579 research outputs found
An illustrated key to Malacostraca (Crustacea) of the Northern Arabian Sea part-V: Isopoda
The northern Arabian Sea Isopod fauna is keyed out, excluding the gulfs fauna. Some terrestrial species are also included. Previous accounts and recent collections
from Pakistan mainly at Karachi have turned up 7 suborders, 18 families, 76 genera and 12 1 species. There 5 are new records from Pakistan. For each species, there is an
illustration and information of its reporter from the area and on its host, if parastic. The source of illustration is also given
Sedimenttransport en sedimentatieprocessen ter hoogte van de polders van Kruibeke, Bazel en Rupelmonde
Summary Report — Antimicrobial Susceptibility: Tests Results from Henry Ford Hospital Compared With Others Nationally, January-June 1969
Fluctuation-induced phase in CsCuCl3 in transverse magnetic field: Theory
CsCuCl3 is a quantum triangular antiferromagnet, ferromagnetically stacked,
with an incommensurate (IC) structure due to a Dzyaloshinskii-Moriya
interaction. Because of the classical degeneracy caused by the frustration,
fluctuations in CsCuCl3 have extraordinarily large effects, such as the phase
transition in longitudinal magnetic field (normal to the planes, parallel to
the IC wavenumber q) and the plateau in q in transverse field (perpendicular to
q). We argue that fluctuations are responsible also for the new IC phase
discovered in transverse field near the Neel temperature T_N, by T. Werner et
al. [Solid State Commun. 102, p.609 (1997)]. We develop and analyse the
corresponding minimal Landau theory; the effects of fluctuations on the
frustration are included phenomenologically, by means of a biquadratic term.
The Landau theory gives two IC phases, one familiar from previous studies;
properties of the new IC phase, which occupies a pocket of the
temperature-field phase diagram near T_N, agree qualitatively with those of the
new phase found experimentally.Comment: 12 pages, revtex, 4 postscript figures, submitted to J. Phys:
Condens. Matte
Flow equation analysis of the anisotropic Kondo model
We use the new method of infinitesimal unitary transformations to calculate
zero temperature correlation functions in the strong-coupling phase of the
anisotropic Kondo model. We find the dynamics on all energy scales including
the crossover behaviour from weak to strong coupling. The integrable structure
of the Hamiltonian is not used in our approach. Our method should also be
useful in other strong-coupling models since few other analytical methods allow
the evaluation of their correlation functions on all energy scales.Comment: 4 pages RevTeX, 2 eps figures include
A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 Acute Lymphocytic Leukemia cells
MLL-AF4 Acute Lymphocytic Leukemia has a poor prognosis, and the mechanisms by which these leukemias develop are not understood despite intensive research based on well-known concepts and methods. MicroRNAs (miRNAs) are a new class of small noncoding RNAs that post-transcriptionally regulate expression of target mRNA transcripts. We recently reported that ectopic expression of miR-128b together with miR-221, two of the miRNAs downregulated in MLL-AF4 ALL, restores glucocorticoid resistance through downregulation of the MLL-AF4 chimeric fusion proteins MLL-AF4 and AF4-MLL that are generated by chromosomal translocation t(4;11). Here we report the identification of new mutations in miR-128b in RS4;11 cells, derived from MLL-AF4 ALL patient. One novel mutation significantly reduces the processing of miR-128b. Finally, this base change occurs in a primary MLL-AF4 ALL sample as an acquired mutation. These results demonstrate that the novel mutation in miR-128b in MLL-AF4 ALL alters the processing of miR-128b and that the resultant downregulation of mature miR-128b contributes to glucocorticoid resistance through the failure to downregulate the fusion oncogenes.National Institutes of Health (U.S.) (NIH Grant R01 DK068348)Netherlands Organization for Scientific ResearchDutch Cancer SocietyJapan Society for the Promotion of Scienc
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