2,732 research outputs found

    Single Sampling Plans for Variables Indexed by AQL and AOQL with Measurement Error

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    Single sampling plans are investigated for variables indexed by acceptable quality level (AQL) and average outgoing quality limit (AOQL) under measurement error. Procedures and tables are provided for selection of single sampling plans for variables for given AQL and AOQL when rejected lots are 100% inspected for replacement of a nonconforming unit. For a particular sampling plan in operation for an observed measurement, a method for determining true operating characteristic (OC) functions and average outgoing quality (AOQ) is described for various error sizes

    Observation of Change in Colour of Combustible Cartridge Cases on Ageing-A Qualitative Tool

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    The stability of combustible cartridge cases (CCCs) which are extensively used in the high calibre tank gun ammunition is one of the major requirements for their safe handling and storage. The results of stability tests by heating of CCC samples at elevated temperatures and observations for change in colour of the CCC samples have been discussed. It has been observed that there are drastic changes in the colour of the CCC samples. The original pale yellow colour of the uncoated internal surface was changed to dark green. Similarly, original yellowish-brown colour of external surface coated with shellac varnish was changed to dark greenish-brown

    North American Symposium on Laser-Induced Breakdown Spectroscopy: Introduction to the feature issue

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    This feature issue highlights the topics presented at the 2009 North American Symposium on Laser-Induced Breakdown Spectroscopy, in New Orleans, Louisiana, held 13-15 July 2009. © 2010 Optical Society of America

    Theoretical search for Chevrel phase based thermoelectric materials

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    We investigate the thermoelectric properties of some semiconducting Chevrel phases. Band structure calculations are used to compute thermopowers and to estimate of the effects of alloying and disorder on carrier mobility. Alloying on the Mo site with transition metals like Re, Ru or Tc to reach a semiconducting composition causes large changes in the electronic structure at the Fermi level. Such alloys are expected to have low carrier mobilities. Filling with transition metals was also found to be incompatible with high thermoelectric performance based on the calculated electronic structures. Filling with Zn, Cu, and especially with Li was found to be favorable. The calculated electronic structures of these filled Chevrel phases are consistent with low scattering of carriers by defects associated with the filling. We expect good mobility and high thermopower in materials with the composition close to (Li,Cu)4_4Mo6_6Se8_8, particularly when Li-rich, and recommend this system for experimental investigation.Comment: 4 two-column pages, 4 embedded ps figure

    Elastic Scattering of 200 MeV Polarized Protons from 9-Be and 16-O

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    This work was supported by the National Science Foundation Grant NSF PHY 78-22774 A02 & A03 and by Indiana Universit

    A novel mutation in GJA8 associated with autosomal dominant congenital cataract in a family of Indian origin

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    Purpose To identify the underlying genetic defect in a four-generation family of Chinese origin with autosomal dominant congenital cataract-microcornea syndrome (CCMC). Methods All individuals in the study underwent a full clinical examination and the details of history were collected . Genomic DNA extracted from peripheral blood was amplified by polymerase chain reaction (PCR) method and the exons of all candidate genes were sequenced. Results Direct sequencing of the encoding regions of the candidate genes revealed a heterozygous mutation c.592C→T in exon 2 of the gap junction protein, alpha 8 (GJA8) gene. This mutation was responsible for the familial disorder through the substitution of a highly conserved arginine to tryptophan at codon 198 (p.R198W). This change co-segregated with all affected members of the family, but was not detected either in the non-carrier relatives or in the 100 normal controls. Conclusions This report is the first to relate p.R198W mutation in GJA8 with CCMC. The result expands the mutation spectrum of GJA8 in associated with congenital cataract and microcornea, and implies that this gene has direct involvement with the development of the lens as well as the other anterior segment of the eye

    A novel fan-shaped cataract-microcornea syndrome caused by a mutation of CRYAA in an Indian family

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    PURPOSE: The molecular characterization of an Indian family having 10 members in four generations affected with a unique fan-shaped cataract-microcornea syndrome. METHODS: Detailed family history and clinical data were recorded. A genome-wide screening by two-point linkage analysis using more than 400 microsatellite markers in combination with multipoint lod score and haplotype analysis was carried out. Mutation screening was performed in the candidate gene by bi-directional sequencing of amplified products. RESULTS: The cataract-microcornea locus in this family was mapped to a 23.5 cM region on chromosome 21q22.3. Direct sequencing of the candidate gene CRYAA revealed a heterozygous C>T transition resulting in the substitution of the highly conserved arginine at position 116 by cysteine (R116C). CONCLUSIONS: This study provides the report of mapping a locus for syndromal cataract (cataract-microcornea syndrome) on 21q22.3. The mutation observed in CRYAA in the present family highlights the phenotypic heterogeneity of the disorder in relation to the genotype, as an identical mutation has previously been reported in an American family with a different type of cataract. The "fan-shaped cataract" observed in the present family has not been reported before

    Integrated electrical and mechanical modelling of integrated-full-electric-propulsion systems

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    Integrated Full Electric Propulsion (IFEP) systems are the subject of much interest at present. Current research is focused on analysing and improving aspects of subsystem and system performance. However, there is a great need to look more widely at the `multi-physics' problem of characterising the dynamic interactions between the electrical and mechanical systems. This paper will discuss the changing nature of modelling and simulation to aid research into IFEP systems, outlining the alternative angle taken by the Advanced Marine Electrical Propulsion Systems (AMEPS) project to characterise and investigate electrical-mechanical system interactions. The paper will describe this approach and highlight the unique challenges associated with the problem, discussing the suitable methods that will be adopted to address these challenges. Finally, an overview of the present and future research opportunities facilitated via the AMEPS project will be presented

    Sutural cataract associated with a mutation in the ferritin light chain gene (FTL) in a family of Indian origin

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    PURPOSE: The molecular characterization of 27 members of an Indian family, with 13 members in four generations, affected with Y-sutural congenital cataract. METHODS: Detailed family history and clinical data were collected. A genome-wide scan by two-point linkage analysis using more than 400 microsatellite markers in combination with multipoint lod score and haplotype analysis was performed. Mutation screening was carried out in the candidate gene by bi-directional sequencing of amplified products. RESULTS: A maximum two-point lod score of 6.37 at theta=0.00 was obtained with marker D19S879. Haplotype analysis placed the cataract locus to a 5.0 cM region between D19S902 and D19S867, in close proximity to the L-ferritin light chain gene (FTL) on chromosome 19q13.3. Hematological tests in two affected individuals showed very high levels of serum ferritin without iron overload leading to the diagnosis of hyperferritinemia-cataract syndrome. Mutation screening in FTL identified a G>A change at position 32 (c.-168G>A) in a highly conserved 3 nucleotide motif that forms a loop structure in the iron responsive element (IRE) in the 5'-untranslated region (5'-UTR). This nucleotide alteration was neither seen in any unaffected member of the family nor found in 50 unrelated control subjects. CONCLUSIONS: The present study is the first report of a Y-sutural congenital cataract mapping to 19q13.3. The mutation observed in FTL in this family highlights the phenotypic heterogeneity of the disorder in relation to the genotype as the identical mutation (32 G>A) has previously been reported in two Italian families with entirely different phenotypes. It is also the first report of hereditary hyperferritinemia-cataract syndrome in a family of Indian origin

    Systematic 1/S study of the 2D Hubbard model at half-filling

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    The 2D Hubbard model is extended by placing 2S orbitals at each lattice site and studied in a systematic 1/S expansion. The 1/S results for the magnetic susceptibility and the spectra of spin-wave excitations at half-filling are consistent with the large S calculations for the Heisenberg antiferromagnet. The 1/S corrections to the fermionic spectrum lift the degeneracy along the edge of the magnetic Brillouin zone yielding minima at (+- pi/2, +- pi/2). Relation to previous papers on the subject is discussed.Comment: 18 pages, emTex version 3.
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