Kasabach-Merritt syndrome arising from an Enteroatmospheric Fistula

Kasabach-Merritt syndrome (KMS) is a rare, life-threatening condition that is characterized by profound thrombocytopenia, hypofibrinogenemia, elevated partial thromboplastin time, and may also be associated with microangiopathic hemolytic anemia. It is well established that this phenomenon is notably associated with the vascular tumors kaposiform hemangioendothelioma and tufted angioma; however, recent literature has suggested its presence in the settings of various vascular malformations (i.e. without neoplastic proliferation of endothelial cells). This report focuses on a patient in the first year of life, who experienced a chronic, consumptive coagulopathy in the setting of a highly vascular enteroatmospheric fistula. Sharing many features with the aforementioned syndrome, this anomaly suggests a novel association of the Kasabach-Merritt phenomenon with a unique vascular malformation. Although potentially lethal, Kasabach-Merritt syndrome can resolve with appropriate diagnosis and management; uncovering new associations can help to improve recognition and treatment in future cases

Digital Speech Interpolation Advantage of Statistical Time Division Multiplexer

This paper discusses Digital Speech Interpolation (DSI) advantage of Statistical Time Division Multiplexer (STDM) for Random Packet Loss scenarios. In order to harness this advantage each source speech is compressed at 6.4 kbps, Voice Activity Detector (VAD) is used for each source, and packet loss mechanism is introduced to achieve maximum DSI advantage. It is observed that for maximum of 9 users channel capacity, extra 3 users, i.e. total 12 users can be accommodated with 3% speech frame losses, which results in an advantage of 12/9 = 1.33

Britain can promote private investment and economic growth. Here’s how

The UK investment ecosystem needs rewiring across the board to increase firms’ desire to invest in productive and sustainable assets, and to enhance their ability to do so. Paul Brandily, Mimosa Distefano, Krishan Shah, Gregory Thwaites and Anna Valero set out why this matters and what to do about it

Enduring strengths: Analysing the UKs current and potential economic strengths, and what they mean for its economic strategy, at the start of the decisive decade

Key to building a new economic strategy which can revitalise the UK economy after a decade of stagnation is understanding our current strengths, how these strengths evolve, and the trade-offs they present.The report uses global data on trade in goods and services and patenting to uncover where the UK's relative strengths lie; we study the extent to which these strengths have changed over time and compare with international peers; and undertake several deep dives into the areas in which the UK has developed a specialism. Finally we consider what the UK's mix of specialisms means for a wider economic strategy

Enduring strengths: analysing the UK’s current and potential economic strengths, and what they mean for its economic strategy, at the start of the decisive decade

Key to building a new economic strategy which can revitalise the UK economy after a decade of stagnation is understanding our current strengths, how these strengths evolve, and the trade-offs they present. The report uses global data on trade in goods and services and patenting to uncover where the UK’s relative strengths lie; we study the extent to which these strengths have changed over time and compare with international peers; and undertake several deep dives into the areas in which the UK has developed a specialism. Finally we consider what the UK’s mix of specialisms means for a wider economic strategy

The UK must recognise its enduring economic strengths

A decade of stagnant living standards, weak productivity and low investment combined with a coming decade of major change – driven by Covid-19, Brexit and the need for accelerated action on Net Zero – mean that it is crucial for the UK to renew its economic strategy. Josh De Lyon, Ralf Martin, Juliana Oliveira-Cunha, Arjun Shah, Krishan Shah, Gregory Thwaites, and Anna Valero argue that the UK is a services-exporting superpower, but it is not narrowly focused on finance and has strengths outside the service sector, for example in clean technologies and pharmaceuticals. A renewed economic strategy cannot ignore the UK’s history and current endowments: it needs to build on these areas of strength and protect them from new risks

Bridging the productivity gap between different areas in the UK

An economic strategy that helps the UK respond to change and tackle stagnant living standards and weak productivity will need to address stubborn spatial disparities in economic performance across the UK. Addressing these disparities requires a good understanding of their extent, causes and consequences. Paul Brandily, Mimosa Distefano, Hélène Donnat, Immanuel Feld, Henry G. Overman, and Krishan Shah outline what is known about disparities in productivity across the country, the factors that determine them, and the changes that would be needed to reduce them

Time for a strategy to boost productivity in Manchester and beyond

The UK has a significant productivity problem and the poor performance of the nation’s largest cities outside the capital contribute to this problem. Paul Brandily, Mike Brewer, Nye Cominetti, Matt Coombes, Adam Corlett, Lindsay Judge, Felicia Odamtten, Henry Overman, Cara Pacitti, Gui Rodrigues, Krishan Shah, Paul Swinney and Lalitha Try set out what change would be needed to set Greater Manchester on a plausible path for growth

A conceptual framework for determinants of customer satisfaction of fixed-line telecom services in Pakistan

With the progression of communication technologies, there has been a decline in people's utilization of fixed-line telephones. It is essential to ascertain the fundamental causes underlying this phenomenon. There are numerous assumptions that service providers tend to favor their interests. Gaining an understanding of the factors that contribute to client satisfaction may require a significant investment of effort. Consequently, this study aims to ascertain the determinants that impact consumers' happiness with their fixed-line telecommunications service. In order to achieve the objectives of the research, a theoretical framework is presented whereby consumer satisfaction is considered the dependent variable. At the same time, responsiveness, perceived value, perceived service quality, and staff attitude are regarded as independent variables. The primary objective of this study is to ascertain the key factors that significantly influence Customer Satisfaction with Fixed-Line Telecom Services in Pakistan