Serum anti-mullerian hormone levels in the main phenotypes of polycystic ovary syndrome

Objective: To characterize the difference in circulating anti-Mallerian hormone (AMH) levels between the main polycystic ovary syndrome (PCOS) phenotypic groups and evaluate the role of AMH in predicting the severity of PCOS

Serum anti-mullerian hormone levels in the main phenotypes of polycystic ovary syndrome

Objective: To characterize the difference in circulating anti-Mallerian hormone (AMH) levels between the main polycystic ovary syndrome (PCOS) phenotypic groups and evaluate the role of AMH in predicting the severity of PCOS

Elevated serum levels of anti-Mullerian hormone can be introduced as a new diagnostic marker for polycystic ovary syndrome

ObjectiveTo determine the possible role of anti-Mullerian hormone (AMH) in the diagnosis of polycystic ovary syndrome (PCOS) with a larger population of women and to evaluate its role as a new diagnostic marker

Effect of different hormonal therapies on thyroid function in surgical menopause - Short-term results

To determine the effects of different hormone replacement therapy (HRT) regimens on thyroid function in surgical menopause. STUDY DESIGN: In a randomized, controlled study, 59 euthyroid women with surgical menopause were randomized to an estrogenonly (n=20), tibolone (n=20) or calcium-only (n = 19) group. On the 5th postoperative day and 4th and 12th weeks, serum E-2, TSH, free T3 and free T4 levels were determined. RESULTS: Although the initial and week 4 serum E-2, TSH, free T3 and free T4 levels were comparable, the week 12 serum E-2 and TSH levels were different between the subjects on estrogen therapy and those receiving tibolone or calcium only (p = 0.008 and 0.000, respectively). Serum E-2 levels were higher and TSH levels lower in subjects receiving estrogen. Moreover, serum TSH levels correlated negatively with serum E-2 levels in the 12th week of estrogen use (r = -0.354, p = 0.006). TSH increased in the tibolone group as compared to the estrogen group but was still lower than in the calcium-only group; however, the differences were not statistically significant. CONCLUSION: Irrespective of different regimens, HRT does not have an important short-term effect on thyroid function in women with surgical menopause

Is there any correlation between amh and obesity in premenopausal women?

To evaluate the correlation between the levels of anti-mullerian hormone and body mass index between obese and non-obese premenopausal women

Mammographic changes in women on hormonal replacement therapy

Objectives: In the present retrospective study, we aimed to determine the frequency and the types of mammographic changes of breast parenchyma in women receiving hormone replacement therapy (HRT). We also investigated whether there was an association between mammographic changes and some clinical and hormonal characteristics of the women on HRT. Methods: One-hundred and eight women were included into the study. Of the 108 women, 19 were climacteric, four premature menopause, 50 spontaneous menopause and 35 surgical menopause. Prior to the start of HRT, an initial mammography was performed and it was repeated at 6- to 18-month intervals according to the women's status. Estrogen alone was started for 35 surgical menopause women and a combination of estrogen plus progesterone for the remaining 73 women. Results: Group I consisted of 96 women with no parenchymal changes or a decrease in parenchymal density on mammography, whereas group II consisted of 12 women with an increase in parenchymal density (11%) during the mean period of 24 months. Endogenous E2 levels were significantly higher in group II than in group I (52.4 +/- 42.3 pg/ml vs. 32.3 +/- 29.3 pg/ml, P < 0.05). Climacterium or types of menopause did not affect the mammographical density changes. Neither the type nor the duration of HRT had an effect on mammographic density increase. Conclusions: We concluded that the endogenous E2 level might be an important role in screening the women mammographically. Long-term follow-up studies were concluded to be needed in order to evaluate the effects of HRT on mammographic changes