Baseline characteristics of 54 schoolchildren followed from April to November 2008, in an endemic area for malaria (municipality of Careiro, Amazonas, Brazil), according to the helminth detected at stool examination during <i>P. vivax</i>.

<p>Baseline characteristics of 54 schoolchildren followed from April to November 2008, in an endemic area for malaria (municipality of Careiro, Amazonas, Brazil), according to the helminth detected at stool examination during <i>P. vivax</i>.</p

Correlation between parasitemia and hemoglobin.

<p>Correlation between parasitemia and hemoglobin during the first malarial attack in children without helminthes (A) and with helminthes (B).</p

Algorithm of the study, describing the details of eligible, enrolled and analyzed children.

<p>Algorithm of the study, describing the details of eligible, enrolled and analyzed children.</p

Survival analysis of the time for the first malarial episode.

<p>Kaplan-Meier survival analysis showing the time elapsed from the baseline cross-sectional to the first malarial infection (in days) in 54 schoolchildren followed from April to November 2008, with and without <i>Ascaris lumbricoides</i> (A), hookworm (B) and <i>Trichuris trichiura</i> (C).</p

MOESM2 of Declining malaria transmission in rural Amazon: changing epidemiology and challenges to achieve elimination

Additional file 2: Figure S2. Survival analysis showing the risk of Plasmodium vivax recurrence according to bed net use

Mean (± standard error of the mean) hemoglobin concentration before (baseline Hb) and during (malarial Hb) the first <i>P. vivax</i> acute attack in 54 schoolchildren followed from April to November 2008, in an endemic area for malaria (Municipality of Careiro, Amazonas, Brazil), according to the helminth detected at stool examination.

<p>Mean (± standard error of the mean) hemoglobin concentration before (baseline Hb) and during (malarial Hb) the first <i>P. vivax</i> acute attack in 54 schoolchildren followed from April to November 2008, in an endemic area for malaria (Municipality of Careiro, Amazonas, Brazil), according to the helminth detected at stool examination.</p

Detailed clinical information from 24 children 0–14 years old, admitted to any of the pediatric or neonatal ICUs in Manaus, from 2004 to 2009, with parasitological diagnosis of <i>P. vivax</i>.

<p>y years; mo: months; d: days; NA: Non-available; ARDS: Acute Respiratory Distress Syndrome; ARF: Acute Renal Failure; PIM: Pediatric Index of Mortality; ITP: Immune Trombocytopenic Purpura.</p>*<p><b>Viral encephalitis</b> confirmed by autopsy; diagnosis of <b>malnutrition</b> confirmed by body mass index (BMI) Z-score <−2; <b>rotavirus gastroenteritis</b> confirmed by immunochromatographic rapid test in the stool; <b>cystic fibrosis</b> suggested by lung biopsy; <b>sepsis</b> confirmed by two positive blood cultures; <b>G6PD deficiency</b> confirmed by qualitative Brewer's test; <b>lung empyema</b> confirmed by computed tomography; <b>urosepsis</b> confirmed by both positive urine and blood culture; <b>ITP</b> confirmed by ASH criteria; ARDS defined as acute bilateral lung infiltrates and a PaO₂∶FiO₂<200 mmHg.</p

Detailed laboratorial information from 24 children 0–14 years old, at the moment of admission to any of the pediatric or neonatal ICUs in Manaus, from 2004 to 2009, with parasitological diagnosis of <i>P. vivax</i>.

<p>Hb: hemoglobin; ALT: alanine aminotransferase; AST: aspartate aminotrasferase.</p

Flow diagram of patients admitted to ICUs enrolled in the analysis.

<p>Flow diagram of patients admitted to ICUs enrolled in the analysis.</p

Univariate and multivariate (logistic regression) analysis of factors associated to the admission in the ICUs of children 0–14 years old with <i>P. vivax</i> infection, in Manaus, from 2004 to 2009.

<p>Univariate and multivariate (logistic regression) analysis of factors associated to the admission in the ICUs of children 0–14 years old with <i>P. vivax</i> infection, in Manaus, from 2004 to 2009.</p