Principal Component Analysis of our Peruvian samples of gastric cancer cases, their controls, and Native Americans in the context of HapMap-III European, African, and Mexican individuals, and distribution of Native American ancestry in cases and controls

<p>(<b>box</b>)<b>.</b> Each individual was genotyped for 103 ancestry informative markers validated by Yaeger et al. (2008). We represent the first (horizontal) and second (vertical) principal components, which capture the 35.3% and 7.7% of total variance, respectively. HapMap individuals: YRI: Yoruba from Nigeria, LWK: Luhya from Kenya, ASW: African American from Southwest USA, MKK: Maasai from Kenya, CEU: Utah residents with European ancestry, TSI: Toscani from Italy, MEX: Mexican ancestry resident in Los Angeles. Peruvian Native Americans: Shimaa (SHI) and Ashaninkas (ASH) from the Matsiguenga ethnic group, and individuals from Puno in the Andes (PU). The box within the figure shows the density plot and means (vertical lines) of Native American ancestry in the gastric cancer cases (yellow) and controls (brown).</p

Socioeconomic, nutritional, and digestive-symptom-related variables and their association with gastric cancer and Native American ancestry.

<p>Association tests reported in the table are: (^a) OR: Odd ratio, (^b): χ² test, (^c): G-test, (^d): logistic regression, (^e): Mann-Withney, (^f): Kruskal-Wallis, (^g): Spearman rank order correlation.</p

Copy Number Data from Population genetics of immune-related multilocus copy number variation in Native Americans

Individual copy number dat

Tables S8 and S9 from Population genetics of immune-related multilocus copy number variation in Native Americans

Diploid copy number distributions of DEFB and FCGR3B loci for worldwide populations (Human Genome Diversity Project panel) and allele frequencies and fCNV inferred using CoNVEM (A) and CNVice (B)

Tables S11 and S13 from Population genetics of immune-related multilocus copy number variation in Native Americans

Genotyping of 53 trios and Reference samples with known copy numbers from the European Collection of Cell Cultures

Supplementary Material from Population genetics of immune-related multilocus copy number variation in Native Americans

Supplementary material, including text, figures and tables

Tables S3 to S7 from Population genetics of immune-related multilocus copy number variation in Native Americans

Diplotype distributions for all loci and inferred allelic frequency in populations and subpopulations with CoNVEM (A) and CNVice (B)