388 research outputs found

    Temporal Variability of Ion Acceleration and Abundances in Solar Flares

    Get PDF
    solar flares accelerate both ions and electrons to high energies, and their x-ray and gamma-ray signatures not only probe the relationship between their respective acceleration, but also allow for the measurement of accelerated and ambient abundances. RHESSI observations have shown a striking close linear correlation of gamma-ray line fluence from accelerated ions > approx 20 MeV and bremsstrahlung emission from relativistic accelerated electrons >300 kev, when integrated over complete flares, suggesting a common acceleration mechanism. SMM/GRS observations, however, show a weaker correlation, and this discrepancy might be associated with previously observed electron-rich episodes within flares and/or temporal variability of gamma-ray line fluxes over the course of flares. We use the latest RHESSI gamma-ray analysis techniques to study the temporal behavior of the RHESSI flares, and determine what changes can be attributed to an evolving acceleration mechanism or to evolving abundances. We also discuss possible explanations for changing abundances

    Sustaining high-solar-activity research

    Full text link
    Research efforts that require observations of high solar activity, such as multiwavelength studies of large solar flares and CMEs, must contend with the 11-year solar cycle to a degree unparalleled by other segments of heliophysics. While the "fallow" years around each solar minimum can be a great time frame to build the next major solar observatory, the corresponding funding opportunity and any preceding technology developments would need to be strategically timed. Even then, it can be challenging for scientists on soft money to continue ongoing research efforts instead of switching to other, more consistent topics. The maximum of solar cycle 25 is particularly concerning due to the lack of a US-led major mission targeting high solar activity, which could result in significant attrition of expertise in the field. We recommend the development of a strategic program of missions and analysis that ensures optimal science return for each solar maximum while sustaining the research community between maxima.Comment: White paper submitted to the Decadal Survey for Solar and Space Physics (Heliophysics) 2024-2033; 4 pages, 1 figur

    Characterizing and correcting electron and hole trapping in germanium cross-strip detectors

    Full text link
    We present measurements of electron and hole trapping in three COSI germanium cross-strip detectors. By characterizing the relative charge collection efficiency (CCE) as a function of interaction depth, we show that intrinsic trapping of both electrons and holes have significant effects on the spectroscopic performance of the detectors. We find that both the electron and hole trapping vary from detector to detector, demonstrating the need for empirical trapping measurements and corrections. Using our measurements of charge trapping, we develop a continuous depth-dependent second-order energy correction procedure. We show that applying this empirical trapping correction produces significant improvements to spectral resolution and to the accuracy of the energy reconstruction.Comment: 17 pages, 3 figures, 1 table, in press in NIM

    A Deep Learning Approach for Predicting Antidepressant Response in Major Depression Using Clinical and Genetic Biomarkers

    Get PDF
    In the wake of recent advances in scientific research, personalized medicine using deep learning techniques represents a new paradigm. In this work, our goal was to establish deep learning models which distinguish responders from non-responders, and also to predict possible antidepressant treatment outcomes in major depressive disorder (MDD). To uncover relationships between the responsiveness of antidepressant treatment and biomarkers, we developed a deep learning prediction approach resulting from the analysis of genetic and clinical factors such as single nucleotide polymorphisms (SNPs), age, sex, baseline Hamilton Rating Scale for Depression score, depressive episodes, marital status, and suicide attempt status of MDD patients. The cohort consisted of 455 patients who were treated with selective serotonin reuptake inhibitors (treatment-response rate = 61.0%; remission rate = 33.0%). By using the SNP dataset that was original to a genome-wide association study, we selected 10 SNPs (including ABCA13 rs4917029, BNIP3 rs9419139, CACNA1E rs704329, EXOC4 rs6978272, GRIN2B rs7954376, LHFPL3 rs4352778, NELL1 rs2139423, NUAK1 rs2956406, PREX1 rs4810894, and SLIT3 rs139863958) which were associated with antidepressant treatment response. Furthermore, we pinpointed 10 SNPs (including ARNTL rs11022778, CAMK1D rs2724812, GABRB3 rs12904459, GRM8 rs35864549, NAALADL2 rs9878985, NCALD rs483986, PLA2G4A rs12046378, PROK2 rs73103153, RBFOX1 rs17134927, and ZNF536 rs77554113) in relation to remission. Then, we employed multilayer feedforward neural networks (MFNNs) containing 1–3 hidden layers and compared MFNN models with logistic regression models. Our analysis results revealed that the MFNN model with 2 hidden layers (area under the receiver operating characteristic curve (AUC) = 0.8228 ± 0.0571; sensitivity = 0.7546 ± 0.0619; specificity = 0.6922 ± 0.0765) performed maximally among predictive models to infer the complex relationship between antidepressant treatment response and biomarkers. In addition, the MFNN model with 3 hidden layers (AUC = 0.8060 ± 0.0722; sensitivity = 0.7732 ± 0.0583; specificity = 0.6623 ± 0.0853) achieved best among predictive models to predict remission. Our study indicates that the deep MFNN framework may provide a suitable method to establish a tool for distinguishing treatment responders from non-responders prior to antidepressant therapy

    Modelling Solar Energetic Neutral Atoms from Solar Flares and CME-driven Shocks

    Full text link
    We examine the production of energetic neutral atoms (ENAs) in solar flares and CME-driven shocks and their subsequent propagation to 1 au. Time profiles and fluence spectra of solar ENAs at 1 au are computed for two scenarios: 1) ENAs are produced downstream at CME-driven shocks, and 2) ENAs are produced at large-scale post-flare loops in solar flares. Both the time profiles and fluence spectra for these two scenarios are vastly different. Our calculations indicate that we can use solar ENAs as a new probe to examine the underlying acceleration process of solar energetic particles (SEPs) and to differentiate the two accelertion sites: large loops in solar flares and downstream of CME-driven shocks, in large SEP events.Comment: 11 pages, updated figures and paper is accepted by Ap

    The network structure of visited locations according to geotagged social media photos

    Full text link
    Businesses, tourism attractions, public transportation hubs and other points of interest are not isolated but part of a collaborative system. Making such collaborative network surface is not always an easy task. The existence of data-rich environments can assist in the reconstruction of collaborative networks. They shed light into how their members operate and reveal a potential for value creation via collaborative approaches. Social media data are an example of a means to accomplish this task. In this paper, we reconstruct a network of tourist locations using fine-grained data from Flickr, an online community for photo sharing. We have used a publicly available set of Flickr data provided by Yahoo! Labs. To analyse the complex structure of tourism systems, we have reconstructed a network of visited locations in Europe, resulting in around 180,000 vertices and over 32 million edges. An analysis of the resulting network properties reveals its complex structure.Comment: 8 pages, 3 figure

    SuperHERO: The Next Generation Hard X-ray HEROES Telescope

    Get PDF
    SuperHERO is a new high-sensitivity Long Duration Balloon (LDB)-capable, hard-x-ray (20-75 keV) telescope for making novel astrophysics and heliophysics observations. The proposed SuperHERO payload will be developed jointly by the Astrophysics Office at NASA Marshall Space Flight Center, the Solar Physics Laboratory and Wallops Flight Facility at NASA Goddard Space Flight Center. SuperHERO is a follow-on payload to the High Energy Replicated Optics to Explore the Sun (HEROES) balloon-borne telescope that recently launched from Fort Sumner, NM in September of 2013. The HEROES core instrument is a hard x-ray telescope consisting of x-ray 109 optics configured into 8 modules. Each module is aligned to a matching gas-filled detector at a focal length of 6 m. SuperHERO will make significant improvements to the HEROES payload, including: new solid-state multi-pixel CdTe detectors, additional optics, the Wallops Arc-Second Pointer, alignment monitoring systems and lighter gondola

    CdTe Focal Plane Detector for Hard X-Ray Focusing Optics

    Get PDF
    The demand for higher resolution x-ray optics (a few arcseconds or better) in the areas of astrophysics and solar science has, in turn, driven the development of complementary detectors. These detectors should have fine pixels, necessary to appropriately oversample the optics at a given focal length, and an energy response also matched to that of the optics. Rutherford Appleton Laboratory have developed a 3-side buttable, 20 millimeter x 20 millimeter CdTe-based detector with 250 micrometer square pixels (80 x 80 pixels) which achieves 1 kiloelectronvolt FWHM (Full-Width Half-Maximum) @ 60 kiloelectronvolts and gives full spectroscopy between 5 kiloelectronvolts and 200 kiloelectronvolts. An added advantage of these detectors is that they have a full-frame readout rate of 10 kilohertz. Working with NASA Goddard Space Flight Center and Marshall Space Flight Center, 4 of these 1 millimeter-thick CdTe detectors are tiled into a 2 x 2 array for use at the focal plane of a balloon-borne hard-x-ray telescope, and a similar configuration could be suitable for astrophysics and solar space-based missions. This effort encompasses the fabrication and testing of flight-suitable front-end electronics and calibration of the assembled detector arrays. We explain the operation of the pixelated ASIC readout and measurements, front-end electronics development, preliminary X-ray imaging and spectral performance, and plans for full calibration of the detector assemblies. Work done in conjunction with the NASA Centers is funded through the NASA Science Mission Directorate Astrophysics Research and Analysis Program
    corecore