33 research outputs found
On the smoothness of Orlicz sequence spaces equipped with Orlicz norm
We give a criterion of smoothness of Orlicz sequence spaces with Orlicz norm
Case report: BCR-ABL-positive acute lymphoblastic leukemia with bone destruction: a treatment dilemma
Although bone destruction and hypercalcemia without acute peripheral blast BCR-ABL-positive acute lymphoblastic leukemia (ALL) have been reported in children, they are rare in adults. Herein, we describe a case of BCR-ABL positive ALL with a triploid karyotype, WT1, and CDKN2A mutations with hypercalcemia and bone destruction as the first manifestations. Complete remission (CR) was achieved by induction chemotherapy. BCR-ABL turned negative after treatment with dasatinib. However, computed tomography and whole-body bone scan showed extensive bone destruction. Additionally, bone biopsy showed leukemic infiltration. After treatment with dasatinib and VMCP, leukemia recurred with positive BCR-ABL. The T315I mutation occurred. The patient was surgically diagnosed with calculous cholecystitis and achieved CR2 by postoperative orebatinib and VP regimens. Later, the patient died due to a severe pulmonary infection. BCR-ABL-positive ALL with bone destruction is rare and difficult to control using tyrosine kinase inhibitor chemotherapy alone. Therefore, further exploration of more effective treatments is needed
The Nearest Neutron Star Candidate in a Binary Revealed by Optical Time-domain Surveys
Recent studies have revealed the global deposition on Earth of radioactive
elements (e.g., Fe) resulting from the metal-enriched ejecta of nearby
(within pc) supernova explosions. The majority of neutron stars in
our Solar neighborhood remain to be discovered. Here we report the discovery of
the nearest ( pc) neutron star candidate in the single-lined
spectroscopic binary LAMOST J235456.76+335625.7 (hereafter J2354). Utilizing
the multi-epoch spectra and high-cadence periodic light curves, we measure the
mass of the visible star () and determine
the mass function of the invisible object ,
i.e., the mass of the unseen compact object is $M_{\rm inv} \geq 1.26 \pm 0.03\
M_{\odot}0.12.4<10^{30}\ {\rm erg\ s^{-1}}1.4<6.8\times 10^{23}\ {\rm erg\ s^{-1}}$). Hence, the
neutron star candidate in J2354 can only be discovered via our time-resolved
observations. The alternative scenario involving a nearby supramassive cold
white dwarf cannot be fully excluded. Our discovery demonstrates a promising
way to unveil the missing population of backyard inactive neutron stars or
supramassive cold white dwarfs in binaries by exploring the optical time
domain, thereby facilitating understanding of the supernovae explosion and
metal-enrichment history in our Solar neighborhood.Comment: 35 pages, 8 figures, to be submitte
K-extreme point of generalized orlicz sequence spaces with Luxemburg norm
In this paper,we give necessary and sufficient conditions in order that a
point is a k-extreme point in generalized
Orlicz sequence spaces equipped with the Luxemburg norm, combing the methods used
in classical Orlicz spaces and new methods introduced especially for
generalized ones. The results indicate the difference between the
classical Orlicz spaces and generalized Orlicz spaces
On the uniformly normal structure of Orlicz spaces with Orlicz norm
summary:We prove that in Orlicz spaces endowed with Orlicz norm the uniformly normal structure is equivalent to the reflexivity
Weakly compact sets in Orlicz sequence spaces
summary:We combine the techniques of sequence spaces and general Orlicz functions that are broader than the classical cases of -functions. We give three criteria for the weakly compact sets in general Orlicz sequence spaces. One criterion is related to elements of dual spaces. Under the restriction of , we propose two other modular types that are convenient to use because they get rid of elements of dual spaces. Subsequently, by one of these two modular criteria, we see that a set in Riesz spaces is relatively sequential weakly compact if and only if it is normed bounded, that says . The result again confirms the conclusion of the Banach-Alaoglu \hbox {theorem}