From presence to participation – the role of the juror reimagined

This article raises new questions about the meaning of juror participation in a criminal trial. Through an interdisciplinary exploration I not only theorize the position and potentiality of the jury, but I also reflect on the process of working with a theatre director to create work which is both academic research and public theatre performance in equal measure. I challenge the reader to reconsider the current assumptions which equate juror presence in the courtroom to their participation in the trial by drawing on participatory techniques found in Augusto Boal's Forum Theatre and my current collaboration with site-specific theatre company, Grid Iron

Is Children\u27s Literature Really Meant for Children? Global Political Commentary in Children\u27s Literature

This thesis explores the way children’s literature is a productive form for political commentary. I analyze how the genre of children’s literature allows authors the unexpected freedom to express the moral complexity of contemporary political problems. This form provides authors a space to comment upon complicated and sometimes controversial political discourse in a way they might not have the freedom to do otherwise writing explicitly for an adult audience. Amidst the argument that children’s literature as a form allows for authors to include political discourse, I also incorporate an examination of the audience of children’s literature to demonstrate the complexity of the form and who it is meant for. People often assume that children’s literature takes up simple topics and simple approaches to more complex topics, but I demonstrate how three classic works approach global political crises with unexpected complexity and nuance. To accomplish these objectives, I discuss these three primary texts among a collection of secondary scholarship to both add to and generate new conversation surrounding the form of children\u27s literature and its potential purposes. The primary texts I analyze are The Jungle Books by Rudyard Kipling, published in 1894 and 1895, The Lion the Witch, and the Wardrobe by C.S. Lewis, published in 1950, and A Wrinkle in Time by Madeleine L’Engle, published in 1962

Can compassion-based interventions (CBIs) improve depressive symptoms in patients with chronic pain? A systematic review and the acute and long-term effects of sub-anaesthetic ketamine on pain, mood and cognitive functioning in chronic pain patients

Part one of this thesis is a systematic review examining the evidence for compassion-based interventions in reducing depressive symptoms in chronic pain patients. Eleven studies were included in the review, of which ten reported improvements in depression symptoms after the completion of a compassion-based intervention. However, there was considerable variation in the quality of the reviewed literature. Part two of this thesis presents an empirical study comparing the acute and long-term effects of sub-anaesthetic ketamine infusions (compared to lidocaine) on pain, mood and cognitive functioning in chronic pain patients. Long-term follow-up data was collected and compared with baseline, mid-infusion, post-infusion and one-week follow-up data. Although ketamine produced superior analgesic effects over lidocaine during the acute phase, this difference between the two groups was no longer present at one-week follow-up or long-term follow-up. Ketamine did not show any specific antidepressant effects in a chronic pain population, either acutely or over the longer-term. Ketamine acutely impaired performance on tasks of episodic memory, verbal fluency and working memory and concentration which was hypothesised to be due to a practice-blocking effect. However, these impairments were no longer observed at long-term follow-up. Part three of this thesis presents a critical appraisal of this research. It reflects on various aspects of the research process, including the impact of COVID-19 and my experiences of conducting research in a clinical setting. This thesis is a joint project with Laura Marks, who completed qualitative analyses of interviews with ketamine patients. Additionally, this is a continuation of a previous project by past UCL DClinPsy trainees: Georgia Halls (2020), Joe Kibble (2020), Matt Knox (2018) and Catherine Trotman (2018)

Spatially Offset Active Galactic Nuclei III: Discovery of Late-Stage Galaxy Mergers with The Hubble Space Telescope

Galaxy pairs with separations of only a few kpc represent important stages in the merger-driven growth of supermassive black holes (SMBHs). However, such mergers are difficult to identify observationally due to the correspondingly small angular scales. In Paper I we presented a method of finding candidate kpc-scale galaxy mergers that is leveraged on the selection of X-ray sources spatially offset from the centers of host galaxies. In this paper we analyze new Hubble Space Telescope (HST) WFC3 imaging for six of these sources to search for signatures of galaxy mergers. The HST imaging reveals that four of the six systems are on-going galaxy mergers with separations of 1.2-6.6 kpc (offset AGN). The nature of the remaining two spatially offset X-ray sources is ambiguous and may be associated with super-Eddington accretion in X-ray binaries. The ability of this sample to probe small galaxy separations and minor mergers makes it uniquely suited for testing the role of galaxy mergers for AGN triggering. We find that galaxy mergers with only one AGN are predominantly minor mergers with mass ratios similar to the overall population of galaxy mergers. By comparison, galaxy mergers with two AGN are biased toward major mergers and larger nuclear gas masses. Finally, we find that the level of SMBH accretion increases toward smaller mass ratios (major mergers). This result suggests the mass ratio effects not only the frequency of AGN triggering but also the rate of SMBH growth in mergers.Comment: 15 pages, 7 figures, accepted for publication in The Astrophysical Journa

Use of the femoral vein ('groin injecting') by a sample of needle exchange clients in Bristol, UK

BACKGROUND: Use of the femoral vein for intravenous access by injecting drug users (IDUs) (commonly called 'groin injecting') is a practice that is often observed but on which little is written in the literature. The purpose of this study was to describe self-reported data from a sample of groin injectors on the natural history and rationale regarding their groin injecting, to inform future research and the development of appropriate harm reduction strategies. METHODS: A convenience sample of groin injectors willing to participate in a semi-structured interview were recruited through the Bristol Drugs Project Harm Reduction Service. The interviews were conducted over the period of one week. Data on transition to groin injecting, rationale for use and incidence of problems were collected. RESULTS: Forty seven IDUs currently injecting in their femoral vein ('groin') were interviewed, 66% (n = 31) male and 34% (n = 16) female. Their mean age was 31 yrs (range 17 to 50 yrs; SD = 7.7). The mean length of time since first injecting episode was 9.6 yrs (range 6 mths to 30 yrs; SD = 7.0). The mean length of time since use of the groin began was 2.6 years (range 1 mth to 15 yrs; SD = 3.3). The mean length of time between first injection and first use of the groin was 7.0 yrs (SD = 7.0). One person had used no other area for venous access prior to using the groin, nine people had used one, nine people had used two, 10 people had used three, five people had used four and 13 people had used more than four areas. The main reason given for starting to inject in the groin was that 'no other sites were left'. However further discussion identified this meant no other convenient sites were accessible. Practises such as the rotation of injecting sites, as advocated in many harm reduction leaflets, were reported to be difficult and unreliable. The risk of missing the vein and subsequently losing the 'hit' was considered high. Use of the non-dominant hand to administer injections was problematic and deterred rotation between arms. The groin site was reported to be convenient, provide quick access, with little mess and less pain than smaller more awkward veins. The formation of sinuses over time facilitated continued use of the groin. Approximately two thirds of participants had experienced difficulty gaining IV access at their groin. Common problem included scar tissue occlusion, swelling and pain. Some reported infections and past history of deep vein thrombosis. CONCLUSION: Use of the groin was perceived to be convenient by the study group. Problems following safer injecting advice were identified, including dexterity difficulties leading to fear of losing the 'hit'. Health problems at the groin site did not deter use. These results suggest further qualitative work is needed to explore the difficulties in following safer injecting advice in more detail and inform the development of more appropriate advice. Further quantitative work is necessary to establish the prevalence of groin injecting amongst IDUs and the incidence of associated problems. There is a need for a longitudinal study to examine the relationship between injecting technique and loss of patency of veins. If protective factors could be identified, evidence-based safer injecting advice could be established to preserve peripheral veins and reduce use of the groin site, which is high risk and associated with serious adverse consequences

The relationship between prenatal testosterone (2D:4D), Big 5 Personality traits and GRIT in different cultural contexts

Digit ratio (2D:4D; a putative correlate of prenatal testosterone) has been shown to be predictive of important personality factors such as mental toughness, optimism and academic achievement. However, to date no study has attempted to investigate prenatal testosterone levels as a predictor of GRIT (persistency and constancy) and the Big 5 personality traits Openness to experience, Conscientiousness, Extraversion, Agreeableness and Neuroticism. Research has also alluded to the potential gender and cultural differences in biological underpinnings of psychological functioning. This study included a sample of Dubai and UK undergraduate students and examined associations between prenatal testosterone (2D:4D), GRIT and Big 5 personality traits (openness to experience, conscientiousness, extraversion, agreeableness and neuroticism). UK and Dubai participants followed the same testing procedure and completed a self-report measure for GRIT and Big 5 personality traits, followed by providing a right-hand scan, which was later used to measure 2D:4D using Vernier Callipers. Results showed that in Dubai participants, the measured psychological variables explained a greater amount of variance in 2D:4D than in UK participants. Openness to experience was a strong significant predictor of 2D:4D in Dubai participants whereas, GRIT, conscientiousness and openness to experience were all significant predictors of 2D:4D for UK participants

Age related factors influence HIV testing within subpopulations: a cross sectional survey of MSM within the Celtic nations

Objectives: Despite a recent fall in the incidence of HIV within the UK, men who have sex with men (MSM) continue to be disproportionately affected. As biomedical prevention technologies including pre-exposure prophylaxis are increasingly taken up to reduce transmission, the role of HIV testing has become central to the management of risk. Against a background of lower testing rates among older MSM, this study aimed to identify age-related factors influencing recent (≤12 months) HIV testing. Methods: Cross-sectional subpopulation data from an online survey of sexually active MSM in the Celtic nations—Scotland, Wales, Northern Ireland and Ireland (n=2436)—were analysed to compare demographic, behavioural and sociocultural factors influencing HIV testing between MSM aged 16–25 (n=447), 26–45 (n=1092) and ≥46 (n=897). Results: Multivariate logistic regression demonstrated that for men aged ≥46, not identifying as gay (OR 0.62, CI 0.41 to 0.95), location (Wales) (OR 0.49, CI 0.32 to 0.76) and scoring higher on the personalised Stigma Scale (OR 0.97, CI 0.94 to 1.00) significantly reduced the odds for HIV testing in the preceding year. Men aged 26–45 who did not identify as gay (OR 0.61, CI 0.41 to 0.92) were also significantly less likely to have recently tested for HIV. For men aged 16–25, not having a degree (OR 0.48, CI 0.29 to 0.79), location (Republic of Ireland) (OR 0.55, CI 0.30 to 1.00) and scoring higher on emotional competence (OR 0.57, CI 0.42 to 0.77) were also significantly associated with not having recently tested for HIV. Conclusion: Key differences in age-related factors influencing HIV testing suggest health improvement interventions should accommodate the wide diversities among MSM populations across the life course. Future research should seek to identify barriers and enablers to HIV testing among the oldest and youngest MSM, with specific focus on education and stigma