Екологічний стан агроландшафтів території межиріччя Західного Бугу та Прип’ять

The results of the evaluation of the ecological status of the territory of agricultural landscapes between the rivers Western Bug and Pripyat are given in view the existing ecological-reclamation monitoring system. It is highlighted the need to control water flow and water supplies to prevent negative consequences from the possible anthropogenic impact on the underground hydrosphere of the region.Наведено результати оцінювання екологічного стану агроландшафтів території межиріччя Західного Бугу та Прип’яті з урахуванням існуючої системи еколого-меліоративного моніторингу. Відмічено необхідність контролю водотоків та водозапасів для уникнення негативних наслідків з боку можливого антропогенного втручання в підземну гідросферу регіон

HYSTYOCYTOSIS X: VERIFICATION OF DIAGNOSIS

A clinical case of histiocytosis X, rarely found in the practice of a dermatovenereologist, is described, the pathognomonic clinical symptoms of this dermatosis, including skin lesions, that occur in 50 to 80 % of cases of all forms are displayed. The modern classification of histiocytosis, pathogenetic mechanisms of development and clinic of histiocytosis Х are given. Particular attention is paid to diagnostic methods, the necessity of interaction of narrow specialists (dermatovenerologists, hematologists, oncologists, pulmonologists) is underlined

On the water-bag model of dispersionless KP hierarchy

We investigate the bi-Hamiltonian structure of the waterbag model of dKP for two component case. One can establish the third-order and first-order Hamiltonian operator associated with the waterbag model. Also, the dispersive corrections are discussed.Comment: 19 page

Performance for proton anisotropic flow measurement of the CBM experiment at FAIR

The Compressed Baryonic Matter experiment (CBM) performance for proton anisotropic flow measurements is studied with Monte-Carlo simulations using collisions of gold ions at lab momentum of 12A GeV/c employing DCM-QGSM-SMM heavy-ion event generator. Realistic procedures are used for centrality estimation with the number of registered tracks and particle identification with information from Time-Of-Flight detector. Variation of directed flow estimates depending on various combinations of PSD modules is used to evaluate possible systematic biases due to collision symmetry plane estimation

LED-technologies for bright light therapy

The significance of the LED-based medical equipment design is caused by the need to make up for the sunshine shortfall in many areas of Russia (Siberia, the Far East, the Extreme North) that will allow reducing dramatically the risk of seasonal affective disorders. The sunshine is the essential synchronizer of the human biological rhythms, the abnormality of which plays an important role in the seasonal affective disorder nature. The study allows proving the object database development able to meet the human demand for a comfortable and high-quality placemaking as well as the health potential recoverability

Синтез новых фотоотверждаемых фосфорсодержащих олигоэфирметакрилатов со спейсером в структуре

Objectives. To synthesize phosphorus-containing oligoestermethacrylates spatially separated by spacers of aliphatic or aromatic structure and evaluate their effect on photocuring kinetics.Methods. For determining the qualitative and quantitative composition of the synthesized compounds, the following methods were used: thin layer chromatography; chromatographic and mass spectrometry; infrared spectroscopy; 1H, 13C, 31P nuclear magnetic resonance spectroscopy; differential scanning calorimetry. The dielectric loss tangent was determined on a specially designed optical cell with an ultraviolet (UV) light source to an immittance meter. Elemental analysis was performed on an energy dispersive X-ray fluorescence spectrometer.Results. Spatially separated oligoestermethacrylates based on phosphorus trichloride containing aliphatic or aromatic spacers in the structure were synthesized. During the interaction of glycidyl methacrylate with phosphorus trichloride in the mass of the latter, reaction products were shown to be formed both according to the Krasusky rule from the side of the α-carbon atom, as well as against this rule with the formation of isomeric products. Obtaining these compounds in bulk is possible only in the presence of a homopolymerization inhibitor. The influence of the spacer structure on the curing rate of oligoestermethacrylates under the action of UV radiation has been established. It has been shown that the introduction of a spacer into the oligomer structure is accompanied by an increase in the induction period by a factor of 39 compared to a sample without a spacer.Conclusions. The results obtained indicate the possibility of obtaining new oligoestermethacrylates with aliphatic and aromatic spacers in the structure. The influence of the structure of the spacer on the kinetics of photocuring is determined.Цели. Синтез фосфорсодержащих олигоэфирметакрилатов, пространственно-разделенных спейсерами алифатического или ароматического строения, и оценка их влияния на кинетику фотоотверждения.Методы. Для определения качественного и количественного состава синтезированных соединений использованы: тонкослойная хроматография; хромато-масс-спектрометрия; инфракрасная спектроскопия; 1H, 13C, 31P спектроскопия ядерного магнитного резонанса; дифференциальная сканирующая калориметрия. Тангенс диэлектрических потерь определяли на специально разработанной оптической ячейке с УФ-источником света к измерителю иммитанса. Элементный анализ проводили на энергодисперсионном рентгенофлуоресцентном спектрометре.Результаты. Синтезированы пространственно разделенные олигоэфирметакрилаты на основе трихлорида фосфора, содержащие в структуре алифатический или ароматический спейсеры. Установлено, что при взаимодействии глицидилметакрилата с трихлоридом фосфора в массе последнего, образуются продукты реакции как по правилу Красуского со стороны α-углеродного атома, так и против правила с образованием изомерных продуктов. Получение данных соединений в массе возможно только в присутствии ингибитора гомополимеризации. Установлено влияние структуры спейсера на скорость отверждения олигоэфирметакрилатов под действием УФ-излучения. Показано, что введение спейсера в структуру олигомера сопровождается увеличением индукционного периода в 39 раз по сравнению с образцом, не содержащим спейсера.Выводы. Достигнутые результаты свидетельствуют о возможности получения новых олигоэфирметакрилатов со спейсерами алифатического и ароматического строения в структуре. Установлено влияние строения спейсера на кинетику фотоотверждения

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology

Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is unknown. To study this issue, here we develop a model of human central metabolism that incorporates a solvent capacity constraint of metabolic enzymes and mitochondria, accounting for their occupied volume densities, while assuming glucose and/or fatty acid utilization. The model demonstrates that activation of aerobic glycolysis is favored above a threshold metabolic rate in both rapidly proliferating cells and heavily contracting muscles, because it provides higher ATP yield per volume density than mitochondrial oxidative phosphorylation. In the case of muscle physiology, the model also predicts that before the lactate switch, fatty acid oxidation increases, reaches a maximum, and then decreases to zero with concomitant increase in glucose utilization, in agreement with the empirical evidence. These results are further corroborated by a larger scale model, including biosynthesis of major cell biomass components. The larger scale model also predicts that in proliferating cells the lactate switch is accompanied by activation of glutaminolysis, another distinctive feature of the Warburg effect. In conclusion, intracellular molecular crowding is a fundamental constraint for cell metabolism in both rapidly proliferating- and non-proliferating cells with high metabolic demand. Addition of this constraint to metabolic flux balance models can explain several observations of mammalian cell metabolism under steady state conditions

LED-technologies for bright light therapy

The significance of the LED-based medical equipment design is caused by the need to make up for the sunshine shortfall in many areas of Russia (Siberia, the Far East, the Extreme North) that will allow reducing dramatically the risk of seasonal affective disorders. The sunshine is the essential synchronizer of the human biological rhythms, the abnormality of which plays an important role in the seasonal affective disorder nature. The study allows proving the object database development able to meet the human demand for a comfortable and high-quality placemaking as well as the health potential recoverability

The history of degenerate (bipartite) extremal graph problems

This paper is a survey on Extremal Graph Theory, primarily focusing on the case when one of the excluded graphs is bipartite. On one hand we give an introduction to this field and also describe many important results, methods, problems, and constructions.Comment: 97 pages, 11 figures, many problems. This is the preliminary version of our survey presented in Erdos 100. In this version 2 only a citation was complete

Representations of solutions of the wave equation based on relativistic wavelets

A representation of solutions of the wave equation with two spatial coordinates in terms of localized elementary ones is presented. Elementary solutions are constructed from four solutions with the help of transformations of the affine Poincar\'e group, i.e., with the help of translations, dilations in space and time and Lorentz transformations. The representation can be interpreted in terms of the initial-boundary value problem for the wave equation in a half-plane. It gives the solution as an integral representation of two types of solutions: propagating localized solutions running away from the boundary under different angles and packet-like surface waves running along the boundary and exponentially decreasing away from the boundary. Properties of elementary solutions are discussed. A numerical investigation of coefficients of the decomposition is carried out. An example of the field created by sources moving along a line with different speeds is considered, and the dependence of coefficients on speeds of sources is discussed.Comment: submitted to J. Phys. A: Math. Theor., 20 pages, 6 figure