4 research outputs found

    Additional file 5: Figure S2. of miR-539 inhibits prostate cancer progression by directly targeting SPAG5

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    miR-539 is downexpressed in primary PCa and metastatic PCa. miR-539 level was gradually decreased in normal prostate, primary PCa, and metastatic PCa samples. (JPG 173 kb

    Additional file 3: Table S3. of miR-539 inhibits prostate cancer progression by directly targeting SPAG5

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    Prognostic value of SPAG5 protein expression for the overall survival in univariate and multivariate analyses by Cox regression. (DOC 34 kb

    Additional file 2: Table S2. of miR-539 inhibits prostate cancer progression by directly targeting SPAG5

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    Prognostic value of SPAG5 protein expression for the biochemical recurrence free survival in univariate and multivariate analyses by Cox regression. (DOC 34 kb

    Additional file 4: Figure S1. of miR-539 inhibits prostate cancer progression by directly targeting SPAG5

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    miR-539 inhibits PCa cell proliferation, migration and invasion by targeting SPAG5 in vitro. A, Ectopic expression of miR-539 can mimic the suppression of colony formation induced by SPAG5 knockdown in PC-3 and LNCaP cells; B, Ectopic expression of miR-539 can mimic the suppression of migration activity induced by SPAG5 knockdown in PC-3 and LNCaP cells; C, Ectopic expression of miR-539 can mimic the suppression of invasion activity induced by SPAG5 knockdown in PC-3 and LNCaP cells; D, The efficiency of SPAG5 knockdown and ectopic expression of miR-539 was confirmed at protein level by western blot. (JPG 145 kb
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