Aneurysmal coronary arteriovenous fistula closing with covered stent deployment: A case report and review of literature

Coronary arteriovenous fistula (CAVF) is a rarely encountered congenital coronary anomaly, in which coronary artery blood flow bypasses the myocardial capillary network and usually drains to a heart chamber or great vessel. It is usually asymptomatic. However, the risk of symptoms and complications increases with age. High output heart failure, pulmonary hypertension, myocardial ischemia and infective endocarditis may complicate the course of this anomaly. The appearance, and even rupture, of a saccular aneurysm is one of the even rarer complications of CAVF. Here we describe a 57 year-old patient with incidental finding of an aneurysmal CAVF which was treated successfully using covered stent. (Cardiol J 2011; 18, 5: 556–559

CXC Ligand 5 cytokine serum level in women with polycystic ovary syndrome and normal body mass index: A case-control study

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disease and associated with insulin resistance. CXC Ligand 5 (CXCL5) is a new cytokine which is secreted from white adipose tissue during obesity and by blocking insulin signaling pathway inhibits the activity of insulin and promotes insulin resistance. Objective: The aim of this study was to assess serum level of CXCL5 in PCOS women with normal body mass index. Materials and Methods: In this case-control study, 30 PCOS women with normal body mass index as the case group and 30 non-PCOS women as the controls were enrolled. Serum levels of CXCL5, insulin and other hormones factors related with PCOS were measured by ELISA method, also the biochemical parameters were measured by autoanalyzer. Results: Significant increases in serum insulin concentration, homeostasis model assessments of insulin resistance, luteinizing hormone, luteinizing hormone/folliclestimulating hormone, fasting blood sugar, testosterone, and prolactin were observed in the case group compared to the controls. were in the serum level of CXCL5, cholesterol, low-density lipoprotein-cholesterol, high-density lipoproteincholesterol, dehydroepiandrosterone-sulfate, creatinine, and homeostasis model assessment of beta cell function between these two groups. Conclusion: In this study, no significant change was observed in serum concentrations of CXCL5 in PCOS women with normal BMI

Experimental dataforsynthesisofbi-metalized chitosanparticleforattenuatingofanazodye fromwastewater

In thisdataarticle,weintroducedataacquiredfromnewadsor- bent, bi-metalizedchitosanparticlethatissuccessfullysynthesized and appliedtoremovetheorangeIIdye,anazodye,fromtextile wastewater.Theadsorbentwasmeso-andmacro-porousmaterial with BETsurfaceareaof12.69m2/g andpHzpc 6.6. Thesimulated textile-wastewatercanbesignificantly treatedusingarelatively low quantityoftheadsorbent.Overall,theuseofbi-metalized chitosan particlecanbeconsideredapromisingmethodforelim- inating theazodyefromwastewatereffectively.Accordingly,these data willbeusefulfordecolorizingofazodyesfromtextilewas- tewater

Data ontherelationshipbetweenbromide contentandtheformationpotential of THMs,HAAs,andHANsuponchlorination and monochloraminationofKaroon Riverwater,Iran

This dataarticlereportstherelationshipbetweenofthebromide ion concentrationandtheformationpotentialofdisinfectant byproducts(DBPs)including,trihalomethanes(THMs),haloacetic acids (HAAs),andhaloacetonitriles(HANs)uponchlorinationand monochloramination oftherawwaterofKaroonRiverwaterin Iran.Watersampleswerecollectedatanintakeofadrinkingwater treatment plantduringJuly2014.Alltestswereperformedintri- plicate (n¼3) andthemeanofthreemeasurementsreported herein. ThedataoftheformationpotentialofDBPswasdeter- mined underdifferentbromideionscontent.Thedatashowthe relationship betweenbromideconcentrationandDBPsformation that willbeusefulinthefuturemanagement,operationanddesign of watertreatmentplants. & 2016TheAuthors.PublishedbyElsevierInc.Thisisanopen access articleundertheCCBYlicens

Comparison of the Prevalence of Psychiatric Disorders in Performance-Enhancing Drug Users and Nonuser Bodybuilders

Objective: The present study aimed at comparing the prevalence of major psychiatric disorders including major depressive disorder, bipolar disorder, schizophrenia, and generalized anxiety disorder between performance-enhancing drug users and nonuser bodybuilders. Moreover, the prevalence of major psychiatric disorders in bodybuilders was also reported. Method: In this study, 453 athletes were recruited from Bushehr bodybuilding gyms from February to May 2015. A structured questionnaire was used to collect the participants’ information, including demographic characteristics, sports’ status and performance-enhancing drug use. According to the condition of performance-enhancing drug use, the participants were divided into current users, non-current users, and nonusers. The psychiatric status of the participants was evaluated using DSM-IV diagnostic criteria for major depressive disorder, bipolar disorder, generalized anxiety disorder, and schizophrenia. We also asked about the acute psychotic disturbances after using performance-enhancing drugs, alcohol use, and history of aggressive behavior in bodybuilders. Data were analyzed using one-way analysis of variance and chi-square tests. Results: Prevalence of major depressive disorder, bipolar disorder, schizophrenia, generalized anxiety disorder, and the overall prevalence of psychiatric disorders in the bodybuilders was 19.7%, 3.8%, 1.5%, 16.6%, and 26.7%, respectively. After using performance-enhancing drugs, 33% of the bodybuilders had experienced acute psychological disturbances. There were no significant differences between current, non-current, and nonuser bodybuilding athletes in the measured psychiatric disorders. Conclusion: Prevalence of psychiatric disorders was not significantly different in performance-enhancing drug users and nonusers. Thus, it can be concluded that performance-enhancing drugs do not increase the risk of psychiatric disorders in bodybuilders

Zamknięcie tętniakowato poszerzonej przetoki tętniczo-żylnej naczyń wieńcowych z użyciem stentu powlekanego: opis przypadku i przegląd piśmiennictwa

Przetoka tętniczo-żylna naczyń wieńcowych (CAVF) jest rzadko spotykaną wrodzoną wadą naczyń wieńcowych, w której krew omija układ włośniczek miokardium i wpływa bezpośrednio do komór serca lub dużych naczyń. Najczęściej nie powoduje żadnych objawów, ale ryzyko ich pojawienia się oraz wystąpienia powikłań wzrasta wraz z wiekiem. Do głównych powikłań zalicza się niewydolność serca, nadciśnienie płucne, chorobę niedokrwienną serca oraz infekcyjne zapalenie wsierdzia. Powstanie, a nawet pęknięcie, tętniaka workowatego stanowi jedno z najrzadszych powikłań CAVF. W niniejszej pracy opisano 57-letniego pacjenta z przypadkowo wykrytym tętniakiem CAVF skutecznie leczonym wszczepieniem stentu powlekanego (Folia Cardiologica Excerpta 2012; 7, 2: 115-119

Effect of noise pollution on testicular tissue and hormonal assessment in rat

Many studies have focused on the effect of noise stress on the health. So far, few studies have been conducted on the effect of noise on reproductive system. The aim of study was to investigate the effect of noise pollution on morphometric parameters of testicular tissue and hormonal assessment (ACTH, cortisol and testosterone). In this study, 40 male rats were exposed to control, 95, 105 and 115 dB noise intensity for sixty days. At the end of study, blood sampling was performed and ACTH, cortisol and testosterone concentrations were assessed. The results showed that noise stress decreased testosterone levels in the 115 dB-treated group, while it increased the ACTH and cortisol levels. Histological sections of testis showed that the mean diameter of the seminiferous tubules and thickness of the germinal epithelium reduced compared to the control group. Also the ratio of the interstitial tissue area to the total testicular tissue area was increased significantly. Our study shows that noise stress may have negative influences on male fertility

HYPEROXIC PRECONDITIONING FAILS TO CONFER ADDITIONAL PROTECTION AGAINST ISCHEMIA-REPERFUSION INJURY IN ACUTE DIABETIC RAT HEART

Experimental studies show that detrimental effects of ischemia-reperfusion (I/R) injury can be attenuated by hyperoxic preconditioning in normal hearts, however, there are few studies about hyperoxia effects in diseased myocardium. The present study was designed to assess the cardioprotective effects of hyperoxia pretreatment (≥ 95 % O2) in acute diabetic rat hearts. Normal and one week acute diabetic rats were either exposed to 60 (H60) and 180 (H180) min of hyperoxia or exposed to normal atmospheric air (21 % O2). Then hearts were isolated immediately and subjected to 30 min of regional ischemia followed by 120 min of reperfusion. Infarct size, cardiomyocyte apoptosis, enzymes release and ischemia induced arrhythmias were determined. Heart of diabetic control rats had less infarct size and decreased LDH and CK-MB release compared to normal hearts. 60 and 180 min of hyperoxia reduced myocardial infarct size and enzymes release in normal hearts. 180 min of hyperoxia also decreased cardiomyocytes apoptosis in normal state. On the other hand, protective values of hyperoxia were not significantly different in diabetic hearts. Moreover, hyperoxia reduced severity of ventricular arrhythmias in normal rat hearts whereas; it did not confer any additional antiarrhythmic protection in diabetic hearts. These findings suggest that diabetic hearts are less susceptible to ischemia-induced arrhythmias and infarction. Hyperoxia greatly protects rat hearts against I/R injury in normal hearts, however, it could not provide added cardioprotective effects in acute phase of diabetes

Anti-inflammatory and Wound Healing Activities of Aloe vera, Honey and Milk Ointment on Second-Degree Burns in Rats

The aim of the present study was morphological and morphometric investigation of burn healing impacts of an honey, milk, and Aloe vera (HMA) ointment on experimentally induced second-degree burns, to approve the medicinal basis of its use in Iranian traditional medicine. A total of 21 male Albino rats weighing 200 to 300 g were divided into 3 groups of 7, including (1) control group, (2) positive control group, and (3) the treatment group that were treated with eucerin, silver sulfadiazine 3% and HMA ointment 5% respectively. After anesthetizing, the second-degree burns (1 cm2 areas) were made on the back of the animals using a digital controlled hot plaque, and each group was treated topically, based on the time scheduled. Then, skin punch biopsies were obtained on the 1st, 14th, and 28th days of post–burn induction; processed; and stained using hematoxylin and eosin and Masson’s trichrome methods. The results showed that HMA ointment induces cell proliferation, increasing the wound closure rate, blood vessel counts, and collagen fiber density in treated animals. It also reduced the wound secretions, inflammation, and scar formation. According to the obtained morphological, morphometric results, we concluded that the traditional HMA ointment, which is rich in therapeutic biomaterials and minerals, has multiple healing effects on burn wounds in rats. Keywords burn, wound healing, biomaterial, morphometri

Serum visfatin and vaspin levels in normoglycemic first-degree relatives of Iranian patients with type 2 diabetes mellitus

Aim: To investigate circulating visfatin and vaspin levels in first-degree relatives of subjects with type 2 diabetes mellitus (FDRs) who frequently have higher value of HOMA-IR and beta cell dysfunction. Methods: Serum visfatin and vaspin concentrations were measured in 179 Iranian subjects (90 normoglycemic FDRs and 89 age- and sex-matched healthy controls) using enzymelinked immunosorbent assay (ELISA) methods. Result: Serum visfatin levels were significantly lower in the FDRs when compared to the controls (1.71 � 0.93 ng/ml versus 2.69 � 2.02 ng/ml, p = 0.0001). However, no significant difference was found in serum vaspin concentrations between the FDRs and the controls (0.452 � 0.254 ng/ml versus 0.409 � 0.275 ng/ml, p > 0.05). In multiple logistic regression analysis, the FDRs showed a significant association with lower visfatin levels after adjustments for age, sex, Body Mass Index, systolic and diastolic blood pressures, lipid profile, blood glucose levels and HOMA-IR [odds ratios (OR) = 1.71, 95% confidence interval (1.30–2.25); p < 0.0001]. Conclusion: The FDRs showed a significant association with lower visfatin levels. The observed lower circulating visfatin levels in FDRs may suggest a pathophysiological role for visfatin in beta cell dysfunction in this group