Ensemble Equivalence for Counterion Condensation on a Two Dimensional Charged Disc

We study the counterion condensation on a two dimensional charged disc in the limit of infinite dilution, and compare the energy-temperature relation obtained from the canonical free energy and microcanonical entropy. The microcanonical entropy is piecewise linear in energy, and is shown to be concave for all energies. As a result, even though the interactions are long-ranged, the energy-temperature relation and hence the counterion condensation transition points are identical in both the ensembles.Comment: 4 pages, 2 figure

2011. Green synthesis of silver nanoparticles by using derived callus extract of bitter apple (Citrullus colocynthis

Citrullus colocynthis belong to the family of cucurbitaceae are purgative and used for the treating mamilities, jaundice and urinary disease Plant mediated synthesis of metallic nanoparticles is an increasing commercial demand due to the wide applicability in various areas such as electronics, catalysis, chemistry, energy, cosmetics and medicine. In the present investigation, synthesis of silver nanoparticles by using stem derived callus extracts of Citrullus colocynthis (L.) Schrader. The extract incubated with AgNO 3 showed gradual change in the colour of the extract from greenish to reddish brown it indicate the silver nanopaticles synthesis. The shape of the SNP synthesized by stem derived callus extract was spherical and was found to be in the range of 75 nm by AFM. FTIR absorption spectra conclude that the compounds attached with silver nanoparticles could be polyphenols with aromatic ring and bound amide region. The novel silver nanoparticles exhibited a tremendous antibacterial activity; it showed the maximum activity against bioflim bacteria such as E.coli (10.1 mm), V. paraheamolyticus (10.1 mm), P. aeruginosa (8 mm), Proteus vulgaris (9 mm) and L. monocytogens (8 mm) and also observed that it showed no activity against Proteus mirabilis, Salmonella enteritidis, and Staphylococcus aureus. To the best of our knowledge this is the first report on the antibacterial activity of silver nanoparticles against bioflim forming bacteria

Antidiabetic effect of a black mangrove species Aegiceras corniculatum in alloxan-induced diabetic rats

Earlier ethnopharmacological records divulged the traditional usages of mangrove Aegiceras corniculatum (Linn.) Blanco distributed in coastal and estuarine areas of Southeast India. Excluding scientific knowledge of A. corniculatum against diabetes an upgrowing endocrinal disorder, our present study evaluated the effect on alloxan-induced diabetic rats. Diabetes was induced in adult rats of the Wistar strain by intraperitoneal injection of alloxan monohydrate. The experimental rats were administered with leaf suspension of A. corniculatum post orally using an intragastric tube. On completion of the 60-day treatment, a range of biochemical parameters were tested including liver hexokinase, glucose-6phosphatase and fructose 1, 6 bisphosphatase in the liver of control and allaxon-diabetic rats. As a result, A. corniculatum leaf suspension showed moderate reduction in blood glucose (from 382 ± 34 to 105 ± 35), glycosylated hemoglobin, a decrease in the activities of glucose-6 phosphatase and fructose 1, 6-bisphosphatase, and an increase activity of liver hexokinase achieved through the oral administration of extract on 100 mg/kg. The present findings support promising results in terms of antidiabetic activities establishing its candidacy for further purification of individual compound in order to understand their mechanism of action

Total synthesis of (−)-Sachalinol A and evaluation of its cytotoxicity

695-700(-)-Sachalinol A, a group of monoterpenoids, oxygenated derivatives of rosinidol, has been synthesized employing a simple, eight step procedure. The compound demonstrates excellent cytotoxicity against MDA-MB-231 derived from human breast adenocarcinoma cells (ATCC No. HTB-26) and HeLa derived from human cervical cancer cells (ATCC No. CCL-2). Good activity is observed against A549 derived from human alveolar adenocarcinoma epithelial cells (ATCC No. CCL-185) and Neuro2a derived from mouse neuroblastoma cells (ATCC No. CCL-131). Moderate activity is also observed against MCF-7 derived from human breast adenocarcinoma cells (ATCC No. HTB-22)