Contemporary Trends in the Regenerative and Sustainable Built Environment:Technical and Managerial Aspects: workshop proceedings: Novel Energy for the Regenerative Built Environment: Technical and Managerial Aspects, 3-6 March 2014, Istanbul Technical University; [and] Low Carbon Buildings and Communities in the Sustainable Built Environment, 23-25 February 2015, Istanbul Technical University

As the world’s living conditions are deteriorating, the need for the regenerative and sustainable built environment is increasing. Establishment of the regenerative and sustainable built environment requires interdisciplinary work and research. For this reason, our workshop “Low carbon Buildings and Communities in the Sustainable Built Environment” supported by the British Council Researcher Links as well as our workshop “Novel Energy for the Regenerative Built Environment: Technical and Managerial Aspects” supported by the Turkish Science Foundation (TÜBİTAK) play an important role in bringing the academics from various disciplines together. This workshop proceedings book provides the proceedings of these two workshops

Community engagement as a tool to help deliver smart city innovation: a case study of Nottingham, United Kingdom

Cities are complex urban conurbations and facing many challenges. The majority of the world’s population now live in cities and consume 80% of the resources. 'Smart City' innovation is emerging as a major response to the challenges cities are facing. Much of the focus remains on technological interventions, but technology alone may not be sufficient to reach smart and sustainable city goals. Cities are made up of people who have influence and are therefore key stakeholders in the development of smart city innovation and cannot be ignored. This paper aims to explore community engagement in Nottingham to help deliver smart city innovation and the way Nottingham City Council is engaging local communities in its smart projects. The paper analyses the community engagement strategy of Nottingham developed as part of the EU funded smart city project, REMOURBAN (REgeneration MOdel for accelerating the smart URBAN transformation). The main drivers and barriers to effective community engagement are identified in the smart city context. This exploratory study adopted a case study strategy and qualitative research methods. The data was collected through thirteen semi-structured interviews with middle and senior managers in Nottingham City Council and other stakeholder organisations in the city and a focus group of five community leaders from three local community groups. The content analysis of the REMOURBAN documents related to citizen engagement and the council’s energy strategies and policies was carried out. The key results are discussed with recommendations to nurture effective community engagement as a smart city tool and conclusions are drawn

PP-005 Clarithromycin resistance assessment in Helicobacter pylori isolates by using 23S rRNA gene molecular markers

Background: H. pylori is a relatively fastidious and microaerophilic microorganism and therefore standard phenotypic susceptibility tests, even in the hands of experts, are slow and can take at least 10 14 days. Molecular based diagnostic assays by using molecular markers for resistance detection offer an attractive alternative approach to obtain susceptibilities to antibiotics with greater accuracy and speed, and the possibility of a same day result. The aim of this study is the assessment of clarithromycin resistance by using molecular markers. Methods: This cross-sectional descriptive study was performed on 200 gastric biopsy specimens which were obtained from patients undergoing upper gastrointestinal tract endoscopy in Hajar hospital of Shahrekord, by using TaqMan real-time PCR. Initially, H. pylori strains were identified by RUT and PCR. Then, by this regard that accumulation of mutations associated with resistance to clarithromycin were in the region between nucleotides 2142 2144 of 23S rRNA gene, the first probe was designed to be able the distinguish between sensitive and resistant strains. Finally four probes were designed that each be able to identify only one mutation associated with a particular level of clarithromycin resistance. Results: Out of 200 samples, 164 (82%) were H. pylori positive. Overall, clarithromycin susceptible strains were detected in 105 (64.02%) patients and clarithromycin resistance were detected in 59 (35.98%) which were identified as 4 (2.44%) A2144G, 26 (15.85%) A2143G, 15 (9.15%) A2143C and 20 (12.19%) A2142G point mutations. Purely resistant strains were detected in 38 (23.17%), while heteroresistant were found in the remaining 16 (9.76%) cases. Genotype of 5 (8.47%) strains was not detected. This data was confirmed by PCR-RFLP technique. Conclusion: Results showed that Real-time PCR assay in combination with molecular markers has high accuracy to simultaneously identify H. pylori and clarithromycin resistance types directly in gastric biopsy specimens in short time