Numerical Analysis of the Disequilibrium Monetary Growth Model: Secular Stagnation, Slow Convergence, and Cyclical Fluctuations

This study presents a monetary disequilibrium growth model and conducts numerical simulations to investigate how dynamic paths are affected by the initial conditions and the parameters of expectation formation. The main results are as follows. First, dynamic properties such as stable convergence and cyclical fluctuations depend on the type of expectation formation rather than on the initial regimes. Stable convergence takes an excessively long time when expectation formation is too rational and cyclical fluctuations appear when it is too adaptive. Second, when the economy converges to the steady state (i.e., the Walrasian equilibrium), persistent Keynesian unemployment is likely to appear along the dynamic path. Third, the dynamics of inflation expectation that contain the price dynamics in the feedback loop might play an important role in convergence to the steady state

SEX-BASED DIFFERENCES IN TRUNK ACCELERATION AND LANDING POSTURE DURING THE DROP VERTICAL JUMP TEST

The purpose of this study was to investigate sex-based differences in trunk acceleration and landing posture during the drop vertical jump test and to determine the relationships among relevant variables. Twenty college students (10 men and 10 women) performed drop vertical jumps from a 30cm high box. Trunk acceleration and the trunk, limb, knee, and ankle angles in the sagittal plane were measured. The unpaired Student t-test and Pearson product-moment correlation coefficients were used for statistical analysis. Female participants demonstrated greater vertical trunk acceleration and smaller trunk angles than male participants did. In addition, vertical acceleration correlated with trunk and limb angles. Therefore, these parameters, which can be estimated by using wearable sensors, may be useful for checking athletes at high risk for injury

GENDER DIFFERENCES OF TRUNK AND LOWER LIMB POSITIONS DURING THE CUTTING MANEUVER

The purpose of this study was to analyze the gender differences in positions of the trunk and lower limb during the cutting maneuver. We captured the trunk and lower limb positions during shuttle-run cutting in 8 male and 7 female soccer players. The distance from the center of the trunk to the foot-plant point in the frontal and sagittal planes, knee flexion angle, knee valgus angle, femoral inclination angle, trunk forward-inclination angle, and trunk lateral-inclination angle were measured. Our results showed that female subjects demonstrated less femoral inclination, greater trunk lateral inclination away from the cutting limb, and smaller distance from the center of the trunk to the foot-plant point in the frontal plane than male subjects. The study results may reveal potential risks for ACL injury

Diversity of glial cell components in pilocytic astrocytoma

To characterize the cellular density and proliferative activity of glial fibrillary acidic protein (GFAP)-negative cells in pilocytic astrocytoma (PA), surgically excised tissues of PAs (n=37) and diffuse astrocytomas (DAs) (n=11) were examined morphologically and immunohistochemically using antibodies against GFAP, Olig2, Iba1 and Ki-67 (MIB-1). In PA, Olig2 immunoreactivity was significantly expressed in protoplasmic astrocytes in microcystic, loose areas and cells in oligodendroglioma-like areas. Iba1-positive, activated microglia/macrophages were also commonly observed in microcystic areas. In compact areas, a prominent reaction for GFAP was observed, but for Olig2 and Iba1 to a lesser degree. On semiquantitative analysis, the number of Olig2-positive cells was significantly higher in PAs (mean labeling index (LI) ± standard deviation (SD): 46.8 ± 15.4%) than in DAs (13.3 ± 7.8%) (P<0.001). Many Iba1-positive, microglia/macrophages were observed in PAs (19.9 ± 6.5%), similarly to DAs (20.9 ± 9.9%). Re-immunostaining of PA demonstrated that most Ki-67-positive, proliferating cells expressed Olig2, whereas GFAP or Iba1 expression in Ki-67-positive cells was less frequent (14.7 ± 13.7%, and 8.8 ± 13.6%) in a double immunostaining study. Conversely, the percentage of Olig2-positive, proliferating cells in total Olig2-positive cells (7.2 ± 3.9%) was higher than that of Iba1-positive, proliferating cells in total Iba1-positive cells (0.9 ± 0.6%). In conclusion, the present study found that PA consisted of numerous GFAP-negative cells, including Olig2-positive cells with high proliferation. Semiquantitative analysis of Olig2 immunohistochemistry in microcystic areas might therefore be useful for the differential diagnosis of PA and DA学位記番号：医博甲1088, 学位の種類：博士（医）, 学位授与年月日：平成20年3月25

Hibonite-bearing inclusions from Murchison (CM2) meteorite: A Mg isotopic study using a NanoSIMS.

第2回極域科学シンポジウム/第34回南極隕石シンポジウム 11月17日（木） 国立国語研究所 2階講

Near-Infrared Extinction in The Coalsack Globule 2

We have conducted J, H, and Ks imaging observations for the Coalsack Globule 2 with the SIRIUS infrared camera on the IRSF 1.4 m telescope at SAAO, and determined the color excess ratio, E(J-H)/E(H-Ks). The ratio is determined in the same photometric system as our previous study for the rho Oph and Cha clouds without any color transformation; this enables us to directly compare the near-infrared extinction laws among these regions. The current ratio E(J-H)/E(H-Ks) = 1.91 +- 0.01 for the extinction range 0.5 < E(J-H) <1.8 is significantly larger than the ratios for the rho Oph and Cha clouds (E(J-H)/E(H-Ks) = 1.60-1.69). This ratio corresponds to a large negative index alpha = 2.34 +- 0.01 when the wavelength dependence of extinction is approximated by a power law which might indicate little growth of dust grains, or larger abundance of dielectric non-absorbing components such as silicates, or both in this cloud. We also confirm that the color excess ratio for the Coalsack Globule 2 has a trend of increasing with decreasing optical depth, which is the same trend as the rho Oph and Cha clouds have.Comment: 13 pages, 5 figures, and 2 tables, Ap

Proliferation and cell death of human glioblastoma cells after carbon-ion beam exposure: Morphologic and morphometric analyses

Histological analyses of glioblastoma cells after carbon-ion exposure are still limited and ultrastructural characteristics have not been investigated in detail. Here we report the results of morphological and morphometric analyses of a human glioblastoma cell line, CGNH-89, after ionizing radiation to characterize the effect of a carbon-beam on glioblastoma cells. Using CGNH-89 cells exposed to 0–10 Gy of X-ray (140kVp) or carbon-ions (18.3 MeV/nucleon, LET = 108 keV/μm), we performed conventional histology and immunocytochemistry with MIB-1 antibody, transmission electron microscopy, and computer-assisted, nuclear size measurements. CGNH-89 cells with a G to A transition in codon 280 in exon 8 of the TP53 gene had nuclei with pleomorphism, marked nuclear atypia and brisk mitotic activity. After carbon-ion and X-ray exposure, living cells showed decreased cell number, nuclear condensation, increased atypical mitotic figures, and a tendency of cytoplasmic enlargement at the level of light microscopy. The deviation of the nuclear area size increased during 48 hours after irradiation, while the small cell fraction increased in 336 hours. In glioblastoma cells of the control, 5 Gy carbon-beam, and 10 Gy carbon-beam, and MIB-1 labeling index decreased in 24 hours (12%, 11%, 7%, respectively) but increased in 48 hours (10%, 20%, 21%, respectively). Ultrastructurally, cellular enlargement seemed to depend on vacuolation, swelling of mitochondria, and increase of cellular organelles, such as the cytoskeleton and secondary lysosome. We could not observe apoptotic bodies in the CGNH-89 cells under any conditions. We conclude that carbon-ion irradiation induced cell death and senescence in a glioblastoma cell line with mutant TP53. Our results indicated that the increase of large cells with enlarged and bizarre nuclei, swollen mitochondria, and secondary lysosome occurred in glioblastoma cells after carbon-beam exposure.学位記番号：医博甲1096, 学位の種類：博士（医）, 学位授与年月日：平成20年3月25

Craniomaxillofacial Fibrous Dysplasia Improved Cosmetic and Occlusal Problem by Comprehensive Treatment: A Case Report and Review of Current Treatments

Fibrous dysplasia (FD) is a fibrous lesion of immature bone, with an incidence of 10-20% in the head and neck region. Most cases are monostotic, but when a lesion occurs on the maxillofacial region and spreads to the surrounding bone, it is classified as polyostotic, despite its localized occurrence. In some cases, surgical intervention is required to improve the cosmetic or functional disturbance of a FD in the maxillofacial region, but it is necessary to confirm symmetry of the maxillofacial region in real time, and a surgical support system is required to compensate. Furthermore, prosthetic intervention is considered when postoperative acquired defects occur or further cosmetic or occlusal function improvement is needed. A comprehensive approach by an oral surgeon and a maxillofacial prosthodontist is necessary for the successful treatment and rehabilitation of such patients. In this article, we describe the case of a craniomaxillofacial FD patient with facial asymmetry and denture incompatibility with improved quality of life measures by integrating surgical treatment using a navigation system and postoperative prosthetic rehabilitation. We also discuss recent diagnostic methods and treatment strategies for craniomaxillofacial FD in the literature

How Does Automation Affect Economic Growth and Income Distribution in a Two-Class Economy?

This study uses a growth model with automation technology to consider two classes---workers and capitalists---and investigates how advances in automation technology affect economic growth and income distribution. In addition to the two production factors labor and traditional capital, we consider automation capital as the third production factor. We also introduce Pasinetti-type saving functions into the model to investigate how the difference between the capitalists' and workers' saving rates affect economic growth and income distribution. When the capitalists' saving rate is higher than a threshold level, per capita output exhibits endogenous growth irrespective of the workers' savings rate. In this case, the income gap between workers and capitalists widens over time. When the capitalists' saving rate is less than the threshold level, two different long-run states occur depending on the workers' saving rate: the capitalists' own automation capital share approaches a constant, and it approaches zero. In both cases, the per capita output growth is zero and the income gap between the two classes becomes constant over time

Transcriptomic comparison between beetle strains selected for short and long durations of death feigning

The molecular basis of death feigning, an antipredator behavior that has received much attention recently, was analyzed. We compared the gene expression profiles of strains with different behaviors, i.e., different durations of death feigning, in the beetle Tribolium castaneum. Beetles artificially selected for short (S) and long (L) durations of death feigning for many generations were compared thoroughly by RNA sequencing. We identified 518 differentially expressed genes (DEGs) between the strains. The strains also showed divergence in unexpected gene expression regions. As expected from previous physiological studies, genes associated with the metabolic pathways of tyrosine, a precursor of dopamine, were differentially expressed between the S and L strains; these enzyme-encoding genes were expressed at higher levels in the L strain than in the S strain. We also found that several genes associated with insulin signaling were expressed at higher levels in the S strain than in the L strain. Quantitative real-time PCR analysis showed that the relative expression levels of Tchpd (encoding 4-hydroxyphenylpyruvate dioxygenase, Hpd) and Tcnat (encoding N-acetyltransferase, Nat) were significantly higher in the L strain than in the S strain, suggesting the influence of these enzymes on the supply of dopamine and duration of death feigning