16 research outputs found
Attitudes of patients and physicians to insulin therapy in Japan: an analysis of the Global Attitude of Patients and Physicians in Insulin Therapy study
<p><b>Background</b>: The barriers to insulin therapy perceived by Japanese patients with diabetes and their physicians are unclear.</p> <p><b>Research design and methods</b>: We performed sub-analyses of the Global Attitude of Patients and Physicians in Insulin Therapy (GAPPā¢) study, which included 100 Japanese physicians (of 1250 participating physicians) and 150 Japanese patients (of 1530 patients) who participated in Internet surveys (physicians) or computer-assisted telephone surveys (patients) across eight countries in 2010. We compared the results of Japanese participants with those obtained for the other seven countries.</p> <p><b>Results</b>: Overall, 44% of the Japanese patients reported omission or non-adherence to insulin, a greater value than that reported in other countries. Japanese physicians reported that non-adherence to insulin was driven by their patientsā lifestyles. A greater proportion of patients had a history of hypoglycemia in Japan than in other countries. Most of the physicians (94%) and patients (84%) in Japan reported that the currently available insulin treatment regimens do not fit the diverse lifestyles of patients.</p> <p><b>Conclusions</b>: Many Japanese patients receiving insulin therapy omit or do not adhere to insulin, possibly because of fear of hypoglycemia, or for lifestyle reasons. Insulin regimens that reduce the risk of hypoglycemia without interfering with patientsā lifestyles are needed.</p
Long-term Effect of Color Record Method in Self-monitoring of Blood Glucose on Metabolic Parameters in Type 2 Diabetes: A 2-year Follow-up of the Color IMPACT Study
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MOESM2 of Efficacy and safety of canagliflozin in combination with insulin: a double-blind, randomized, placebo-controlled study in Japanese patients with type 2 diabetes mellitus
Additional file 2: Table S1. Time of onset of hypoglycemia (safety analysis set)
Social Orientation and Diabetes-Related Distress in Japanese and American Patients with Type 2 Diabetes
<div><p>Objective</p><p>Recent evidence in cultural and social psychology suggests Eastern cultures' emphasis on harmony and connection with others and Western cultures' emphasis on self-direction and autonomy. In Eastern society, relational harmony is closely linked to people's well-being. The impact of this cultural and social orientation on diabetes-related distress was investigated.</p><p>Research Design and Methods</p><p>Japanese and American patients with type 2 diabetes were surveyed by well-established questionnaire in Japan and in the United States, respectively. The association of personal values for interdependence, perceived emotional support, and the Problem Areas in Diabetes scale (PAID) were analyzed.</p><p>Results</p><p>A positive correlation between interdependence and PAID (<i>r</i>ā=ā0.18; <i>P</i>ā=ā0.025) and a negative correlation between perceived emotional support and PAID (<i>r</i>ā=āā 0.24; <i>P</i>ā=ā0.004) were observed after adjustments for other factors in Japanese data (<i>n</i>ā=ā149), but not in American data (<i>r</i>ā=ā0.00; <i>P</i>ā=ā0.990, <i>r</i>ā=ā0.02; <i>P</i>ā=ā0.917, respectively, <i>n</i>ā=ā50). In Japanese data, the three-factor structure of PAID (negative feelings about total life with diabetes, about living conditions with diabetes, and about treatment of diabetes) was identified, and interdependence showed significant positive correlations with the first and second factors and perceived emotional support showed significant negative correlations with all three factors of PAID.</p><p>Conclusions</p><p>These results suggest that personal values for interdependence may be linked to the level of diabetes-related distress and that the distress may be relieved by perception of emotional support, especially in an interdependent cultural context.</p></div
Factor loadings of the 20 items of PAID for the three extracted factors after promax rotation in Japanese.
<p>Factor loadings of the 20 items of PAID for the three extracted factors after promax rotation in Japanese.</p
Correlations between diabetes-related distress, interdependence and perceived emotional support.
<p>Correlations between diabetes-related distress, interdependence and perceived emotional support.</p
Distribution plots and Pearson's correlation coefficients to show the association between PAID and interdependence after adjusting for PES, self-esteem, sex, age and education level in Japanese (A) and Americans (B), between PAID and PES after adjusting for interdependence, self-esteem, sex, age and education level in Japanese (C) and Americans (D). PAID, the Problem Areas in Diabetes; PES, perceived emotional support.
<p>Distribution plots and Pearson's correlation coefficients to show the association between PAID and interdependence after adjusting for PES, self-esteem, sex, age and education level in Japanese (A) and Americans (B), between PAID and PES after adjusting for interdependence, self-esteem, sex, age and education level in Japanese (C) and Americans (D). PAID, the Problem Areas in Diabetes; PES, perceived emotional support.</p
The Effect of Novel Glucose Monitoring System (Flash Glucose Monitoring) on Mental Well-being and Treatment Satisfaction in Japanese People with Diabetes
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Prognostic factors and outcomes in Japanese lung transplant candidates with interstitial lung disease
<div><p>Objective</p><p>Young patients with advanced interstitial lung disease (ILD) are potential candidates for cadaveric lung transplantation. This study aimed to examine clinical features, outcomes, and prognostic factors in Japanese ILD patients awaiting lung transplantation.</p><p>Methods</p><p>We investigated the clinical features and outcomes of 77 consecutive candidates with ILD who were referred to Kyoto University Hospital and subsequently actively listed for lung transplant in the Japan Organ Transplant Network between 2010 and 2014.</p><p>Results</p><p>Of the 77 candidates, 33 had idiopathic pulmonary fibrosis (IPF) and 15 had unclassifiable ILD. During the observational period, 23 patients (30%) received lung transplantations and 49 patients (64%) died before transplantation. Of the 33 patients with IPF, 13 (39%) had a family history of ILD and 13 (39%) had an āinconsistent with usual interstitial pneumonia patternā on high-resolution computed tomography (HRCT). The median survival time from registration was 16.7 months, and mortality was similar among patients with IPF, unclassifiable ILD, and other ILDs. Using a multivariate stepwise Cox proportional hazards model, 6-min walking distance was shown to be an independent prognostic factor in candidates with ILD (per 10 m, hazard ratio (HR): 0.97; 95% confidence interval (CI): 0.95ā0.99, p<0.01), while lower body mass index (HR: 0.83; 95% CI: 0.72ā0.95, p < 0.01) independently contributed to mortality in patients with IPF.</p><p>Conclusions</p><p>Japanese patients with ILD awaiting transplantation had very poor outcomes regardless of their specific diagnosis. A substantial percentage of IPF patients had an atypical HRCT pattern. 6-min walking distance in ILD patients and body mass index in IPF patients were independent predictors of mortality.</p></div