Biosynthetic Pattern of Liver Glycogen in Malignancy and Under Therapeutic Stress

The hypoglycemic effect exerted by the tumor tissue causes an increased consumption of blood glucose from the surrounding medium and this in turn results in an elevated mobilization of host\u27s liver glycogen. In the present paper [T-?H] glucose has been injected in normal mice and those bearing S 180, and others treated with the chemotherapeutic agents 5-fluoro uracil and 5-fluoro deoxy uridine causing tumor regression. Information has been furnished in the present paper regarding the utilization pattern of the tritiated glucose in the liver glycogen along with the isotope clearance from the blood in normalcy, malignancy and under therapeutic stress. The check of the neoplastic process due to the therapeutic effectiveness of drugs exhibits parallelism with respect to the significant revival of liver glycogen and the blood glucose level in the treated groups. This is also reflected in the significant increase of incorporation of radioactive precursor in liver glycogen concomitant with decrease in the rate of utilization of isotope from the blood level in the treated series

A study of the prognostic role of serum fucose and fucosyl transferase in cancer of the uterine cervix.

Serum fucose levels and fucosyl transferase activities have been designated as nonspecific markers of malignancy, and play an important role in the diagnosis of different types of malignancies. In the present study, attempts were made to determine the prognostic significance of these markers in patients with cancer of the uterine cervix after therapy. It was found that both serum fucose and fucosyl transferase, which were elevated in untreated patients declined significantly in patients responsive to therapy at different follow-up intervals, but not in patients unresponsive to therapy.</p

Agro-Morphological, Yield and Biochemical Responses of Selected Wheat (<i>Triticum aestivum</i> L.) Genotypes to Salt Stress

Wheat is affected by various biotic and abiotic stresses, especially salinity, which reduces the growth and yield drastically. With this view, an experiment was conducted to observe genotypic differences in agro-morphological, yield, and biochemical responses to salinity. Experimental variables consisted of five salt-tolerant genotypes (G 13, G 20-1, G 9, G 22, G 20-2), one susceptible genotype (G 24) and one standard check variety (BARI ghom 25), which assigned to four levels of salinity with electrical conductivities 0, 4, 8 and 12 dS m−1. Irrespective of genotypes, salinity stress significantly decreased the yield and yield attributes. However, maximum total tillers plant−1, effective tillers plant−1, number of grains spike−1, and grain yield plant−1 was found in salt tolerant genotype G 20-2, followed by genotypes G 13, G 20-1, and the lowest was observed in salt-susceptible genotype G 24. The lowest reduction percentage of yield and yield attributes were also observed in salt tolerant genotype G 20-2 followed by genotypes G 13, G 20-2, and the maximum reduction percentage was found in salt-susceptible genotype G 24. Results showed that the highest amount of proline, glycinebetaine, soluble sugar and soluble protein content were observed in salt-tolerant genotype G 20-2, followed by genotypes G 13, G 20-1, and the minimum was found in salt-susceptible genotype G 24. On the other hand, the lowest hydrogen peroxide (H2O2) and melondealdehyde (MDA) accumulation was detected in the same salt-tolerant genotype G 20-2, followed by G 13, G 20-1, and the maximum was observed in salt-susceptible genotype G 24. Therefore, higher accumulations of compatible solute in the tolerant genotypes reduce the oxidative stress, and provide the higher yield