35 research outputs found
Business Librarians and New Academic Program Review
The article aims to examine the role business librarians play in the new academic program proposal process on university and college campuses. Results of a nationwide online survey showed that current practices in this critical area varied. While over 60% of the respondents thought that librarians should play a part in the proposal process, over 65% of them indicated that they were never involved. Amongst those that participated, the levels and outcomes also differed greatly. The authors held in-depth interviews with survey participants reporting higher-than-average involvement to find out about their strategies for success
Empowering Ethical Practice: Activities for Access Services
The library profession is guided by a Code of Ethics which explains our values, including privacy, copyright and fair use, equal access, stewardship, and integrity. We continue to serve our publics and garner good will because libraries are perceived as institutions operating in an ethical manner. The Clark Library, University of Portland, desired to empower its staff with a deepened understanding of library ethics. The Access Services Unit, composed of Circulation, Interlibrary Loan, Course Reserves, Reference, Instruction, and a Digital Lab, implemented four activities to intentionally focus on ethics as applied to the day-to-day work of each unit
Business Librarians and New Academic Program Review
The article aims to examine the role business librarians play in the new academic program proposal process on university and college campuses. Results of a nationwide online survey showed that current practices in this critical area varied. While over 60% of the respondents thought that librarians should play a part in the proposal process, over 65% of them indicated that they were never involved. Amongst those that participated, the levels and outcomes also differed greatly. The authors held in-depth interviews with survey participants reporting higher-than-average involvement to find out about their strategies for success
Instant Messaging Transcripts: Pilot Project and Request for Collaborators
Lightning talk on instant messaging transcript
Asymmetric Switching in a Homodimeric ABC Transporter: A Simulation Study
ABC transporters are a large family of membrane proteins involved in a variety of cellular processes, including multidrug and tumor resistance and ion channel regulation. Advances in the structural and functional understanding of ABC transporters have revealed that hydrolysis at the two canonical nucleotide-binding sites (NBSs) is co-operative and non-simultaneous. A conserved core architecture of bacterial and eukaryotic ABC exporters has been established, as exemplified by the crystal structure of the homodimeric multidrug exporter Sav1866. Currently, it is unclear how sequential ATP hydrolysis arises in a symmetric homodimeric transporter, since it implies at least transient asymmetry at the NBSs. We show by molecular dynamics simulation that the initially symmetric structure of Sav1866 readily undergoes asymmetric transitions at its NBSs in a pre-hydrolytic nucleotide configuration. MgATP-binding residues and a network of charged residues at the dimer interface are shown to form a sequence of putative molecular switches that allow ATP hydrolysis only at one NBS. We extend our findings to eukaryotic ABC exporters which often consist of two non-identical half-transporters, frequently with degeneracy substitutions at one of their two NBSs. Interestingly, many residues involved in asymmetric conformational switching in Sav1866 are substituted in degenerate eukaryotic NBS. This finding strengthens recent suggestions that the interplay of a consensus and a degenerate NBS in eukaroytic ABC proteins pre-determines the sequence of hydrolysis at the two NBSs
Effectiveness of nail bed repair in children with or without replacing the fingernail : NINJA multicentre randomized clinical trial
Background
Surgery for nail bed injuries in children is common. One of the key surgical decisions is whether to replace the nail plate following nail bed repair. The aim of this RCT was to assess the clinical effectiveness and cost-effectiveness of nail bed repair with fingernail replacement/substitution compared with repair without fingernail replacement.
Methods
A two-arm 1 : 1 parallel-group open multicentre superiority RCT was performed across 20 secondary-care hospitals in the UK. The co-primary outcomes were surgical-site infection at around 7 days after surgery and cosmetic appearance summary score at a minimum of 4 months.
Results
Some 451 children presenting with a suspected nail bed injury were recruited between July 2018 and July 2019; 224 were allocated to the nail-discarded arm, and 227 to the nail-replaced arm. There was no difference in the number of surgical-site infections at around 7 days between the two interventions or in cosmetic appearance. The mean total healthcare cost over the 4 months after surgery was €84 (95 per cent c.i. 34 to 140) lower for the nail-discarded arm than the nail-replaced arm (P < 0.001).
Conclusion
After nail bed repair, discarding the fingernail was associated with similar rates of infection and cosmesis ratings as replacement of the finger nail, but was cost saving
I See the Ideas : Visual Strategies for Teaching Research Concepts
A discussion of learning styles and how they relate to teaching information research is presented. Suggestions for the design of instructional materials including consideration of contrast, context, and grounding of words are included