自発的ドック受診者群と企業健診受診者群の脳MRIにおけるT2高信号域個数の比較

he purpose of this study was to evaluate the difference in T2-elongated spots (T2ES) between self-referred and third party-referred subjects.The brain MRI studies of 814 healthy adults were assessed. The subjects were categorized into two groups. Group A included 312 self-referred subjects ranging in age from 49 to 65 years (mean age, 56.5 years). Group B included 502 third party-referred subjects same ranging in age (mean age, 54.3 years). All subjects were asked to complete an interview sheet dealing with current and past diseases. To compare the two groups, an ‘Age-related Grading System\u27 was created.Grade 4 was defined as including patients who had 10 to 14 more T2ESs than their age minus 49; 20.027771275620f Group B and 13.51111400240f Group A (P<0.05) were classified as Grade 4. Diabetes mellitus was present in 15.016010062550f Group A and 9.615734071165f Group B (P<0.05). Hyperlipidemia was present in 18.015710062563f Group A and 9.015035020146f Group B (P<0.01).Although diabetes mellitus and hyperlipidemia were more common in Group A, these diseases were considered to be well controlled. It would appear that the patients in Group A were more health conscious than those in Group B

Volumetric analyses.

<p>Volumetric analyses.</p

Twin intra-pair analyses.

<p>Twin intra-pair analyses.</p

Path diagram representing the structural equation model used to calculate A (additive genetics) and E (unique environmental) factors.

<p>Path diagram representing the structural equation model used to calculate A (additive genetics) and E (unique environmental) factors.</p

Plot of total brain volume and age.

<p>Plot of total brain volume and age.</p

Twin-twin correlation plot of total brain volume.

<p>Twin-twin correlation plot of total brain volume.</p

Structural equation modelling results.

<p>Structural equation modelling results.</p

Age, gender and MMSE (mini-mental state examination) of twin participants.

<p>Age, gender and MMSE (mini-mental state examination) of twin participants.</p

Accuracies for onset detection and classification of movement type.

<p>(A) The mean onset detection rate is shown from −2000 to 1000 ms with the standard deviation (<i>N</i> = 6). The N.D. (not detected) denotes the rate of trials in which no onset was detected from −2000 to 1000 ms (mean and standard deviation). Time 0 ms denotes target time to detect, which is the training time of the class decoder in training data sets. (B) Blue and red lines show the mean onset detection rates of contra-eSCP and ipsi-eSCP, respectively. The shaded area denotes the standard deviation (<i>N</i> = 6). (C) The green and red bars denote the average of the sensitivity and specificity of onset detection, respectively, and the error bars denote 95% confidence intervals. Asterisks show statistical significances (*<i>p</i> < 0.05, **<i>p</i> < 0.01, paired two-tailed Student’s <i>t</i>-test, <i>N</i> = 6) (D) The classification accuracies of movement type were compared among three types of features for decoding (**<i>p</i> < 0.01, paired two-tailed Student’s <i>t</i>-test, <i>N</i> = 6). The mean and 95% confidence interval are shown. Dotted line denotes chance level (50%).</p

SMF and eSCP at the timing of detected onset.

<p>(A) The SMF when movement onset was detected is color-coded at the location of the sensors. R, right; L, left. (B) The eSCP at the timing of the detection is color-coded on the normalized brain surface.</p