Additive Intraocular Pressure Lowering Effects of the Rho Kinase Inhibitor, Ripasudil in Glaucoma Patients Not Able to Obtain Adequate Control After Other Maximal Tolerated Medical Therapy

<p><b>Article full text</b></p> <p><br></p> <p>The full text of this article can be found here<b>. </b><a href="https://link.springer.com/article/10.1007/s12325-016-0389-3">https://link.springer.com/article/10.1007/s12325-016-0389-3</a></p><p></p> <p><br></p> <p><b>Provide enhanced content for this article</b></p> <p><br></p> <p>If you are an author of this publication and would like to provide additional enhanced content for your article then please contact <a href="http://www.medengine.com/Redeem/”mailto:[email protected]”"><b>[email protected]</b></a>.</p> <p><br></p> <p>The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.</p> <p><br></p> <p>Other enhanced features include, but are not limited to:</p> <p><br></p> <p>• Slide decks</p> <p>• Videos and animations</p> <p>• Audio abstracts</p> <p>• Audio slides</p

Macular sensitivity in each instrument.

<p>Macular sensitivity in each instrument.</p

OCT measurements and visual field sensitivity an accordance with the severity of glaucoma.

<p>OCT measurements and visual field sensitivity an accordance with the severity of glaucoma.</p

Test duration for each instrument.

<p>Test duration for each instrument.</p

Detection of the macular sensitivity in the right eye fundus image of a 47-year-old patient with primary open-angle glaucoma (POAG).

<p>Right eye fundus photo (A). Microperimetry results for the differential light thresholds that ranged from 0 to 36 dB with MAIA^TM (B) and from 0 to 34 dB with MP-3 (C) are shown.</p

Clinical characteristics of the study population.

<p>Clinical characteristics of the study population.</p

GCA thickness for the average, superior hemifield average, and inferior hemifield average.

<p>GCA thickness for the average, superior hemifield average, and inferior hemifield average.</p

Intraindividual variation of visual field measurements.

<p>Intraindividual variation of visual field measurements.</p

Comparison of the strength of structure-function relationship between visual field measurement instruments.

<p>Comparison of the strength of structure-function relationship between visual field measurement instruments.</p

Electrical Matching at Metal/Molecule Contacts for Efficient Heterogeneous Charge Transfer

In a metal/molecule hybrid system, unavoidable electrical mismatch exists between metal continuum states and frontier molecular orbitals. This causes energy loss in the electron conduction across the metal/molecule interface. For efficient use of energy in a metal/molecule hybrid system, it is necessary to control interfacial electronic structures. Here we demonstrate that electrical matching between a gold substrate and π-conjugated molecular wires can be obtained by using monatomic foreign metal interlayers, which can change the degree of d-π* back-donation at metal/anchor contacts. This interfacial control leads to energy level alignment between the Fermi level of the metal electrode and conduction molecular orbitals, resulting in resonant electron conduction in the metal/molecule hybrid system. When this method is applied to molecule-modified electrocatalysts, the heterogeneous electrochemical reaction rate is considerably improved with significant suppression of energy loss at the internal electron conduction