Chronic non puerperal uterine inversion secondary to uterine leiomyoma misdiagnosed as advanced cervical cancer: a rare case report

Uterine inversion is an uncommon complication of parturition which often occurs in the immediate postpartum period. The chronic non puerperal uterine inversion is a rare gynaecological clinical condition which usually results from tumour arising from the fundus of the uterus. Here we are present a case of 45 year old lady with non-puerperal chronic uterine inversion secondary to fundal sub mucous fibroid polyp which was initially misdiagnosed as carcinoma cervix. An attempt at vaginal restoration and removal was difficult. Hysterectomy was done by vaginal approach. Pre and Postoperative course in the hospital was uneventful. Early diagnosis and appropriate surgical treatment of the inverted uterus are important to prevent further complications

The colors of life: An interdisciplinary artist-in-residence project to research fungal pigments as a gateway to empathy and understanding of microbial life

Background: Biological pigmentation is one of the most intriguing traits of many fungi. It holds significance to scientists, as a sign of biochemical metabolism and organism-environment interaction, and to artists, as the source of natural colors that capture the beauty of the microbial world. Furthermore, the functional roles and aesthetic appeal of biological pigmentation may be a path to inspiring human empathy for microorganisms, which is key to understanding and preserving microbial biodiversity. A project focused on cross-species empathy was initiated and conducted as part of an artist-in-residence program in 2021. The aim of this residency is to bridge the current divide between science and art through interdisciplinary practice focused on fungi. Results: The residency resulted in multiple products that are designed for artistic and scientific audiences with the central theme of biological pigmentation in fungi and other microorganisms. The first product is a video artwork that focuses on Aspergillus niger as a model organism that produces melanin pigment in a biosynthetic process similar to that of humans. The growth and morphology of this commonplace organism are displayed through video, photo, animation, and time-lapse footage, inviting the viewer to examine the likenesses and overlaps between humans and fungi. The second product is The Living Color Database, an online compendium of biological colors for scientists, artists, and designers. It links organisms across the tree of life, focusing on fungi, bacteria, and archaea, and the colors they express through biological pigmentation. Each pigment is represented in terms of its chemistry, its related biosynthesis, and its color expressions according to different indices: HEX, RGB, and Pantone. It is available at color.bio. Conclusions: As fungal biotechnology continues to mature into new application areas, it is as important as ever that there is human empathy for these organisms to promote the preservation and appreciation of fungal biodiversity. The products presented here provide paths for artists, scientists, and designers to understand microorganisms through the lens of color, promoting interspecies empathy through research, teaching, and practice.TU Berlin, Open-Access-Mittel - 202

Gate-to-grave assessment of plastic from recycling to manufacturing of TENG: a comparison between India and Singapore

This study assesses the viability of recycled plastic-based triboelectric nanogenerators (TENGs) for sustainable energy harvesting in India and Singapore, concurrently examining plastic waste management. Using material flow analysis and life cycle assessment, the findings revealed that in Singapore, waste-to-energy incineration has a lower environmental impact than landfilling and mechanical recycling, attributed to natural gas usage. In India, recycling offsets impacts from incineration and landfilling, contributing to a lower net environmental impact. Economic performance of a TENG module from PET recyclates showed a 20% carbon footprint reduction when scaling up from lab to industrial “freeze-drying” processes. Key challenges in TENG manufacturing processes are also assessed for future development. This research highlights the potential of recycled plastic-based TENGs in sustainable energy and waste management

To compare the detection of <i>S. aureus</i> carriage in Healthcare Workers of Pediatric Intensive Care Units using Robertson’s Cooked Meat medium with and without 10% NaCl

Background: about 20% of the world’s population has been colonized by Staphilococcus aureus in the long term. Nasal carriage of S. aureus is an important risk factor for sepsis. In most cases, asymptomatic colonized Healthcare Workers (HCWs) can serve as reservoirs of infection for spreading S. aureus strains to susceptible patients. Aims: detecting S. aureus carriage in hospital staff working in Neonatal (NICU) and Pediatric Intensive Care Unit (PICU) in a tertiary care hospital. Materials and Methods: swabs from the anterior nares and web spaces of both hands of HCWs were processed. Swabs were cultured on Mannitol Salt Agar (MSA) with & without enrichment by RCM with 10% NaCl. After incubating for 48 hours, subculture from RCM was done on MSA. S. aureus was identified using standard microbiological techniques. The antimicrobial susceptibility testing was carried out as per Clinical and Laboratory Standards Institute (CLSI) 2024 guidelines. Results: S. aureus carriage rate was 18.8%. The carriage was higher in males than in females. It was higher in residents (38.1%) than in nursing staff (5.6%). Higher isolation of S. aureus was observed after enrichment with 10% NaCl. Methicillin resistance was as high as 77.8% in S. aureus isolates from HCW carriers. All isolates were found sensitive to mupirocin. Conclusions: to monitor the carriage of S. aureus in HCWs, RCM with 10% NaCl should always be used along with MSA. Eighteen point eight percent of HCWs in this study were found to be carriers of S. aureus. The study emphasizes the need for regular surveillance of HCWs. Methicillin resistance was very high (77.8%). Healthcare centers are supposed to monitor patients continuously and provide proper treatment

Grown, Printed, and Biologically Augmented: An Additively Manufactured Microfluidic Wearable, Functionally Templated for Synthetic Microbes

Despite significant advances in synthetic biology at industrial scales, digital fabrication challenges have, to date, precluded its implementation at the product scale. We present, Mushtari, a multimaterial 3D printed fluidic wearable designed to culture microbial communities. Thereby we introduce a computational design environment for additive manufacturing of geometrically complex and materially heterogeneous fluidic channels. We demonstrate how controlled variation of geometrical and optical properties at high spatial resolution can be achieved through a combination of computational growth modeling and multimaterial bitmap printing. Furthermore, we present the implementation, characterization, and evaluation of support methods for creating product-scale fluidics. Finally, we explore the cytotoxicity of 3D printed materials in culture studies with the model microorganisms, Escherichia coli and Bacillus subtilis. The results point toward design possibilities that lie at the intersection of computational design, additive manufacturing, and synthetic biology, with the ultimate goal of imparting biological functionality to 3D printed products.National Science Foundation (U.S.) (DGE1144152)United States. Department of Energy (DE-SC0012658

Making data matter: Voxel printing for the digital fabrication of data across scales and domains

We present a multimaterial voxel-printing method that enables the physical visualization of data sets commonly associated with scientific imaging. Leveraging voxel-based control of multimaterial three-dimensional (3D) printing, our method enables additive manufacturing of discontinuous data types such as point cloud data, curve and graph data, image-based data, and volumetric data. By converting data sets into dithered material deposition descriptions, through modifications to rasterization processes, we demonstrate that data sets frequently visualized on screen can be converted into physical, materially heterogeneous objects. Our approach alleviates the need to postprocess data sets to boundary representations, preventing alteration of data and loss of information in the produced physicalizations. Therefore, it bridges the gap between digital information representation and physical material composition. We evaluate the visual characteristics and features of our method, assess its relevance and applicability in the production of physical visualizations, and detail the conversion of data sets for multimaterial 3D printing. We conclude with exemplary 3D-printed data sets produced by our method pointing toward potential applications across scales, disciplines, and problem domains

Calorimetry Task Force Report

In this note we summarize the studies and recommendations of the calorimeter simulation task force (CaloTF). The CaloTF was established in February 2008 in order to understand and reconcile the discrepancies observed between the CMS calorimetry simulation and the test beam data recorded during 2004 and 2006. As the result of studies by the CaloTF a new version of Geant4 was developed and introduced in the CMS detector simulation leading to significanly better agreement with test beam data. Fast and flexible parameterizations describing showering in the calorimeter are introduced both in the Full Simulation (with a Gflash-like approach) and in the Fast Simulation. The CaloTF has developed a strategy to rapidly tune the CMS calorimeter simulation using the first LHC collision data when it becomes available. The improvements delivered by the CaloTF have been implemented in the software release CMSSW 2.1.0

Weed dynamics, wheat (Triticum aestivum) yield and irrigation water-use efficiency under conservation agriculture

A field experiment was conducted to evaluate the impacts of a 12-year old conservation agriculture (CA)- based pigeon pea-wheat system on weeds, wheat crop, and resource use during winter (rabi) 2021–22. Results indicated that surface retention of residue irrespective of ZT permanent bed and N dose led to significant reduction in weed interference at 60 DAS. CA-based systems reduced weed density and dry weight considerably than CT. CA- based systems led to significantly higher wheat grain yield (by 11.6–14.9%) and net B:C (by 24.0 –28.0%) than CT, and PFBR100N and PBBR100N were slightly superior to others. PBBR100N and PBBR75N had lower irrigation water use and significantly higher irrigation water productivity than CT. Contrast analysis showed that wheat yield and water productivity were comparable between 75% N and 100% N in CA, indicating a saving of 25% N under CA

The CMS Outer Hadron Calorimeter

The CMS hadron calorimeter is a sampling calorimeter with brass absorber and plastic scintillator tiles with wavelength shifting fibres for carrying the light to the readout device. The barrel hadron calorimeter is complemented with a outer calorimeter to ensure high energy shower containment in CMS and thus working as a tail catcher. Fabrication, testing and calibrations of the outer hadron calorimeter are carried out keeping in mind its importance in the energy measurement of jets in view of linearity and resolution. It will provide a net improvement in missing \et measurements at LHC energies. The outer hadron calorimeter has a very good signal to background ratio even for a minimum ionising particle and can hence be used in coincidence with the Resistive Plate Chambers of the CMS detector for the muon trigger