18 research outputs found

    The D-SDA Reporting System: Reporting and User Access at DLR-EOC

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    In recent years, Earth observation missions and projects have put ever-increasing emphasis on reporting. Detailed reports are being requested on system performance, user behaviour and processing workload. At the same time reporting is gaining significance for data centres’ internal purposes as well – for identifying bottlenecks and optimizing system performance and reliability. For future planning, Earth Observation data centres increasingly need information-based forecasts. Reliable reports help in planning system evolution and upgrades. The German Satellite Data Archive (D-SDA) at the German Aerospace Centre DLR has established a comprehensive reporting system to respond to a variety of reporting demands – fully integrated with the data and information management system as well as the IT infrastructure. Running in a state-of-the-art software environment, the D-SDA Reporting System is accessible by an easy-to-use interface and offers a high-degree of flexibility regarding input and output formats. This paper will outline the challenges for reporting at DLR-EOC and introduce the reporting system architecture embedded in the D-SDA multi-mission data management environment. It will highlight current developments and future challenge

    Two-step staged resection of giant olfactory groove meningiomas

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    Background!#!The surgical treatment of giant olfactory groove meningiomas (OGMs) with marked perilesional brain oedema is still a surgical challenge. After tumour resection, increase of brain oedema may occur causing dramatic neurological deterioration and even death of the patient. The objective of this paper is to describe surgical features of a two-step staged resection of these tumours performed to counter increase of postoperative brain oedema.!##!Methods!#!This two-step staged resection procedure was carried out in a consecutive series of 19 patients harbouring giant OGMs. As first step, a bifrontal craniectomy was performed followed by a right-sided interhemispherical approach. About 80% of the tumour mass was resected leaving behind a shell-shaped tumour remnant. In the second step, carried out after the patients' recovery from the first surgery and decline of oedema, the remaining part of the tumour was removed completely followed by duro- and cranioplasty.!##!Results!#!Ten patients recovered quickly from first surgery and the second operation was performed after a mean of 12.4 days. In eight patients, the second operation was carried out later between day 25 and 68 due to surgery-related complications, development of a trigeminal zoster, or to a persisting frontal brain oedema. Mean follow-up was 49.3 months and all but one patient had a good outcome regardless of surgery-related complications.!##!Conclusions!#!Our results suggest that a two-step staged resection of giant OGMs minimizes the increase of postoperative brain oedema as far as possible and translates into lower morbidity and mortality

    The ability to return to work: a patient-centered outcome parameter following glioma surgery

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    Background With refinements in diagnosis and therapy of gliomas, the importance of survival time as the sole outcome parameter has decreased, and patient-centered outcome parameters have gained interest. Pursuing a profession is an indispensable component of human happiness. The aim of this study was to analyze the professional outcomes besides their neuro-oncological and functional evaluation after surgery for gliomas in eloquent areas. Methods We assessed neuro-oncological and functional outcomes of patients with gliomas WHO grades II and III undergoing surgery between 2012 and 2018. All patients underwent routine follow-up and adjuvant treatment. Treatment and survival parameters were collected prospectively. Repercussions of the disease on the patients’ professional status, socio-economic situation, and neurocognitive function were evaluated retrospectively with questionnaires. Results We analyzed data of 58 patients with gliomas (WHO II: 9; III: 49). Median patient age was 35.8 years (range 21–63 years). Awake surgery techniques were applied in 32 patients (55.2%). Gross total and subtotal tumor resections were achieved in 33 (56.9%) and 17 (29.3%) patients, respectively, whereas in 8 patients (13.8%) resection had to remain partial. Most patients (n = 46; 79.3%) received adjuvant treatment. Median follow up was 43.8 months (range 11–82 months). After treatment 41 patients (70.7%) were able to resume a working life. Median time until returning to work was 8.0 months (range 0.2–22.0 months). To be younger than 40 at the time of the surgery was associated with a higher probability to return to work (p < .001). Multivariable regression analysis showed that patient age < 40 years as well as occupational group and self-reported fatigue were factors independently associated with the ability to return to work. Conclusion The ability to resume professional activities following brain tumor surgery is an important patient-oriented outcome parameter. We found that the majority of patients with gliomas were able to return to work following surgical and adjuvant treatment. Preservation of neurological function is of utmost relevance for individual patients´ quality of life

    Is postoperative imaging mandatory after meningioma removal? : results of a prospective study

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    Background: Routine postoperative imaging (PI) following surgery for intracranial meningiomas is common practice in most neurosurgical departments. The purpose of this study was to determine the role of routine PI and its impact on clinical decision making after resection of meningioma. Methods: Patient and tumor characteristics, details of radiographic scans, symptoms and alteration of treatment courses were prospectively collected for patients undergoing removal of a supratentorial meningioma of the convexity, falx, tentorium, or lateral sphenoid wing at the authors’ institution between January 1st, 2010 and March 31st, 2012. Patients with infratentorial manifestations or meningiomas of the skull base known to be surgically difficult (e.g. olfactory groove, petroclival, medial sphenoid wing) were not included. Maximum tumor diameter was divided into groups of 6 cm (large). Results: 206 patients with meningiomas were operated between January 2010 and March 2012. Of these, 113 patients met the inclusion criteria and were analyzed in this study. 83 patients (73.5%) did not present new neurological deficits, whereas 30 patients (26.5%) became clinically symptomatic. Symptomatic patients had a change in treatment after PI in 21 cases (70%), while PI was without consequence in 9 patients (30%). PI did not result in a change of treatment in all asymptomatic patients (p<0.001) irrespective of tumor size (p<0.001) or localization (p<0.001). Conclusions: PI is mandatory for clinically symptomatic patients but it is safe to waive it in clinically asymptomatic patients, even if the meningioma was large in size

    Distribution of change of treatment on ICU patients dependent on tumor size.

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    <p>Patients were assigned to the indicated groups dependent on meningioma size. Tumor size of > 6 cm is significantly more often associated with a change in postoperative treatment compared to a tumor size of < 3 cm (p<0.005) and 3–6 cm (p<0.05, Fisher’s exact test)</p

    Distribution of change of treatment on ICU patients dependent on tumor localization.

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    <p>Patients were assigned to the indicated groups dependent on meningioma location. The occurrence of a change in ICU treatment did not differ between tumor location (Fisher’s exact test).</p

    Characteristics of patients suffering deficits at follow-up.

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    <p>Characteristics of patients suffering from permanent neurological deficits. Patients were reevaluated after follow up of 3 months.</p><p>Characteristics of patients suffering deficits at follow-up.</p

    Meningioma location.

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    <p>Exemplary images of meningioma location to demonstrate assessment of location of the tumor as easily accessible in this study.</p
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