the sky in the 1950s, created the need for systematic research for aviation safety and collecting data about air traffic. The structured data can be analysed easily using queries from databases and running theseresults through graphic tools. However, in analysing narratives that often give more accurate information about the case, mining tools are needed. The analysis of textual data with computers has not been possible until data mining tools have been developed. Their use, at least among aviation, is still at a moderate level. The research aims at discovering lethal trends in the flight safety reports. The narratives of 1,200 flight safety reports from years 1994 – 1996 in Finnish were processed with three text mining tools. One of them was totally language independent, the other had a specific configuration for Finnish and the third originally created for English, but encouraging results had been achieved with Spanish and that is why a Finnish test was undertaken, too. The global rate of accidents is stabilising and the situation can now be regarded as satisfactory, but because of the growth in air traffic, the absolute number of fatal accidents per year might increase, if the flight safety will not be improved. The collection of data and reporting systems have reached their top level. The focal point in increasing the flight safety is analysis. The air traffic has generally been forecasted to grow 5 – 6 per cent annually over the next two decades. During this period, the global air travel will probably double also with relatively conservative expectations of economic growth. This development makes the airline management confront growing pressure due to increasing competition, signify cant rise in fuel prices and the need to reduce the incident rate due to expected growth in air traffic volumes. All this emphasises the urgent need for new tools and methods. All systems provided encouraging results, as well as proved challenges still to be won. Flight safety can be improved through the development and utilisation of sophisticated analysis tools and methods, like data mining, using its results supporting the decision process of the executives.Lentoliikenne kasvoi huomattavasti 1950-luvulla pääasiassa suihkumatkustajakoneiden myötä, mikä aiheutti poikkeamatietojen järjestelmällisen keräämisen ja tutkimuksen tarpeen. Määrämuotoinen tieto voidaan helposti analysoida tietokantakyselyillä esittäen tulokset käyttäen graafisia työkaluja, mutta tekstianalyysiin, jonka avulla tapauksista saadaan usein tarkempia tietoja, tarvitaan louhintatyökaluja. Tekstimuotoisen tiedon automaattinen analysointi ei ole ollut mahdollista ennen louhintatyökalujen kehittämistä. Silti niiden käyttö, ainakin ilmailun piirissä, on edelleen vähäistä. Tutkimuksen tarkoituksena oli havaita vaarallisia kehityskulkuja lentoturvallisuusraporteissa. 1 200 lentoturvallisuusraportin selostusosiot vuosilta 1994 –1996 käsiteltiin kolmella tekstinlouhintatyökalulla. Yksi näistä oli täysin kieliriippumaton, toisessa oli lisäosa, jossa oli mahdollisuus käsitellä suomen kieltä ja kolmas oli rakennettu alun perin ainoastaan englanninkielisen tekstin louhintaan, mutta espanjan kielellä saavutettujen rohkaisevien tulosten pohjalta päätettiin kokeilla myös suomenkielistä tekstiä. Lento-onnettomuuksien määrä liikenteeseen nähden on vakiintumassa maailmanlaajuisesti katsottuna ja turvallisuustaso voidaan katsoa tyydyttäväksi. Kuitenkin liikenteen kasvaessa myös onnettomuuksien määrä lisääntyy vuosittain, mikäli lentoturvallisuutta ei kyetä parantamaan. Turvallisuustiedon kerääminen ja raportointijärjestelmät ovat jo saavuttaneet huippunsa. Analysoinnin parantaminen on avain lentoturvallisuuden parantamiseen. Lentoliikenteen on ennustettu kasvavan 5 – 6 prosenttia vuodessa seuraavien kahden vuosikymmenen ajan. Samana aikana lentoliikenne saattaa kaksinkertaistua jopa vaatimattomimpien talouskasvuennusteiden mukaan. Tällainen kehitys asettaa lentoliikenteen päättäjille yhä kasvavia paineita kiristyvän kilpailun, polttoaineiden hinnannousun ja liikenteen kasvun aiheuttaman onnettomuuksien määrän vähentämiseksi. Tämä korostaa uusien menetelmien ja työkalujen kiireellistä tarvetta. Kaikilla louhintajärjestelmillä saatiin rohkaisevia tuloksia mutta ne nostivat samalla esille haasteita, jotka tulisi vielä voittaa. Lentoturvallisuutta voidaan vielä parantaa käyttämällä tässä esille tuotuja analyysimenetelmiä ja –työkaluja kuten tiedonlouhintaa ja soveltamalla näin saatuja tuloksia johdon päätöksenteon tukena.Siirretty Doriast

    Data Mining Challenges in the Management of Aviation Safety

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    Part 2: Digital Society International audience This paper introduces aviation safety data analysis as an important application area for data mining. Safety is a key strategic management concern for safety-critical industries and management needs new, more efficient tools and methods for more effective management routines. The aviation field is confronted with increasing challenges to provide safe and fluent services. Air travel has grown steadily during the last decades with a direct impact on the air traffic control. At the same time, the competition has become tougher because of increasing fuel prices and growing demand for air travel. Document type: Part of book or chapter of boo

    Proceedings of the Seventh International Conference on Well-Being in the Information Society: Fighting Inequalities (WIS 2018)

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    Effective methods are needed to identify and manage risks in healthcare to improve patient safety and hence the reputation of health care. Analysing safety related records and learning from ‘touch and go’ situations as well as accidents is one possible way of preventing hazardous conditions from occurring in healthcare, both public and private. The eventuality of an incident or an accident may markedly be reduced if the risks connected to it are efficiently diagnosed. This paper explores how a data mining technique can be applied to healthcare in order to discover harm causing factors in vast amounts of patient safety records.</p

    Clinical experience and cost evaluation of magnetic resonance imaging -only workflow in radiation therapy planning of prostate cancer

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    AbstractBackground and purposeIn radiation therapy (RT), significant improvements have been made recently particularly in the practices of planning imaging. This study aimed to conduct a cost evaluation between magnetic resonance imaging (MRI) -only and combined computed tomography (CT) and MRI workflows.Materials and methodsThe time-driven activity-based costing (TDABC) model was used to conduct a cost evaluation between the two workflows in those steps, where cost differences were expected. Costs were divided into capital costs and operational costs. The former consisted of fixed, one-time expenses, e.g. the purchase of a scanner, whereas the latter were partially based on the amount of activity consumed i.e. time required for image acquisition, image registration and structure contouring.ResultsIn a review over a period of 10 years for 300 annual prostate cancer patients, the total cost of the workflow steps included in the study for an individual patient applying the MRI-only workflow was 903 € (100%), comprised of 537 € (59%) capital costs and 366 € (41%) operational costs. The corresponding total cost for an individual patient applying the CT + MRI workflow was 922 € (100%), comprised of 197 € (21%) capital costs and 726 € (79%) operational costs. In 10 years for 3000 patients, a total saving of 58,544 € (2%) was achieved with the MRI-only workflow compared with the dual imaging workflow.ConclusionsMRI-only workflow is a feasible and economic way to perform clinical RT for localized prostate cancer, in particular for medium- and large-sized departments treating a sufficient number of patients.</p

    Tiedonkulun vaikutus SOTE-palvelujen maineeseen

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    Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer

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    Prostate cancer is the third most common cause of male cancer death in developed countries, and one of the most comprehensively characterized human cancers. Roughly 60% of prostate cancers harbor gene fusions that juxtapose ETS-family transcription factors with androgen regulated promoters. A second subtype, characterized by SPINK1 overexpression, accounts for 15% of prostate cancers. Here we report the discovery of a new prostate cancer subtype characterized by rearrangements juxtaposing the SMAD inhibitor SKIL with androgen regulated promoters, leading to increased SKIL expression. SKIL fusions were found in 6 of 540 (1.1%) prostate cancers and 1 of 27 (3.7%) cell lines and xenografts. 6 of 7 SKIL-positive cancers were negative for ETS overexpression, suggesting mutual exclusivity with ETS fusions. SKIL knockdown led to growth arrest in PC-3 and LNCaP cell line models of prostate cancer, and its overexpression led to increased invasiveness in RWPE-1 cells. The role of SKIL as a prostate cancer oncogene lends support to recent studies on the role of TGF-β signaling as a rate-limiting step in prostate cancer progression. Our findings highlight SKIL as an oncogene and potential therapeutic target in 1-2% of prostate cancers, amounting to an estimated 10,000 cancer diagnoses per year worldwide.This article has supplementary files, which can be found here:http://dx.doi.org/10.18632/oncotarget.335
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